CAS 1361224-53-4

Fórmula: C21H20F6N4O3S

InChI: InChI=1S/C21H20F6N4O3S/c1-2-3-16-13-30(35(33,34)17-8-9-18(28)29-12-17)10-11-31(16)15-6-4-14(5-7-15)19(32,20(22,23)24)21(25,26)27/h4-9,12,16,32H,10-11,13H2,1H3,(H2,28,29)/t16-/m0/s1

Chave InChI: SIFKNECWLVONIH-INIZCTEOSA-N

SMILES: CC#C[C@H]1CN(CCN1C2=CC=C(C=C2)C(C(F)(F)F)(C(F)(F)F)O)S(=O)(=O)C3=CN=C(C=C3)N

AMG-3969

CAS: 1361224-53-4

AMG-3969

Fórmula: C₂₁H₂₀F₆N₄O₃S

Pureza: 99.5%

Peso molecular: 522.46

Ref: 54-BUP04929

AMG-3969

CAS: 1361224-53-4

AMG-3969

Fórmula: C₂₁H₂₀F₆N₄O₃S

Pureza: 99%

Cor e Forma: Solid

Peso molecular: 522.46391

Ref: 54-BISN0048

AMG-3969

CAS: 1361224-53-4

AMG-3969 is an effective glucokinase-glucokinase regulatory protein interaction (GK-GKRP) disruptor (IC50: 4 nM).

Fórmula: C₂₁H₂₀F₆N₄O₃S

Pureza: 99.65%

Cor e Forma: Solid

Peso molecular: 522.464

Ref: TM-TQ0055

AMG3969

CAS: 1361224-53-4

(S)-2-(4-(4-((6-Aminopyridin-3-yl)sulfonyl)-2-(prop-1-yn-1-yl)piperazin-1-yl)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol

Fórmula: C₂₁H₂₀F₆N₄O₃S

Pureza: 99%

Peso molecular: 522.46

Ref: IN-DG00799101

AMG-3969

CAS: 1361224-53-4

AMG-3969 is a piperazine derivative with a potent profile that inhibits the gluconeogenic enzymes. It has been shown to have regulatory effects on pancreatic cells and animals in vitro and in vivo. AMG-3969 is also effective at inhibiting uptake of glucose from the blood by cells in vitro, which may lead to antidiabetic effects. It is also synthesized using an asymmetric synthesis, making it a unique molecule that has not been seen before. The safety profile of AMG-3969 has been demonstrated in preclinical studies.

Fórmula: C₂₁H₂₀F₆N₄O₃S

Pureza: Min. 95%

Peso molecular: 522.46 g/mol

Ref: 3D-LEC22453