CAS 131189-57-6

Cornusídeo

Descrição:

Cornusídeo, com o número CAS 131189-57-6, é um composto natural derivado principalmente das espécies de Cornus, particularmente da árvore de dogwood. É classificado como um glicosídeo flavonoide, o que significa que consiste em uma parte flavonoide ligada a uma molécula de açúcar. Cornusídeo é conhecido por suas potenciais propriedades farmacológicas, incluindo efeitos anti-inflamatórios, antioxidantes e neuroprotetores. Sua estrutura normalmente apresenta uma espinha dorsal flavonoide, que contribui para sua atividade biológica e interação com várias vias celulares. Pesquisas indicaram que Cornusídeo pode desempenhar um papel na modulação do estresse oxidativo e da inflamação, tornando-o de interesse no contexto de várias condições de saúde. Além disso, sua presença na medicina tradicional destaca sua importância histórica e potenciais aplicações terapêuticas. No entanto, mais estudos são necessários para elucidar completamente seus mecanismos de ação e eficácia em ambientes clínicos. Assim como muitos compostos naturais, as características específicas, incluindo solubilidade e estabilidade, podem variar com base nas condições ambientais e no método de extração.

Fórmula: C₂₄H₃₀O₁₄

InChI: InChI=1S/C24H30O14/c1-3-11-12(4-5-35-21(32)10-6-14(26)17(28)15(27)7-10)13(22(33)34-2)9-36-23(11)38-24-20(31)19(30)18(29)16(8-25)37-24/h3,6-7,9,11-12,16,18-20,23-31H,1,4-5,8H2,2H3

Chave InChI: InChIKey=SMTKSCGLXONVGL-UHFFFAOYSA-N

SMILES: C(COC(=O)C1=CC(O)=C(O)C(O)=C1)C2C(C=C)C(OC3OC(CO)C(O)C(O)C3O)OC=C2C(OC)=O

Sinónimos:

• 2H-Pyran-5-carboxylic acid, 3-ethenyl-2-(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)-3,4-dihydro-4-[2-[(3,4,5-trihydroxybenzoyl)oxy]ethyl]-, methyl ester, (2S,3R,4S)-
• 2H-Pyran-5-carboxylic acid, 3-ethenyl-2-(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)-3,4-dihydro-4-[2-[(3,4,5-trihydroxybenzoyl)oxy]ethyl]-, methyl ester, [2S-(2α,3β,4β)]-
• Cornuside I
• Methyl (2R,3S,4R)-3-ethenyl-4-[2-(3,4,5-trihydroxybenzoyl)oxyethyl]-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,4-dihydro-2H-pyran-5-carboxylate
• methyl (2R,3S,4R)-3-ethenyl-2-(beta-D-glucopyranosyloxy)-4-{2-[(3,4,5-trihydroxybenzoyl)oxy]ethyl}-3,4-dihydro-2H-pyran-5-carboxylate
• 2H-Pyran-5-carboxylic acid, 3-ethenyl-2-(β-D-glucopyranosyloxy)-3,4-dihydro-4-[2-[(3,4,5-trihydroxybenzoyl)oxy]ethyl]-, methyl ester, [2S-(2α,3β,4β)]-
• Cornuside
• 2H-Pyran-5-carboxylic acid, 3-ethenyl-2-(β-D-glucopyranosyloxy)-3,4-dihydro-4-[2-[(3,4,5-trihydroxybenzoyl)oxy]ethyl]-, methyl ester, (2S,3R,4S)-

Comuside

CAS: 131189-57-6

Comuside

Fórmula: C₂₄H₃₀O₁₄

Pureza: 99%

Peso molecular: 542.48659

Ref: 54-BISN0277

Cornuside

CAS: 131189-57-6

Fórmula: C₂₄H₃₀O₁₄

Peso molecular: 542.49

Ref: 7W-GK2384

Cornuside

CAS: 131189-57-6

Cornuside

Fórmula: C₂₄H₃₀O₁₄

Pureza: ≥98%

Peso molecular: 542.49

Ref: 54-BUP08489

Comuside

CAS: 131189-57-6

Fórmula: C₂₄H₃₀O₁₄

Pureza: 99%

Peso molecular: 542.4866

Ref: IN-DA000VNU

Cornuside (Standard)

CAS: 131189-57-6

Cornuside (Standard) is a reference standard for research and analysis in studies involving Cornuside. 1. Cornuside (Comuside) has immunomodulatory activity . 2. Cornuside suppresses expression levels of cytokine-induced proinflammatory and adhesion molecules in the human endothelial cells. 3. Cornuside can treat myocardial I/R and protect the liver from CCl4-induced acute hepatotoxicity, by reducing oxidative stress and suppressing inflammatory responses. 4. Cornuside has anti-inflammatory activity by downregulations of iNOS and COX-2 due to NF-κB inhibition as well as the negative regulation of ERK1/2, p38, and JNK1/2 phosphorylations in RAW 264.7 cells. 5. Cornuside has protective potential against cerebral ischemic injury, may be due to the suppression of intracellular Ca(2+) elevation and caspase-3 activity, and improvements in mitochondrial energy metabolism and antioxidant properties.

Fórmula: C₂₄H₃₀O₁₄

Peso molecular: 542.4866

Ref: TM-TMSM-2765

Cornuside

CAS: 131189-57-6

Fórmula: C₂₄H₃₀O₁₄

Pureza: 95%~99%

Peso molecular: 542.49

Ref: BP-BP0394

Cornuside

CAS: 131189-57-6

Cornuside boosts immunity, reduces inflammation, protects heart and liver, and guards against brain injury by modulating stress responses.

Fórmula: C₂₄H₃₀O₁₄

Pureza: 99.86% - >99.99%

Cor e Forma: Solid

Peso molecular: 542.4866

Ref: TM-T4S2326

Cornuside

CAS: 131189-57-6

(2S,3R,4S)-3-Ethenyl-2-(β-D-glucopyranosyloxy)-3,4-dihydro-4-[2-[(3,4,5-trihydroxybenzoyl)oxy]ethyl]-2H-pyran-5-carboxylic acid methyl ester

Fórmula: C₂₄H₃₀O₁₄

Pureza: 99%

Peso molecular: 542.49

Ref: IN-DG01301000

Cornuside

CAS: 131189-57-6

Natural glycoside

Fórmula: C₂₄H₃₀O₁₄

Pureza: ≥ 90.0 % (HPLC)

Cor e Forma: Powder

Peso molecular: 542.49

Ref: 5G-83331

Cornuside

CAS: 131189-57-6

Cornuside is a natural compound that is found in the fruits of Cornus. It is a dihydrochalcone, which has been shown to have hypoglycemic effects and inhibit the activity of 5-hmf. Cornuside also inhibits the enzyme activities involved in energy metabolism, such as glucose-6-phosphate dehydrogenase and hexokinase. It has also been shown to have genotoxic properties and induce DNA damage. Cornuside may be useful for treating diabetes or cancer, but further research needs to be done before this can be confirmed.

Fórmula: C₂₄H₃₀O₁₄

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 542.49 g/mol

Ref: 3D-MC33273

Cornuside

CAS: 131189-57-6

Fórmula: C₂₄H₃₀O₁₄

Peso molecular: 542.5

Ref: BE-RMT12842