CAS 1421693-22-2

Fórmula: C15H15FN6O2S2

InChI: InChI=1S/C15H15FN6O2S2/c1-8-13(25-15(18-2)20-8)12-11(16)7-19-14(22-12)21-9-4-3-5-10(6-9)26(17,23)24/h3-7H,1-2H3,(H,18,20)(H2,17,23,24)(H,19,21,22)

Chave InChI: GAIOPWBQKZMUNO-UHFFFAOYSA-N

SMILES: CC1=C(SC(=N1)NC)C2=NC(=NC=C2F)NC3=CC(=CC=C3)S(=O)(=O)N

CDKI-73

CAS: 1421693-22-2

CDKI-73: strong CDK9 blocker, Ki 4 nM, kills CLL cells selectively, aids cisplatin.

Fórmula: C₁₅H₁₅FN₆O₂S₂

Pureza: 98.11%

Cor e Forma: Solid

Peso molecular: 394.447

Ref: TM-T14919

CDKI-73

CAS: 1421693-22-2

CDKI-73

Fórmula: C₁₅H₁₅FN₆O₂S₂

Pureza: ≥95%

Peso molecular: 394.45

Ref: 54-BUP04200

CDKI-73

CAS: 1421693-22-2

Fórmula: C₁₅H₁₅FN₆O₂S₂

Pureza: 98%

Peso molecular: 394.4470

Ref: IN-DA009CHF

Asnuciclib

CAS: 1421693-22-2

3-((5-Fluoro-4-(4-methyl-2-(methylamino)thiazol-5-yl)pyrimidin-2-yl)amino)benzenesulfonamide

Fórmula: C₁₅H₁₅FN₆O₂S₂

Pureza: 98%

Peso molecular: 394.45

Ref: IN-DG630260

CDKI-73

CAS: 1421693-22-2

CDKI-73 is a selective cyclin-dependent kinase (CDK) inhibitor, which originates from targeted medicinal chemistry efforts aimed at modulating cell cycle progression. This compound operates through the inhibition of specific CDK enzymes, crucial regulators of the cell cycle, and transcriptional processes. By selectively targeting these kinases, CDKI-73 disrupts the phosphorylation events necessary for cell cycle progression, thereby inducing cell cycle arrest and promoting apoptosis in cancer cells.

Fórmula: C₁₅H₁₅FN₆O₂S₂

Pureza: Min. 95%

Peso molecular: 394.45 g/mol

Ref: 3D-WGC69322