CAS 1353020-85-5

Fórmula: C24H23N3O5

InChI: InChI=1S/C24H23N3O5/c1-13(28)10-26-11-21(29)27-18(24(26)30)9-16-15-4-2-3-5-17(15)25-22(16)23(27)14-6-7-19-20(8-14)32-12-31-19/h2-8,13,18,23,25,28H,9-12H2,1H3/t13?,18-,23-/m1/s1

Chave InChI: YGRCGCUDAOLEEX-QMWSHBGFSA-N

SMILES: CC(CN1CC(=O)N2[C@@H](C1=O)CC3=C([C@H]2C4=CC5=C(C=C4)OCO5)NC6=CC=CC=C36)O

2-Hydroxypropylnortadalafil (Standard)

CAS: 1353020-85-5

2-Hydroxypropylnortadalafil (Standard) is a reference standard of 2-Hydroxypropylnortadalafil intended for quantitative analysis, quality control, and related biochemical research applications.

Fórmula: C₂₄H₂₃N₃O₅

Cor e Forma: Solid

Peso molecular: 433.46

Ref: TM-TMSM-4875

2-Hydroxypropyl Nortadalafil (Mixture of Diastereomers)

CAS: 1353020-85-5

Fórmula: C₂₄H₂₃N₃O₅

Cor e Forma: White To Off-White Solid

Peso molecular: 433.46

Ref: 4Z-T-1029

Nortadalafil-N-(2-hydroxy)propyl

CAS: 1353020-85-5

Fórmula: C₂₄H₂₃N₃O₅

Cor e Forma: Neat

Peso molecular: 433.46

Ref: 04-C15651925

2-Hydroxypropyl Nortadalafil (Mixture of Diastereomers)

Produto Controlado

CAS: 1353020-85-5

Applications 2-Hydroxypropyl Nortadalafil is a derivative of Tadalafil (T004500), which is used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor.
References Carrier, S., et al.: Can. J. Urol., 10(1), 12 (2003), Doggrell, S.A., et al.: Expert Opin. Pharmacother., 6, 75 (2005), Forgue, S.T., et al.: Br. J. Clin. Pharmacol., 61, 280 (2005), Toomey, V. et al.: J. Pharm. Biomed. Anal., 59, 50 (2012);

Fórmula: C₂₄H₂₃N₃O₅

Cor e Forma: Neat

Peso molecular: 433.46

Ref: TR-H952705

2-Hydroxypropylnortadalafil in Methanol

CAS: 1353020-85-5

Methanol

Ref: BE-BePure-27401XM-100

2-Hydroxypropyl-d6 Nortadalafil

Produto Controlado

CAS: 1353020-85-5

Fórmula: C₂₄D₆H₁₇N₃O₅

Cor e Forma: Neat

Peso molecular: 439.493

Ref: TR-H952707

2-Hydroxypropyl Nortadalafil (Mixture of Diastereomers)

CAS: 1353020-85-5

Fórmula: C₂₄H₂₃N₃O₅

Peso molecular: 433.46

Ref: ST-EA-CP-T31092

Nortadalafil-N-(2-hydroxy)propyl

CAS: 1353020-85-5

Nortadalafil-N-(2-hydroxy)propyl is a chemotherapeutic agent, which is synthesized through the chemical modification of tadalafil. It is characterized as a small-molecule inhibitor, derived from the structural alteration of the well-known phosphodiesterase type 5 (PDE5) inhibitor. The mechanism of action involves the attenuation of PDE5 activity, leading to increased levels of cyclic guanosine monophosphate (cGMP) within targeted cellular pathways. This elevation in cGMP concentration results in vasodilation and increased blood flow, primarily investigated within the context of vascular and erectile tissue.

Fórmula: C₂₄H₂₃N₃O₅

Pureza: Min. 95%

Peso molecular: 433.5 g/mol

Ref: 3D-DEC02085