CAS 1387560-01-1

Fórmula: C19H15ClF7N5O2

InChI: InChI=1S/C19H15ClF7N5O2/c1-16(7-34-17(2,15(28)32-16)19(25,26)27)13-10(21)3-4-11(30-13)31-14(33)12-9(20)5-8(6-29-12)18(22,23)24/h3-6H,7H2,1-2H3,(H2,28,32)(H,30,31,33)/t16-,17+/m0/s1

Chave InChI: PSBBWFNMHDUTRH-DLBZAZTESA-N

SMILES: C[C@]1(CO[C@@](C(=N1)N)(C)C(F)(F)F)C2=C(C=CC(=N2)NC(=O)C3=C(C=C(C=N3)C(F)(F)F)Cl)F

Umibecestat

CAS: 1387560-01-1

Umibecestat

Fórmula: C₁₉H₁₅ClF₇N₅O₂

Pureza: 99.5%

Peso molecular: 513.8

Ref: 54-BUP04670

N-(6-((3R,6R)-5-Amino-3,6-dimethyl-6-(trifluoromethyl)-3,6-dihydro-2H-1,4-oxazin-3-yl)-5-fluoropyridin-2-yl)-3-chloro-5-(trifluoromethyl)picolinamide

CAS: 1387560-01-1

Fórmula: C₁₉H₁₅ClF₇N₅O₂

Pureza: 99%

Cor e Forma: Solid

Peso molecular: 513.7965

Ref: IN-DA0201A1

Umibecestat

CAS: 1387560-01-1

N-(6-((3R,6R)-5-Amino-3,6-dimethyl-6-(trifluoromethyl)-3,6-dihydro-2H-1,4-oxazin-3-yl)-5-fluoropyridin-2-yl)-3-chloro-5-(trifluoromethyl)picolinamide

Fórmula: C₁₉H₁₅ClF₇N₅O₂

Pureza: 99%

Peso molecular: 513.8

Ref: IN-DG01139242

Umibecestat

CAS: 1387560-01-1

Umibecestat is a monoclonal antibody that binds to am-6494, an absorber of serotonin. It has been shown to have therapeutic effects on hyperproliferative diseases such as cancer and inflammatory bowel disease. Umibecestat is a potent inhibitor of the serotonin reuptake transporter and exhibits anti-inflammatory properties by inhibiting the production of proinflammatory cytokines. It also inhibits metabolic disorders such as diabetes mellitus type 2 and obesity. Umibecestat has been shown to be safe in Phase 2 clinical trials for patients with IBD.

Fórmula: C₁₉H₁₅ClF₇N₅O₂

Pureza: Min. 95%

Peso molecular: 513.8 g/mol

Ref: 3D-MFC56001

Umibecestat

CAS: 1387560-01-1

Umibecestat inhibits human and mouse BACE-1 (IC50: 11 nM & 10 nM), potentially for Alzheimer's research.

Fórmula: C₁₉H₁₅ClF₇N₅O₂

Pureza: 99.88%

Cor e Forma: Solid

Peso molecular: 513.797

Ref: TM-T13253