CAS 1430213-30-1

Fórmula: C15H9F4N5OS

InChI: InChI=1S/C15H9F4N5OS/c16-11-2-1-9(7-10(11)15(17,18)19)21-13(25)22-14-24-23-12(26-14)8-3-5-20-6-4-8/h1-7H,(H2,21,22,24,25)

Chave InChI: WMCOYUSJXXCHFH-UHFFFAOYSA-N

SMILES: C1=CC(=C(C=C1NC(=O)NC2=NN=C(S2)C3=CC=NC=C3)C(F)(F)F)F

ML216

CAS: 1430213-30-1

ML216

Fórmula: C₁₅H₉F₄N₅OS

Pureza: ≥95%

Peso molecular: 383.32

Ref: 54-BUP06162

1-(4-Fluoro-3-(Trifluoromethyl)Phenyl)-3-(5-(Pyridin-4-Yl)-1,3,4-Thiadiazol-2-Yl)Urea

CAS: 1430213-30-1

1-(4-Fluoro-3-(Trifluoromethyl)Phenyl)-3-(5-(Pyridin-4-Yl)-1,3,4-Thiadiazol-2-Yl)Urea

Fórmula: C₁₅H₉F₄N₅OS

Pureza: 98+%

Peso molecular: 383.32

Ref: 54-PC108707

ML216

CAS: 1430213-30-1

Fórmula: C₁₅H₉F₄N₅OS

Pureza: %

Cor e Forma: Solid

Peso molecular: 383.3235

Ref: IN-DA009CDG

ML216

CAS: 1430213-30-1

ML216 (CID-49852229) inhibits BLM helicase (IC50: 1.8 μM), 28-fold selective over RECQ1, RECQ5, and UvrD (IC50s > 50 μM).

Fórmula: C₁₅H₉F₄N₅OS

Pureza: 98.12%

Cor e Forma: Yellow Solid

Peso molecular: 383.323

Ref: TM-T5413

ML216

CAS: 1430213-30-1

1-(4-Fluoro-3-(trifluoromethyl)phenyl)-3-(5-(pyridin-4-yl)-1,3,4-thiadiazol-2-yl)urea

Fórmula: C₁₅H₉F₄N₅OS

Pureza: 98+%

Peso molecular: 383.32

Ref: IN-DG630270

1-(4-Fluoro-3-(trifluoromethyl)phenyl)-3-(5-(pyridin-4-yl)-1,3,4-thiadiazol-2-yl)urea

CAS: 1430213-30-1

Pureza: 98+%

Peso molecular: 383.3200073

Ref: 10-F870102

ML-216

Produto Controlado

CAS: 1430213-30-1

Applications ML-216 is a small molecule inhibitor of Bloom (BLM) helicase.
References Rosenthal, A., et al.: Bioorg. Med. Chem. Lett., 23, 5660 (2013); Nguyen, G., et al.: Chem. Biol., 20, 55(2013)

Fórmula: C₁₅H₉F₄N₅OS

Cor e Forma: Neat

Peso molecular: 383.324

Ref: TR-M425095

ML216

CAS: 1430213-30-1

ML216 is a chemotherapeutic drug that inhibits the repair mechanism of prostate cancer cells. It binds to leukocyte antigen (LFA-1) on the surface of tumor cells, and blocks the activity of suppressor genes that regulate the growth and development of these cells. ML216 has been shown to be active against prostate cancer cell lines in vitro and in vivo studies. This drug also has membrane permeability and anticancer activity.

Fórmula: C₁₅H₉F₄N₅OS

Pureza: Min. 95%

Peso molecular: 383.32 g/mol

Ref: 3D-FHC21330