CAS 1421063-89-9

Fórmula: C33H36F3N3O

InChI: InChI=1S/C33H36F3N3O/c34-33(35,36)28-17-26-21-39(15-11-30(26)37-20-28)31(40)32-12-3-6-27(32)18-29(19-32)38-13-9-23(10-14-38)25-8-7-22-4-1-2-5-24(22)16-25/h1-2,4-5,7-8,16-17,20,23,27,29H,3,6,9-15,18-19,21H2/t27-,29?,32-/m1/s1

Chave InChI: JGOUOMQAEWOSMK-VPQXSCEVSA-N

SMILES: C1C[C@@H]2CC(C[C@@]2(C1)C(=O)N3CCC4=C(C3)C=C(C=N4)C(F)(F)F)N5CCC(CC5)C6=CC7=CC=CC=C7C=C6

CCR2 antagonist 6

CAS: 1421063-89-9

CCR2 antagonist6 (Example 98) is a CCR2 antagonist with a Kb value of 0.215 μM for CCR2 and 0.174 μM for hCCR2B. It is utilized in research pertaining to inflammation and autoimmune diseases.

Fórmula: C₃₃H₃₆F₃N₃O

Peso molecular: 547.65

Ref: TM-T218744