CAS 1354690-24-6

Fórmula: C21H25F3N6O2

InChI: InChI=1S/C21H25F3N6O2/c1-3-18(31)30-6-4-13(10-30)28-19-15-11-29(7-5-17(15)26-12-27-19)14-8-16(21(22,23)24)20(32-2)25-9-14/h8-9,12-13H,3-7,10-11H2,1-2H3,(H,26,27,28)/t13-/m0/s1

Chave InChI: MWKYMZXCGYXLPL-ZDUSSCGKSA-N

SMILES: CCC(=O)N1CC[C@@H](C1)NC2=NC=NC3=C2CN(CC3)C4=CC(=C(N=C4)OC)C(F)(F)F

Leniolisib

CAS: 1354690-24-6

Fórmula: C₂₁H₂₅F₃N₆O₂

Pureza: 99%

Cor e Forma: Solid

Peso molecular: 450.4574

Ref: IN-DA01EN5I

Leniolisib

CAS: 1354690-24-6

Leniolisib

Fórmula: C₂₁H₂₅F₃N₆O₂

Pureza: ≥98%

Peso molecular: 450.46

Ref: 54-BUP04192

Leniolisib

CAS: 1354690-24-6

Fórmula: C₂₁H₂₅F₃N₆O₂

Peso molecular: 450.47

Ref: 4Z-L-249001

(S)-1-(3-((6-(6-Methoxy-5-(Trifluoromethyl)Pyridin-3-Yl)-5,6,7,8-Tetrahydropyrido[4,3-D]Pyrimidin-4-Yl)Amino)Pyrrolidin-1-Yl)Propan-1-One

CAS: 1354690-24-6

(S)-1-(3-((6-(6-Methoxy-5-(Trifluoromethyl)Pyridin-3-Yl)-5,6,7,8-Tetrahydropyrido[4,3-D]Pyrimidin-4-Yl)Amino)Pyrrolidin-1-Yl)Propan-1-One

Fórmula: C₂₁H₂₅F₃N₆O₂

Pureza: 99%

Peso molecular: 450.46

Ref: 54-PC108439

Leniolisib

CAS: 1354690-24-6

(S)-1-(3-((6-(6-Methoxy-5-(trifluoromethyl)pyridin-3-yl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl)amino)pyrrolidin-1-yl)propan-1-one

Fórmula: C₂₁H₂₅F₃N₆O₂

Pureza: 99%

Peso molecular: 450.46

Ref: IN-DG766644

Leniolisib

CAS: 1354690-24-6

Leniolisib (CDZ173) (CDZ173) is a potent and selective PI3Kδ inhibitor (IC50: 11 nM).

Fórmula: C₂₁H₂₅F₃N₆O₂

Pureza: 99.88%

Cor e Forma: Solid

Peso molecular: 450.4574

Ref: TM-T5166

Leniolisib

CAS: 1354690-24-6

Leniolisib is a small molecule that inhibits the lipid kinase activity of the enzyme phosphatidylinositol 3-kinase (PI3K). This drug has been shown to have an anti-inflammatory effect in vitro, which may be due to its ability to inhibit the secretion of inflammatory mediators and cytokines from activated macrophages. Leniolisib also has been shown to have immunosuppressive properties, which may be due to its ability to induce apoptosis in lymphocytes. This drug also has been shown to suppress the growth of tumor cells in vitro by inhibiting cell cycle progression at G1 phase and inducing senescence. This drug may have potential as a therapeutic for autoimmune diseases such as rheumatoid arthritis and multiple sclerosis.

Fórmula: C₂₁H₂₅F₃N₆O₂

Pureza: Min. 95%

Peso molecular: 450.46 g/mol

Ref: 3D-EEC69024

Leniolisib

CAS: 1354690-24-6

Pureza: 99%

Peso molecular: 450.199

Ref: 10-F818675