CAS 13710-19-5

ácido tolfenâmico

Descrição:

ácido tolfenâmico é um medicamento anti-inflamatório não esteroidal (AINE) que pertence à classe dos derivados do ácido antranílico. É utilizado principalmente por suas propriedades analgésicas e anti-inflamatórias, tornando-o eficaz no tratamento da dor e da inflamação associadas a várias condições. A estrutura química de ácido tolfenâmico apresenta um grupo ácido carboxílico e um anel aromático, que contribuem para sua atividade farmacológica. Exibe solubilidade moderada em água e é mais solúvel em solventes orgânicos, refletindo sua natureza lipofílica. ácido tolfenâmico atua inibindo as enzimas ciclooxigenases (COX), reduzindo assim a síntese de prostaglandinas, que são mediadores da inflamação e da dor. A substância é tipicamente administrada por via oral e é conhecida por seu início de ação relativamente rápido. Além disso, foi estudada para uso potencial na medicina veterinária, particularmente no tratamento da dor em animais. Assim como outros AINEs, pode ter efeitos colaterais, incluindo distúrbios gastrointestinais, e deve ser usada com cautela em indivíduos com certas condições de saúde.

Fórmula: C₁₄H₁₂ClNO₂

InChI: InChI=1/C14H12ClNO2/c1-9-11(15)6-4-8-12(9)16-13-7-3-2-5-10(13)14(17)18/h2-8,16H,1H3,(H,17,18)

Chave InChI: InChIKey=YEZNLOUZAIOMLT-UHFFFAOYSA-N

SMILES: N(C1=C(C(O)=O)C=CC=C1)C2=C(C)C(Cl)=CC=C2

Sinónimos:

• 1,2-Distearoyl-sn-glycero-3-phosphocholine, DSPC
• 2 (3-Chloro-2-Methylanilino)Benzoic Acid
• 2-((3-Chloro-2-Methylphenyl)Amino)-Benzoicaci
• 2-(3-Chloro-O-Toluidino)Benzoic Acid
• 2-[(3-Chloro-2-Methylphenyl)Amino]Benzoic Acid
• 2-[(4-Chloro-3-Methylphenyl)Amino]Benzoic Acid
• Anthranilic acid, N-(3-chloro-o-tolyl)-
• Benzoic acid, 2-[(3-chloro-2-methylphenyl)amino]-
• Clotam
• Gea 6414
• Gea6414
• Labotest-Bb Lt00772313
• Migea
• N-(2-Methyl-3-chlorophenyl)anthranilic acid
• N-(3-Chloro-o-tolyl)anthranilic acid
• N-(3-Chloro-ortho-tolyl) anthranilic acid
• Tolfedine
• Tolfenamate
• Tolfine
• n-(3-chloro-o-tolyl)-anthranilicacid
• Tolfenamic
• n-(3-chloro-o-tolyl)-anthranilicaci
• TOLFENAMIC ACID
• N-(3-CHLORO-2-METHYLPHENYL)ANTHRANILIC ACID
• 2 (3-Chloro-2-methylanilino)benzoic acid, 2-([3-Chloro-2-methylphenyl]amino)benzoic acid
• n-(2-methyl-3-chlorophenyl)anthranilicacid

Tolfenamic Acid

CAS: 13710-19-5

Fórmula: C₁₄H₁₂ClNO₂

Pureza: >97.0%(T)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 261.71

Ref: 3B-C2064

Tolfenamic acid, 99+%

CAS: 13710-19-5

Tolfenamic acid is a non-steroidal anti-inflammatory agent. It interferes with synthesis of -amyloid precursor protein, and thus A peptides, by promoting degradation of an essential transcription factor. It inhibits fMLP- and A23187-induced Ca2+ influx in human PMNL with an IC50 value of approximate

Fórmula: C₁₄H₁₂ClNO₂

Pureza: 99+%

Peso molecular: 261.71

Ref: 02-J61256

TOLFENAMIC ACID CRS

CAS: 13710-19-5

TOLFENAMIC ACID CRS

Fórmula: C₁₄H₁₂ClNO₂

Cor e Forma: Added Modified

Peso molecular: 261.7036

Ref: 41-Y0000154

2-[(3-chloro-2-methylphenyl)amino]benzoic acid

CAS: 13710-19-5

Fórmula: C₁₄H₁₂ClNO₂

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 261.7036

Ref: IN-DA003SAR

Tolfenamic Acid

CAS: 13710-19-5

Tolfenamic Acid (GEA 6414) is one of the class of non-steroidal anti-inflammatory drugs (NSAIDs). It is used to treat the symptoms of migraine.

Fórmula: C₁₄H₁₂ClNO₂

Pureza: 99.74% - 99.95%

Cor e Forma: White Solid

Peso molecular: 261.70

Ref: TM-T0784

Tolfenamic Acid

CAS: 13710-19-5

Fórmula: C₁₄H₁₂ClNO₂

Cor e Forma: White To Off-White Solid

Peso molecular: 261.71

Ref: 4Z-T-962

2-((3-Chloro-2-Methylphenyl)Amino)Benzoic Acid

CAS: 13710-19-5

2-((3-Chloro-2-Methylphenyl)Amino)Benzoic Acid

Fórmula: C₁₄H₁₂ClNO₂

Pureza: 98%

Peso molecular: 261.7

Ref: 54-OR1009617

Tolfenamic Acid

CAS: 13710-19-5

Tolfenamic Acid

Fórmula: C₁₄H₁₂ClNO₂

Pureza: ≥98%

Peso molecular: 261.7

Ref: 54-BUP17586

Tolfenamic-d4 Acid (Benzoic-3,4,5,6-d4)

CAS: 1246820-82-5, 13710-19-5

Pureza: 98 atom % D

Peso molecular: 265.73

Ref: 3U-D7725

Tolfenamic acid

Produto Controlado

CAS: 13710-19-5

Fórmula: C₁₄H₁₂ClNO₂

Cor e Forma: Off-White

Peso molecular: 261.70

Ref: 04-C17591000

Tolfenamic acid 1000 µg/mL in Acetonitrile

Produto Controlado

CAS: 13710-19-5

Fórmula: C₁₄H₁₂ClNO₂

Cor e Forma: Colourless

Peso molecular: 261.70

Ref: 04-A17591000AL-1000

Tolfenamic Acid

CAS: 13710-19-5

Cor e Forma: Neat

Ref: 61-FOR3395.00

Tolfenamic Acid

Produto Controlado

CAS: 13710-19-5

Fórmula: C₁₄H₁₂ClNO₂

Cor e Forma: Off-White

Peso molecular: 261.70

Ref: 86-MM3395.00

Tolfenamic Acid

Produto Controlado

CAS: 13710-19-5

Applications Non-steroidal anti-inflammatory drugs (NSAIDs). A derivative of anthranilic acid, related structurally to Mefenamic and Flufenamic acids. Anti-inflammatory, analgesic.
References Pentikaeinen, P., et al.: Eur. J. Clin. Pharmacol., 19, 359 (1981), Bundscherer, A., et al.: Oncol. Rep., 19, 547 (2008), Elwood, P., et al.: Lancet, 373, 1301 (2009),

Fórmula: C₁₄H₁₂ClNO₂

Cor e Forma: Neat

Peso molecular: 261.7

Ref: TR-T535300

Tolfenamic acid

CAS: 13710-19-5

Ref: BE-BePure-26071

Tolfenamic acid in Methanol

CAS: 13710-19-5

Methanol

Ref: BE-BePure-26071XM-100

Tolfenamic Acid

CAS: 13710-19-5

2-((3-Chloro-2-methylphenyl)amino)benzoic acid

Fórmula: C₁₄H₁₂ClNO₂

Pureza: 98%

Peso molecular: 261.7

Ref: IN-DG154339

Tolfenamic Acid

CAS: 13710-19-5

Fórmula: C₁₄H₁₂ClNO₂

Pureza: 97%

Cor e Forma: No data available.

Peso molecular: 261.71

Ref: 10-F519604

Tolfenamic Acid

CAS: 13710-19-5

Tolfenamic acid is a non-steroidal anti-inflammatory drug that has been shown to inhibit the MCL-1 protein, which is involved in the regulation of programmed cell death. It has been used for the treatment of bowel disease and can be given orally or rectally. Tolfenamic acid may be effective against inflammatory bowel diseases such as ulcerative colitis and Crohn's disease. Tolfenamic acid binds to anionic sites on the matrix of cartilage and inhibits the production of prostaglandin E2 by inhibiting cyclooxygenase activity. Tolfenamic acid has also been shown to reduce pain by inhibiting the enzyme COX-2, which is associated with inflammation. The drug also has a strong effect on human polymorphonuclear leukocytes (PMN).

Fórmula: C₁₄H₁₂ClNO₂

Pureza: Min. 97%

Cor e Forma: Powder

Peso molecular: 261.7 g/mol

Ref: 3D-FT28306

Tolfenamic acid

CAS: 13710-19-5

Fórmula: C₁₄H₁₂ClNO₂

Peso molecular: 261.71

Ref: ST-EA-CP-T88000