CAS 1447-88-7

Hispidulina

Descrição:

Hispidulina é um composto flavonoide que ocorre naturalmente, classificado na categoria de flavonas. É derivado principalmente de várias fontes vegetais, particularmente aquelas da família Asteraceae. A estrutura química de Hispidulina apresenta uma espinha dorsal de cromona, que é característica dos flavonoides, e inclui grupos hidroxila que contribuem para sua atividade biológica. Este composto é conhecido por suas potenciais propriedades antioxidantes, anti-inflamatórias e neuroprotetoras, tornando-o de interesse na pesquisa farmacológica. Além disso, Hispidulina tem sido estudado por seus efeitos em várias vias celulares, sugerindo aplicações terapêuticas potenciais em condições como câncer e doenças neurodegenerativas. Sua solubilidade e estabilidade podem variar dependendo do solvente e das condições ambientais, o que é importante para sua aplicação tanto em pesquisa quanto em uso medicinal potencial. No geral, Hispidulina representa uma área significativa de estudo dentro da química de produtos naturais, com pesquisas em andamento destinadas a elucidar seus mecanismos de ação e potenciais benefícios à saúde.

Fórmula: C₁₆H₁₂O₆

InChI: InChI=1/C16H12O6/c1-21-16-11(19)7-13-14(15(16)20)10(18)6-12(22-13)8-2-4-9(17)5-3-8/h2-7,17,19-20H,1H3

Chave InChI: InChIKey=IHFBPDAQLQOCBX-UHFFFAOYSA-N

SMILES: OC1=C2C(OC(=CC2=O)C3=CC=C(O)C=C3)=CC(O)=C1OC

Sinónimos:

• 4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-
• 4′,5,7-Trihydroxy-6-methoxyflavone
• 5,7,4′-Trihydroxy-6-methoxyflavone
• 5,7-Dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one
• 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one
• 6-Methoxy-5,7,4′-trihydroxyflavone
• 6-Methoxyapigenin
• 6-Methylscutellarein
• 6-O-Methylscutellarein
• Dinatin
• Flavone, 4′,5,7-trihydroxy-6-methoxy-
• Hispedulin
• Hispiludin
• NSC 122415
• Salvitin
• Scutellarein 6-Methyl Ether
• Hispidulin
• Hispidulin, >99%
• 1447-88-7
• Hispidulin(Dinatin)
• 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxychromen-4-one
• 4',5,7-Trihydroxy-6-methoxyflavone

Hispidulin

CAS: 1447-88-7

Hispidulin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Fórmula: C₁₆H₁₂O₆

Pureza: (HPLC) ≥95%

Cor e Forma: Powder

Peso molecular: 300.27

Ref: 11-1451

4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-

CAS: 1447-88-7

Fórmula: C₁₆H₁₂O₆

Pureza: 99%

Cor e Forma: Solid

Peso molecular: 300.2629

Ref: IN-DA001K12

Hispidulin

CAS: 1447-88-7

Hispidulin

Fórmula: C₁₆H₁₂O₆

Pureza: ≥95%

Peso molecular: 300.26

Ref: 54-BUP17580

Hispidulin

CAS: 1447-88-7

Fórmula: C₁₆H₁₂O₆

Peso molecular: 300.27

Ref: 7W-GY8195

Hispidulin (Standard)

CAS: 1447-88-7

Hispidulin (Standard) is a reference standard for research and analysis in studies involving Hispidulin. Hispidulin, a natural flavone with a broad spectrum of biological activities, is a Pim-1 inhibitor (IC50: 2.71 μM).

Fórmula: C₁₆H₁₂O₆

Cor e Forma: Solid

Peso molecular: 300.26

Ref: TM-TMSM-1652

Hispidulin

CAS: 1447-88-7

Hispidulin has anti-oxidative, anti-inflammatory, anti-cancer, antiepileptic, neuroprotective, anti-osteoporotic and bone resorption attenuating effects, it targets the VEGF receptor 2-mediated PI3K/Akt/mTOR signaling pathway in endothelial cells, leading to the suppression of pancreatic tumor growth and angiogenesis. Hispidulin can ameliorate high glucose-mediated endothelial dysfunction via inhibiting PKCβII-associated NLRP3 inflammasome activation and NF-κB signaling, it has potential application in the prevention and treatment of diabetic vascular complications. Hispidulin can inhibit platelet aggregation by elevating cAMP levels by a mechanism different from that of theophylline or PGE1.

Fórmula: C₁₆H₁₂O₆

Pureza: 95%~99%

Peso molecular: 300.266

Ref: BP-BP0730

Hispidulin

CAS: 1447-88-7

Hispidulin, a natural flavone with a broad spectrum of biological activities, is a Pim-1 inhibitor (IC50: 2.71 μM).

Fórmula: C₁₆H₁₂O₆

Pureza: 98.53% - 99.87%

Cor e Forma: Solid

Peso molecular: 300.26

Ref: TM-TQ0201

Hispidulin

CAS: 1447-88-7

Fórmula: C₁₆H₁₂O₆

Peso molecular: 300.27

Ref: 4Z-H-031001

Hispidulin

CAS: 1447-88-7

Oxygen-heterocyclic compound

Fórmula: C₁₆H₁₂O₆

Pureza: ≥ 95.0 % (HPLC)

Cor e Forma: Powder

Peso molecular: 300.27

Ref: 5G-83335

Hispidulin

Produto Controlado

CAS: 1447-88-7

Applications Hispidulin is a potent benzodiazepine (BZD) receptor ligand.

Fórmula: C₁₆H₁₂O₆

Cor e Forma: Neat

Peso molecular: 300.27

Ref: TR-H456340

Hispidulin

CAS: 1447-88-7

Hispidulin is a naturally occurring flavonoid compound, which is predominantly derived from plants such as Salvia and Artemisia species. This bioactive compound exhibits a broad spectrum of pharmacological activities that have garnered attention in the scientific community. Its mode of action involves the modulation of cellular pathways, including the inhibition of enzymes like cyclooxygenases, which are pivotal in inflammatory responses. Furthermore, Hispidulin has been shown to influence neurotransmitter systems, including GABAergic activity, indicating potential neuroprotective effects.

Fórmula: C₁₆H₁₂O₆

Pureza: Min. 98 Area-%

Cor e Forma: Off-White Powder

Peso molecular: 300.26 g/mol

Ref: 3D-FH73251

Hispidulin - Bio-X ™

CAS: 1447-88-7

This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Fórmula: C₁₆H₁₂O₆

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 300.26 g/mol

Ref: 3D-BH300089

Hispidulin

CAS: 1447-88-7

5,7-Dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one

Fórmula: C₁₆H₁₂O₆

Pureza: 99%

Peso molecular: 300.26

Ref: IN-DG39407

Hispidulin

CAS: 1447-88-7

Pureza: 99%

Peso molecular: 300.2659912

Ref: 10-F814360