CAS 144701-48-4
:Telmisartana
Descrição:
Telmisartana é um antagonista do receptor de angiotensina II utilizado principalmente no tratamento da hipertensão e para reduzir o risco cardiovascular. É caracterizado pela sua capacidade de bloquear seletivamente o receptor AT1, que desempenha um papel crucial na regulação da pressão arterial e do equilíbrio de fluidos. Telmisartana é um pó cristalino branco a quase branco que é praticamente insolúvel em água, mas solúvel em solventes orgânicos como etanol e metanol. Sua fórmula molecular é C33H30N4O2, e tem um peso molecular relativamente alto. A substância apresenta uma longa meia-vida, permitindo a dosagem uma vez ao dia, o que melhora a adesão do paciente. Telmisartana também possui propriedades adicionais, como benefícios potenciais na síndrome metabólica e efeitos protetores na função renal. É importante notar que, assim como outros medicamentos, Telmisartana pode ter efeitos colaterais, incluindo tontura, fadiga e distúrbios gastrointestinais. No geral, Telmisartana é um medicamento bem estabelecido no manejo da hipertensão, com um perfil de segurança favorável e eficácia na redução do risco cardiovascular.
Fórmula:C16H18N4O3S
InChI:InChI=1/C33H30N4O2/c1-7-12-33-39-34-24(2)21-27(35-38-30-15-10-11-16-31(30)40(35)6)22-32(34)41(33)23-25-17-19-26(20-18-25)28-13-8-9-14-29(28)36(42)43-37(3,4)5/h8-11,13-22H,7,12,23H2,1-6H3
Chave InChI:InChIKey=RMMXLENWKUUMAY-UHFFFAOYSA-N
SMILES:C(N1C=2C(N=C1CCC)=C(C)C=C(C2)C=3N(C)C=4C(N3)=CC=CC4)C5=CC=C(C=C5)C6=C(C(O)=O)C=CC=C6
Sinónimos:- 2-(4-[[4-Methyl-6-(1-methyl-1H-1,3-benzodiazol-2-yl)-2-propyl-1H-1,3-benzodiazol-1-yl]methyl]phenyl)benzoic acid
- 2-[4-[[4-Methyl-6-(1-Methylbenzoimidazol-2-Yl)-2-Propyl-Benzoimidazol-1-Yl]Methyl]Phenyl]Benzoic Acid
- 2-[4-[[4-Methyl-6-(1-methylbenzimidazol-2-yl)-2-propylbenzimidazol-1-yl]methyl]phenyl]benzoic acid
- 4'-[(1,7'-dimethyl-2'-propyl-1H,3'H-2,5'-bibenzimidazol-3'-yl)methyl]biphenyl-2-carboxylic acid
- 4'-[[4-Methyl-6-(1-methyl-2-benzimidazolyl)-2-propyl-1-benzimidazolyl]methyl]-2-biphenylcarboxylic acid
- 4'[(1,4'-Dimethyl-2'-propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl][1,1'-biphenyl]-2-carboxylic acid
- Bibr 277
- Bibr 277Se
- Kinzalmono
- Micardis
- Pritor
- Semintra
- Telday
- Telmisartar
- Telsar
- Telsite
- Tolura
- [1,1'-Biphenyl]-2-carboxylic acid, 4'-[(1,4'-dimethyl-2'-propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl]-
- [1,1'-Biphenyl]-2-carboxylic acid, 4'-[(1,7'-dimethyl-2'-propyl[2,5'-bi-1H-benzimidazol]-3'-yl)methyl]-
- [1,1'-Biphenyl]-2-carboxylicacid,4'-[(1,4'-dimethyl-2'-propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl]
- tert-butyl 4'-[(1,7'-dimethyl-2'-propyl-1H,3'H-2,5'-bibenzimidazol-3'-yl)methyl]biphenyl-2-carboxylate
- Telmisartan
- 4'-(1,7'-Dimethyl-2'-propyl-1H-
- Telmisartan99.5%
- Telmisartan (150 mg)
- TelmisartanC33H30N402
- TelMisartan API
- TelMisartan (Micardis)
- TU-199
- 4-chloromethyl-5-methyl-1,3-dioxol-2-tone
- Telmisaran
- RITOR
- 4'-[[1,4'-Dimethyl-2
- TIMETAZIDINE
- TIMISHATAN
- Ver mais sinónimos
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Telmisartan
CAS:Fórmula:C33H30N4O2Pureza:>98.0%(T)(HPLC)Cor e Forma:White to Almost white powder to crystalPeso molecular:514.63Telmisartan
CAS:TelmisartanFórmula:C33H30N4O2Pureza:99.4%Cor e Forma:White. To. Off-WhitePeso molecular:514.23688TELMISARTAN FOR SYSTEM SUITABILITY CRS
CAS:TELMISARTAN FOR SYSTEM SUITABILITY CRSFórmula:C33H30N4O2Cor e Forma:PowderPeso molecular:514.6169TELMISARTAN FOR PEAK IDENTIFICATION CRS
CAS:TELMISARTAN FOR PEAK IDENTIFICATION CRSFórmula:C33H30N4O2Cor e Forma:PowderPeso molecular:514.6169Telmisartan
CAS:Cardiovascular drugs, nesoiFórmula:C33H30N4O2Cor e Forma:White Pale Yellow PowderPeso molecular:514.236884'-[(1,4'-Dimethyl-2'-propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl][1,1'-biphenyl]-2-carboxylic acid
CAS:Fórmula:C33H30N4O2Pureza:98%Cor e Forma:SolidPeso molecular:514.6169Telmisartan
CAS:Telmisartan (BIBR 277) is an Angiotensin 2 Receptor Blocker. The mechanism of action of telmisartan is as an Angiotensin 2 Receptor Antagonist.Fórmula:C33H30N4O2Pureza:99.88% - 99.97%Cor e Forma:White Or Off White Crystalline PowderPeso molecular:514.62Telmisartan
CAS:Fórmula:C33H30N4O2Pureza:99.0 - 101.0 % (dried basis)Cor e Forma:White, off-white or very pale yellow crystalline powderPeso molecular:514.62Telmisartan-d4 (benzyl-2,3,5,6-d4)
CAS:Pureza:99 atom % DCor e Forma:White To Off White SolidPeso molecular:518.65Telmisartan
CAS:Produto ControladoStability Hygroscopic
Applications Telmisartan is an angiotensin II receptor antagonist.
References Wienen, W., et al.: Brit. J. Pharmacol., 110, 245 (1993), Neutel, J.M., and Smith, D.H.G.: Adv. Ther., 15, 206 (1998)Fórmula:C33H30N4O2Cor e Forma:NeatPeso molecular:514.62Telmisartan
CAS:Telmisartan is a drug that belongs to the angiotensin II receptor antagonist class. Telmisartan is used to treat high blood pressure and heart failure. It blocks the action of angiotensin II, which prevents the constriction of blood vessels and lowers blood pressure. Telmisartan has been shown to reduce atherosclerotic lesion size in two-way crossover studies in rats with hypertension induced by high salt intake. Telmisartan also has antihypertensive and cardioprotective effects as well as dna binding activity, which may be important for its therapeutic effect on cardiovascular disorders. Telmisartan has not been found to have significant drug interactions with other medications and does not affect the metabolism of other drugs in the body. This drug should not be taken together with certain medications such as antifungal agents, erythromycin, or clarithromycin due to an increased risk of serious adverse effects on the kidneys or liver.Fórmula:C33H30N4O2Pureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:514.62 g/molTelmisartan - Bio-X ™
CAS:Telmisartan is a drug that belongs to the angiotensin II receptor antagonist class. It acts by blocking the binding of angiotensin II to its receptors, thereby inhibiting the activation of angiotensin-converting enzyme, thus causing the blood vessels to relax. Telmisartan has been shown to reduce blood pressure and improve lipid profiles in patients with hypertension and hyperlipidaemia. Furthermore, this drug has anti-inflammatory properties and with research may be useful in treating infectious diseases.
Fórmula:C33H30N4O2Pureza:Min. 95%Cor e Forma:PowderPeso molecular:514.62 g/mol
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