CAS 1437321-24-8

Fórmula: C31H26F2N4O6

InChI: InChI=1S/C31H26F2N4O6/c1-17(2)36-16-22(30(39)37(31(36)40)20-8-5-18(32)6-9-20)29(38)35-19-7-10-26(23(33)13-19)43-25-11-12-34-24-15-28(42-4)27(41-3)14-21(24)25/h5-17H,1-4H3,(H,35,38)

Chave InChI: FKCWHHYUMFGOPY-UHFFFAOYSA-N

SMILES: CC(C)N1C=C(C(=O)N(C1=O)C2=CC=C(C=C2)F)C(=O)NC3=CC(=C(C=C3)OC4=C5C=C(C(=CC5=NC=C4)OC)OC)F

5-Pyrimidinecarboxamide, N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]-3-fluorophenyl]-3-(4-fluorophenyl)-1,2,3,4-tetrahydro-1-(1-methylethyl)-2,4-dioxo-

CAS: 1437321-24-8

Fórmula: C₃₁H₂₆F₂N₄O₆

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 588.5581

Ref: IN-DA001IAD

CEP-40783

CAS: 1437321-24-8

CEP-40783

Fórmula: C₃₁H₂₆F₂N₄O₆

Pureza: ≥98%

Peso molecular: 588.56

Ref: 54-BUP10137

CEP-40783

CAS: 1437321-24-8

CEP-40783 (RXDX-106) is an effective, specific and orally active AXL/c-Met inhibitor (IC50: 7/12 nM). It also inhibits MER and TYRO3 (IC50: 29/19 nM).

Fórmula: C₃₁H₂₆F₂N₄O₆

Pureza: 99.76% - 99.84%

Cor e Forma: White Solid

Peso molecular: 588.56

Ref: TM-T4426

CEP-40783

CAS: 1437321-24-8

N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)-3-fluorophenyl)-3-(4-fluorophenyl)-1-isopropyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide

Fórmula: C₃₁H₂₆F₂N₄O₆

Pureza: 98%

Peso molecular: 588.56

Ref: IN-DG00775180

5-Pyrimidinecarboxamide, N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]-3-fluorophenyl]-3-(4-fluorophenyl)-1,2,3,4-tetrahydro-1-(1-methylethyl)-2,4-dioxo-

CAS: 1437321-24-8

Pureza: 98%

Peso molecular: 588.5679932

Ref: 10-F861895

CEP-40783

CAS: 1437321-24-8

CEP-40783 is a potent, selective and orally bioavailable epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor. CEP-40783 inhibits EGFR autophosphorylation and downstream signaling pathways in wild-type mice, as well as tumor cells of different origins. It has been shown to inhibit the growth of cancer cells by inducing apoptosis and inhibiting cell proliferation. CEP-40783 also has an immunosuppressive effect on T cells, which may be beneficial for autoimmune diseases.

Fórmula: C₃₁H₂₆F₂N₄O₆

Pureza: Min. 95%

Peso molecular: 588.56 g/mol

Ref: 3D-MHC32124