CAS 128-57-4

Sennosídeo B

Descrição:

Sennosídeo B, com o número CAS 128-57-4, é um composto natural derivado principalmente das folhas e vagens da planta Senna, particularmente Senna alexandrina. Pertence a uma classe de compostos conhecidos como antraquinonas, que são caracterizados por sua estrutura aromática policíclica. Sennosídeo B é reconhecido por suas propriedades laxantes, funcionando como um laxante estimulante ao promover a peristaltismo nos intestinos. É frequentemente utilizado na medicina herbal e em formulações de laxantes de venda livre. O composto é tipicamente encontrado na forma de um pó amarelado e é solúvel em água, o que facilita sua absorção e eficácia no trato gastrointestinal. Além de seus efeitos laxantes, Sennosídeo B tem sido estudado por suas potenciais propriedades antioxidantes e anti-inflamatórias. No entanto, seu uso deve ser abordado com cautela, pois o consumo excessivo pode levar a efeitos adversos, como cólicas abdominais e diarreia. No geral, Sennosídeo B é um composto significativo tanto nas práticas medicinais tradicionais quanto modernas, particularmente no tratamento da constipação.

Fórmula: C₄₂H₃₈O₂₀

InChI: InChI=1/C42H38O20/c43-11-23-31(47)35(51)37(53)41(61-23)59-21-5-1-3-15-25(17-7-13(39(55)56)9-19(45)27(17)33(49)29(15)21)26-16-4-2-6-22(60-42-38(54)36(52)32(48)24(12-44)62-42)30(16)34(50)28-18(26)8-14(40(57)58)10-20(28)46/h1-10,23-26,31-32,35-38,41-48,51-54H,11-12H2,(H,55,56)(H,57,58)/t23-,24-,25-,26+,31-,32-,35+,36+,37-,38-,41-,42-/m1/s1

Chave InChI: InChIKey=IPQVTOJGNYVQEO-AIFLABODSA-N

SMILES: O=C1C=2C([C@@](C=3C1=C(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C=CC3)([C@@]5(C=6C(C(=O)C=7C5=CC=CC7O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)=C(O)C=C(C(O)=O)C6)[H])[H])=CC(C(O)=O)=CC2O

Sinónimos:

• (9R,9'S)-5,5'-bis(beta-D-glucopyranosyloxy)-4,4'-dihydroxy-10,10'-dioxo-9,9',10,10'-tetrahydro-9,9'-bianthracene-2,2'-dicarboxylic acid
• (9R,9′S)-5,5′-Bis(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)-9,9′,10,10′-tetrahydro-4,4′-dihydroxy-10,10′-dioxo[9,9′-bianthracene]-2,2′-dicarboxylic acid
• Nsc 112930
• Unii-F887D1637W
• [9,9′-Bianthracene]-2,2′-dicarboxylic acid, 5,5′-bis(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)-9,9′,10,10′-tetrahydro-4,4′-dihydroxy-10,10′-dioxo-, (9R,9′S)-
• [9,9′-Bianthracene]-2,2′-dicarboxylic acid, 5,5′-bis(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)-9,9′,10,10′-tetrahydro-4,4′-dihydroxy-10,10′-dioxo-, (R*,S*)-
• [9,9′-Bianthracene]-2,2′-dicarboxylic acid, 5,5′-bis(β-D-glucopyranosyloxy)-9,9′,10,10′-tetrahydro-4,4′-dihydroxy-10,10′-dioxo-, (R*,S*)-
• Sennoside B
• (9R,9′S)-5,5′-Bis(β-D-glucopyranosyloxy)-9,9′,10,10′-tetrahydro-4,4′-dihydroxy-10,10′-dioxo[9,9′-bianthracene]-2,2′-dicarboxylic acid
• [9,9′-Bianthracene]-2,2′-dicarboxylic acid, 5,5′-bis(β-D-glucopyranosyloxy)-9,9′,10,10′-tetrahydro-4,4′-dihydroxy-10,10′-dioxo-, (9R,9′S)-
• SENNIDINE B(RG)
• Sennoside B std.
• SENNOSIDE B WITH HPLC
• (9S,9'R)-5,5'-Bis(β-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo-9,9'-bianthracene-2,2'-dicarboxylic acid
• PURSENNIDE
• (9S)-9-[(9R)-2-Carboxy-4-hydroxy-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracen-9-yl]-4-hydroxy-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracene-2-carboxylic acid
• SENNOSIDE B hplc
• SENNOSIDE B(SH)
• [9,9'-Bianthracene]-2,2'-dicarboxylicacid,5,5'-bis(β-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo-,(9R,9'S)-
• (9S)-9-[(9R)-2-carboxy-4-hydroxy-10-oxo-5-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracen-9-yl]-4-hydroxy-10-oxo-5-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracene-2-carboxylic acid
• 9,9-Bianthracene-2,2-dicarboxylic acid, 5,5-bis(.beta.-D-glucopyranosyloxy)-9,9,10,10-tetrahydro-4,4-dihydroxy-10,10-dioxo-, (9R,9S)-
• SENNOSIDE B(P)
• SENNOSIDE B 96.5+%
• GLYSENNIDE

Sennoside B

CAS: 128-57-4

Sennoside B analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Fórmula: C₄₂H₃₈O₂₀

Pureza: (HPLC) ≥97%

Cor e Forma: Powder

Peso molecular: 862.75

Ref: 11-0457S

SENNOSIDE B CRS

CAS: 128-57-4

SENNOSIDE B CRS

Ref: 41-Y0002143

Sennoside B

CAS: 128-57-4

Other glycosides, natural or reproduced by synthesis, and their salts, ethers, esters and other derivatives

Fórmula: C₄₂H₃₈O₂₀

Cor e Forma: Yellow Powder

Peso molecular: 862.19564

Ref: 45-1612029

[9,9'-Bianthracene]-2,2'-dicarboxylic acid, 5,5'-bis(β-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo-, (9R,9'S)-

CAS: 128-57-4

Fórmula: C₄₂H₃₈O₂₀

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 862.7391

Ref: IN-DA000XNT

Sennoside B

CAS: 128-57-4

(9R,9'S)-4,4'-Dihydroxy-10,10'-dioxo-5,5'-bis(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-9,9',10,10'-tetrahydro-[9,9'-bianthracene]-2,2'-dicarboxylic acid

Fórmula: C₄₂H₃₈O₂₀

Pureza: 98%

Peso molecular: 862.74

Ref: IN-DG31711

Sennoside B

CAS: 128-57-4

Sennoside B

Fórmula: C₄₂H₃₈O₂₀

Pureza: ≥90%

Peso molecular: 862.74

Ref: 54-BUP00060

Sennoside B

CAS: 128-57-4

Fórmula: C₄₂H₃₈O₂₀

Pureza: ≥ 98.0%

Cor e Forma: Yellow powder

Peso molecular: 862.74

Ref: 7W-GC2469

Sennoside B

CAS: 128-57-4

Sennoside B

Pureza: 97%

Peso molecular: 862.74g/mol

Ref: 54-OR1023616

Sennoside B

CAS: 128-57-4

Fórmula: C₄₂H₃₈O₂₀

Pureza: >95.0%(HPLC)

Cor e Forma: White to Yellow to Yellow green powder to crystal

Peso molecular: 862.75

Ref: 3B-E1546

Sennoside B

CAS: 128-57-4

Fórmula: C₄₂H₃₈O₂₀

Pureza: 95%~99%

Peso molecular: 862.746

Ref: BP-BP1293

Sennoside B

CAS: 128-57-4

Fórmula: C₄₂H₃₈O₂₀

Peso molecular: 862.75

Ref: 4Z-S-078004

Sennoside B

CAS: 128-57-4

Sennoside B is an anthranoid. Anthranoid derivatives are used all over the world as a treatment for constipation.

Fórmula: C₄₂H₃₈O₂₀

Pureza: 92.85% - 98.92%

Cor e Forma: Light Yellow Crystal

Peso molecular: 862.74

Ref: TM-T2734

Sennoside B

CAS: 128-57-4

Natural glycoside

Fórmula: C₄₂H₃₈O₂₀

Pureza: ≥ 90.0 % (HPLC)

Cor e Forma: Powder

Peso molecular: 862.75

Ref: 5G-89277

Sennoside B

CAS: 128-57-4

Fórmula: C₄₂H₃₈O₂₀

Peso molecular: 862.75

Ref: ST-EA-CP-S57002

Sennoside B

CAS: 128-57-4

Fórmula: C₄₂H₃₈O₂₀

Cor e Forma: Neat

Peso molecular: 862.74

Ref: TR-S258810

Sennoside B

CAS: 128-57-4

Sennoside B is a natural laxative derived from the leaves and pods of senna plants, specifically Cassia angustifolia and Cassia acutifolia. As an anthraquinone glycoside, its structure comprises a sugar moiety linked to an aglycone, which is responsible for its pharmacological activity. The mode of action of Sennoside B involves its biotransformation by gut bacteria in the colon, where it is converted into its active form, rhein anthrone. This active metabolite stimulates the mucosal lining of the colon and alters electrolyte transport across the intestinal epithelium. The result is increased peristaltic contractions and an augmented influx of water into the colon, leading to bowel movement facilitation.

Fórmula: C₄₂H₃₈O₂₀

Pureza: Min. 98 Area-%

Cor e Forma: Powder

Peso molecular: 862.74 g/mol

Ref: 3D-MS08137

Sennoside B RS

CAS: 128-57-4

Cor e Forma: Yellow Solid Crystals To Powder

Ref: 2K-1078000021