CAS 1276013-77-4

Fórmula: C19H23FN2O2

InChI: InChI=1S/C19H23FN2O2/c1-13(19(2,3)4)22-18(23)15-8-9-17(21-11-15)24-12-14-6-5-7-16(20)10-14/h5-11,13H,12H2,1-4H3,(H,22,23)/t13-/m1/s1

Chave InChI: VOYBJCDMLJODRK-CYBMUJFWSA-N

SMILES: C[C@H](C(C)(C)C)NC(=O)C1=CN=C(C=C1)OCC2=CC(=CC=C2)F

(R)-6-(3-Fluoro-benzyloxy)-N-(1,2,2-trimethyl-propyl)-nicotinamide

Produto Controlado

CAS: 1276013-77-4

Applications This compound acts as a potent non-MPEP site mGlu5 positive allosteric modulator with potential application in neuropathic treatment and anti-depressants.
References Manka, J.T. et al.: Bioorg. Med. Chem., 22, 6481 (2012);

Fórmula: C₁₉H₂₃FN₂O₂

Cor e Forma: Neat

Peso molecular: 330.4

Ref: TR-F588395

(R)-6-(3-Fluoro-benzyloxy)-N-(1,2,2-trimethyl-propyl)-nicotinamide-d4

Produto Controlado

CAS: 1276013-77-4

Fórmula: C₁₉H₁₉D₄FN₂O₂

Cor e Forma: Neat

Peso molecular: 334.42

Ref: TR-F588397

VU0404251

CAS: 1276013-77-4

VU0404251 is a positive allosteric modulator of mGlu5.

Fórmula: C₁₉H₂₃FN₂O₂

Cor e Forma: Solid

Peso molecular: 330.4

Ref: TM-T29130