CAS 1401168-39-5

Kartogenin sodium

Fórmula: C₂₀H₁₅NO₃·Na

InChI: InChI=1S/C20H15NO3.Na/c22-19(17-8-4-5-9-18(17)20(23)24)21-16-12-10-15(11-13-16)14-6-2-1-3-7-14;/h1-13H,(H,21,22)(H,23,24);/q;+1/p-1

Chave InChI: LNDQCRAZLSOXTG-UHFFFAOYSA-M

SMILES: C1=CC=C(C=C1)C2=CC=C(C=C2)NC(=O)C3=CC=CC=C3C(=O)[O-].[Na+]

Sinónimos:

• Kartogenin sodium

Kartogenin sodium

CAS: 1401168-39-5

Kartogenin sodium

Fórmula: C₂₀H₁₅NNaO₃

Pureza: 95%

Peso molecular: 340.33

Ref: 54-OR1159780

Kartogenin sodium

CAS: 1401168-39-5

Pureza: 95%

Ref: IN-DA033G7E

Kartogenin sodium

CAS: 1401168-39-5

Kartogenin (KGN) sodium acts as an inducer of chondrogenic tissue formation (EC 50: 100 nM). It promotes chondrogenesis by binding to fibrin A, disrupting its interaction with the transcription factor core binding factor beta subunit (CBFβ), and modulating the CBFβ-RUNX1 transcriptional program. Additionally, Kartogenin sodium aids tendon-bone junction (TBJ) wound healing by stimulating collagen synthesis. It is extensively utilized in cell-free therapies for cartilage regeneration and protection, tendon-bone healing, wound healing, and limb development. The compound is also vital for cartilage repair, coordinating limb development, and osteoarthritis (OA) research [1] [2] [3] [4].

Fórmula: C₂₀H₁₄NNaO₃

Cor e Forma: Solid

Peso molecular: 339.32

Ref: TM-T86778