CAS 13734-41-3
:Boc-L-valina
Descrição:
Boc-L-valina, ou tert-butoicocarbonila-L-valina, é uma forma protegida do aminoácido valina, comumente utilizada na síntese de peptídeos e na química orgânica. Apresenta um grupo tert-butoicocarbonila (Boc), que serve como um grupo protetor para a funcionalidade amino, permitindo reações seletivas sem interferir com o grupo amino. O composto é tipicamente um sólido cristalino branco a off-white e é solúvel em solventes orgânicos como diclorometano e dimetilformamida, mas menos solúvel em água. Boc-L-valina é caracterizado por sua quiralidade, pois contém um centro quiral no carbono alfa, tornando-se um enantiômero L. Essa propriedade é crucial em sistemas biológicos e aplicações farmacêuticas, onde a estereoisomeria específica pode influenciar significativamente a atividade e eficácia. O composto é estável em condições laboratoriais padrão, mas pode ser hidrolisado em condições ácidas ou básicas, liberando o aminoácido livre valina. Suas aplicações se estendem à síntese de peptídeos, onde o grupo Boc pode ser removido em condições ácidas suaves, facilitando reações posteriores.
Fórmula:C10H19NO4
InChI:InChI=1S/C10H19NO4/c1-6(2)7(8(12)13)11-9(14)15-10(3,4)5/h6-7H,1-5H3,(H,11,14)(H,12,13)/t7-/m0/s1
Chave InChI:InChIKey=SZXBQTSZISFIAO-ZETCQYMHSA-N
SMILES:[C@H](NC(OC(C)(C)C)=O)(C(C)C)C(O)=O
Sinónimos:- (2S)-2-(tert-Butoxycarbonylamino)-3-methylbutanoic acid
- (2S)-2-[(tert-butoxycarbonyl)amino]-3-methylbutanoate
- (2S)-2-[[(1,1-Dimethylethoxy)carbonyl]amino]-3-methylbutanoic acid
- (2S)-2-[[(tert-Butoxy)carbonyl]amino]-3-methylbutanoic acid
- (2S)-3-Methyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid
- (S)-2-(Boc-Amino)-3-Methylbutyric Acid
- (S)-2-(tert-Butoxycarbonylamino)-3-methylbutanoic acid
- (S)-Boc-Valine
- (S)-N-tert-Butoxycarbonylvaline
- <span class="text-smallcaps">L</span>-Valine, N-[(1,1-dimethylethoxy)carbonyl]-
- BOC-valine
- Boc-<span class="text-smallcaps">L</span>-Val
- Boc-<span class="text-smallcaps">L</span>-valine
- Boc-L-Valine
- Boc-Val-OH
- Boc-l-Val-OH
- L-Valine, N-[(1,1-dimethylethoxy)carbonyl]-
- N-(tert-butoxycarbonyl)-D-valine
- N-(tert-butoxycarbonyl)-L-valine
- N-(tert-butoxycarbonyl)valine
- N-BOC-<span class="text-smallcaps">L</span>-valine
- N-BOC-valine
- N-Boc-L-Valine
- N-[(1,1-Dimethylethoxy)carbonyl]-<span class="text-smallcaps">L</span>-valine
- N-[(1,1-Dimethylethoxy)carbonyl]-L-valine
- N-[(terc-butoxi)carbonil]-L-valina
- N-[(tert-Butoxy)carbonyl]-L-valin
- N-tert-Butoxycarbonyl-<span class="text-smallcaps">L</span>-valine
- N-tert-Butoxycarbonyl-<span class="text-smallcaps">L</span>-valine vinyl ester
- N-tert-Butoxycarbonylvaline
- N-tert-Butyloxycarbonyl-<span class="text-smallcaps">L</span>-valine
- N-tert-Butyloxycarbonyl-L-valine
- N-tert-Butyloxycarbonylvaline
- N-α-tert-Butoxycarbonyl-<span class="text-smallcaps">L</span>-valine
- N-α-tert-Butoxycarbonyl-L-valine
- Nsc 197197
- Valine, N-carboxy-, N-tert-butyl ester, <span class="text-smallcaps">L</span>-
- Valine, N-carboxy-, N-tert-butyl ester, L-
- t-Butoxycarbonyl-<span class="text-smallcaps">L</span>-valine
- t-Butoxycarbonyl-L-valine
- tert-Butoxycarbonyl-<span class="text-smallcaps">L</span>-valine
- Ver mais sinónimos
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Foram encontrados 14 produtos.
N-(tert-Butoxycarbonyl)-L-valine
CAS:Fórmula:C10H19NO4Pureza:>99.0%(T)Cor e Forma:White to Almost white powder to crystalPeso molecular:217.27N-Boc-L-valine, 98+%
CAS:N-Boc-L-valine is used in the multi-peptide synthesis and serves as the amino acid protection monomer. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa AesFórmula:C10H19NO4Pureza:98+%Cor e Forma:White, PowderPeso molecular:217.27N-t-butyloxycarbonyl-N-methyl-L-valine
CAS:Fórmula:C10H19NO4Pureza:97%Cor e Forma:SolidPeso molecular:217.2622Boc-Val-OH
CAS:M03340 - Boc-Val-OH
Fórmula:C10H19NO4Pureza:98%Cor e Forma:Solid, Powder or Crystalline Powder or SolidPeso molecular:217.265N-(tert-Butoxycarbonyl)-L-valine
CAS:N-(tert-Butoxycarbonyl)-L-valineFórmula:C10H19NO4Pureza:99%Cor e Forma:SolidPeso molecular:217.26215BOC-L-Valine extrapure, 99%
CAS:Fórmula:C10H19NO4Pureza:min. 99%Cor e Forma:White to off-white, Crystalline powderPeso molecular:217.30Boc-L-Valine
CAS:Produto ControladoApplications Boc-L-Valine is used in amino acid conjugates as proteasome inhibitors.
References Wan, S. et al.: Int. J. Mol. Med., 26, 447 (2010);Fórmula:C10H19NO4Cor e Forma:NeatPeso molecular:217.26Boc-Val-OH
CAS:Boc-Val-OH is a natural compound that belongs to the class of ferrocene fatty acid. It has been shown to have antimicrobial properties in cell culture and pharmacokinetic properties in rats. Boc-Val-OH is able to inhibit the activity of serine proteases, which are enzymes that break down proteins and amino acids within cells, as well as cyclopropavir, a virus inhibitor. This compound also has potent inhibitory activity against various microbial strains, including methicillin-resistant Staphylococcus aureus (MRSA) and Helicobacter pylori. Boc-Val-OH has been shown to have hepatoprotective effects in rats with liver damage.Fórmula:C10H19NO4Pureza:Min. 95%Peso molecular:217.26 g/molBoc-L-valine
CAS:Boc-L-Valine is a model system for the synthesis of peptides. This compound is synthesized in a liquid phase and then purified by column chromatography. It has an antimicrobial activity against Gram-positive bacteria such as Staphylococcus aureus and Escherichia coli, but not against Gram-negative bacteria such as Proteus vulgaris or Pseudomonas aeruginosa. Boc-L-Valine is also used to study the binding of inhibitors and ferrocenes.Fórmula:C10H19NO4Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:217.3 g/molBoc-Val-OH
CAS:Bachem ID: 4000426.
Fórmula:C10H19NO4Pureza:100.0%Cor e Forma:WhitePeso molecular:217.27
