CAS 144143-96-4

Ácido 2-tiofenopropanoico, α-[[2-butil-1-[(4-carboxifenil)metil]-1H-imidazol-5-il]metileno]-, (αE)-, metanossulfonato (1:1)

Descrição:

Ácido 2-tiofenopropanoico, α-[[2-butil-1-[(4-carboxifenil)metil]-1H-imidazol-5-il]metileno]-, (αE)-, metanossulfonato (1:1) é um composto orgânico complexo caracterizado por suas características estruturais únicas, incluindo um anel de tiofeno e uma parte de imidazol. Este composto exibe propriedades ácidas e básicas devido à presença de funções de ácido carboxílico e imidazol, que podem participar de várias reações químicas, incluindo transferência de prótons e coordenação com íons metálicos. O grupo metanosulfonato aumenta sua solubilidade em solventes polares, tornando-o adequado para várias aplicações em síntese orgânica e química medicinal. Além disso, a presença dos grupos butila e fenila contribui para suas características hidrofóbicas, influenciando sua atividade biológica e interação com alvos celulares. A estereoquímica do composto, indicada pela designação (αE), sugere arranjos espaciais específicos que podem afetar sua reatividade e propriedades de ligação. No geral, esta substância é de interesse na pesquisa farmacêutica, particularmente por suas potenciais aplicações terapêuticas.

Fórmula: C₂₃H₂₄N₂O₄S·CH₄O₃S

InChI: InChI=1S/C23H24N2O4S.CH4O3S/c1-2-3-6-21-24-14-19(12-18(23(28)29)13-20-5-4-11-30-20)25(21)15-16-7-9-17(10-8-16)22(26)27;1-5(2,3)4/h4-5,7-12,14H,2-3,6,13,15H2,1H3,(H,26,27)(H,28,29);1H3,(H,2,3,4)/b18-12+;

Chave InChI: InChIKey=DJSLTDBPKHORNY-XMMWENQYSA-N

SMILES: C(N1C(/C=C(\CC2=CC=CS2)/C(O)=O)=CN=C1CCCC)C3=CC=C(C(O)=O)C=C3.S(C)(=O)(=O)O

Sinónimos:

• 2-Thiophenepropanoic acid, α-[[2-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-yl]methylene]-, (E)-, monomethanesulfonate
• 2-Thiophenepropanoic acid, α-[[2-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-yl]methylene]-, (αE)-, methanesulfonate (1:1)
• 2-Thiophenepropanoic acid, α-[[2-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-yl]methylene]-, (αE)-, monomethanesulfonate
• 4-({2-butyl-5-[(1E)-2-carboxy-3-thiophen-2-ylprop-1-en-1-yl]-1H-imidazol-1-yl}methyl)benzoic acid methanesulfonate
• 4-[[2-Butyl-5-(2-Carboxy-3-Thiophen-2-Yl-Prop-1-Enyl)-Imidazol-1-Yl]Methyl]Benzoic Acid Mesylate
• Eprosartan Methanesulfonate
• Skf 108566J
• Eprosartan mesylate

Eprosartan Mesylate ((E)-2-Butyl-1-(p-carboxybenzyl)-α-2-thenylimidazole-5-acrylic acid, monomethanesulfonate)

CAS: 144143-96-4

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Fórmula: C₂₃H₂₄N₂O₄S·CH₄O₃S

Cor e Forma: White Crystalline Powder

Peso molecular: 424.14568

Ref: 45-1238217

Eprosartan Mesylate

CAS: 144143-96-4

Eprosartan Mesylate

Fórmula: C₂₄H₂₈N₂O₇S₂

Pureza: 99%

Peso molecular: 520.62

Ref: 54-OR1028758

4-({2-butyl-5-[(1E)-2-carboxy-2-(thiophen-2-ylmethyl)eth-1-en-1-yl]-1H-imidazol-1-yl}methyl)benzoic acid; methanesulfonic acid

CAS: 144143-96-4

Fórmula: C₂₄H₂₈N₂O₇S₂

Pureza: 99%

Cor e Forma: Solid

Peso molecular: 520.6183

Ref: IN-DA001IZZ

Eprosartan Mesylate

CAS: 144143-96-4

Eprosartan Mesylate

Fórmula: C₂₃H₂₄N₂O₄S·CH₄O₃S

Pureza: ≥98%

Peso molecular: 520.62

Ref: 54-BUP15659

Eprosartan Mesylate

CAS: 144143-96-4

Fórmula: C₂₃H₂₄N₂O₄S·CH₄O₃S

Cor e Forma: White To Off-White Solid

Peso molecular: 424.52 96.11

Ref: 4Z-E-151

Eprosartan mesylate

CAS: 144143-96-4

Fórmula: C₂₃H₂₄N₂O₄S·CH₄O₃S

Peso molecular: 520.62

Ref: 7W-GP8368

Eprosartan Mesylate

CAS: 133040-01-4, 144143-96-4

Fórmula: C₂₃H₂₄N₂O₄S·CH₄O₃S

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 520.62

Ref: 3B-E1161

Eprosartan mesylate

Produto Controlado

CAS: 144143-96-4

Fórmula: C₂₃H₂₄N₂O₄S·CH₄O₃S

Cor e Forma: Neat

Peso molecular: 520.62

Ref: 04-C13188000

Eprosartan Mesilate

Produto Controlado

CAS: 144143-96-4

Fórmula: C₂₃H₂₄N₂O₄S·CH₄O₃S

Cor e Forma: Off-White

Peso molecular: 520.62

Ref: 86-MM1577.00

Eprosartan Mesylate

CAS: 144143-96-4

Eprosartan Mesylate (SKF-108566J) is a competitive and reversible Angiotensin II Receptor Blocker.

Fórmula: C₂₃H₂₄N₂O₄S·CH₄O₃S

Pureza: 99.72% - 99.93%

Cor e Forma: A White To Off- White Powder

Peso molecular: 520.62

Ref: TM-T2531

Eprosartan Mesylate

Produto Controlado

CAS: 144143-96-4

Applications Eprosartan Mesylate is an angiotensin II receptor antagonists. Eprosartan Mesylate is used as an antihypertensive agent.
References Sheng, J. et al.: J. Pharmac. Sci., 88., 1021 (1999); Punzi, H.A. et al.: J. Hum. Hypertens., 18, 655 (2004);

Fórmula: C₂₃H₂₄N₂O₄S·CH₄O₃S

Cor e Forma: Neat

Peso molecular: 520.62

Ref: TR-E590105

Eprosartan mesylate

CAS: 144143-96-4

Eprosartan mesylate is an angiotensin II receptor antagonist and a prodrug of eprosartan. It is used in the treatment of hypertension, congestive heart failure, and for the prophylaxis of organ rejection in renal transplantation. This drug has been shown to inhibit the activation of nuclear factor-κB (NF-κB) and the production of inflammatory cytokines such as growth factor-β1 (GF-β1). Eprosartan mesylate has also been shown to have a beneficial effect on experimental models of type 2 diabetes and metabolic disorders. In clinical trials, it was found that losartan had similar effects on lowering blood pressure as eprosartan mesylate, but the combination increased blood pressure more than either agent alone. Eprosartan mesylate should not be taken with drugs that are metabolized by cytochrome P450 enzymes because they may lead to serious adverse effects such

Fórmula: C₂₃H₂₄N₂O₄S•CH₄O₃S

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 520.62 g/mol

Ref: 3D-FE61516

Eprosartan mesylate

CAS: 144143-96-4

(E)-4-((2-Butyl-5-(2-carboxy-3-(thiophen-2-yl)prop-1-en-1-yl)-1H-imidazol-1-yl)methyl)benzoic acid methanesulfonic acid salt

Fórmula: C₂₄H₂₈N₂O₇S₂

Pureza: 99%

Peso molecular: 520.62

Ref: IN-DG127397

Eprosartan Mesylate

CAS: 144143-96-4

Fórmula: C₂₃H₂₄N₂O₄SCH₄O₃S

Peso molecular: 424.52 : 96.1

Ref: ST-EA-CP-E64008