CAS 1432630-26-6

Fórmula: C23H34N5O14P

InChI: InChI=1S/C19H30N5O10P.C4H4O4/c1-12(2)33-18(25)28-9-31-35(27,32-10-29-19(26)34-13(3)4)11-30-14(5)6-24-8-23-15-16(20)21-7-22-17(15)24;5-3(6)1-2-4(7)8/h7-8,12-14H,6,9-11H2,1-5H3,(H2,20,21,22);1-2H,(H,5,6)(H,7,8)/b;2-1+/t14-;/m0./s1

Chave InChI: VCMJCVGFSROFHV-KZHAMYRLSA-N

SMILES: C[C@@H](CN1C=NC2=C(N=CN=C21)N)OCP(=O)(OCOC(=O)OC(C)C)OCOC(=O)OC(C)C.C(=C/C(=O)O)\C(=O)O

Tenofovir Disoproxil Related Compound A

CAS: 1432630-26-6

Compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure, nesoi

Fórmula: C₁₉H₃₀N₅O₁₀P·C₄H₄O₄

Cor e Forma: White Off-White Powder

Peso molecular: 519.17303

Ref: 45-1643612

Tenofovir Disoproxil USP Related Compound A ((S)-Tenofovir Disoproxil Fumarate)

CAS: 1432630-26-6

Fórmula: C₁₉H₃₀N₅O₁₀P·C₄H₄O₄

Cor e Forma: White To Off-White Solid

Peso molecular: 519.45 116.07

Ref: 4Z-T-0214

Tenofovir impurity 2 fumarate

CAS: 1432630-26-6

Tenofovir impurity 2 fumarate ((S)-Tenofovir disoproxil fumarate) is an impurity of Tenofovir fumarate.

Fórmula: C₂₃H₃₄N₅O₁₄P

Peso molecular: 635.51

Ref: TM-TYD-06977

(S)-Tenofovir Disoproxil Fumarate

CAS: 1432630-26-6

Cor e Forma: Neat

Ref: 86-MM1329.15

(S)-Tenofovir Disoproxil Fumarate

Produto Controlado

CAS: 1432630-26-6

Impurity Tenofovir Disoproxil USP Related Compound A
Applications The S-enantiomeric impurity of the antiviral Tenofovir Disoproxil Fumarate (T018505(P)), which is an acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor and used as an anti-HIV agent.Tenofovir Disoproxil USP Related Compound A.
References Shaw, J. P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007)

Fórmula: C₁₉H₃₀N₅O₁₀P·C₄H₄O₄

Cor e Forma: Neat

Peso molecular: 635.52

Ref: TR-T018506

Tenofovir Disoproxil USP Related Compound A

CAS: 1432630-26-6

Fórmula: C₁₉H₃₀N₅O₁₀PC₄H₄O₄

Peso molecular: 519.4 : 116.1

Ref: ST-EA-CP-T5029

(S)-Tenofovir disoproxil fumarate

CAS: 1432630-26-6

Tenofovir disoproxil fumarate is a prodrug of tenofovir that is used as a clinical medication to treat HIV. Tenofovir works by inhibiting reverse transcriptase, an enzyme required for the production of viral DNA. The flow rate of this drug is high and it has a sensitivity of less than 1 ng/mL. Tenofovir disoproxil fumarate contains impurities such as methoxy, which can affect the chiral purity and sensitivity of the drug. It also contains tenofovir, which is used as an intermediate in its synthesis. This drug can be detected using chromatographic methods, which use n-hexane and a wavelength below 220 nm for liquid chromatography analysis.

Fórmula: C₂₃H₃₄N₅O₁₄P

Pureza: Min. 95%

Peso molecular: 635.5 g/mol

Ref: 3D-HHC63026