CAS 145100-51-2

N-(5-cloro-2-piridil)bis(trifluorometanossulfonimida)

Descrição:

N-(5-cloro-2-piridil)bis(trifluorometanosulfonamida), com o número CAS 145100-51-2, é um composto químico caracterizado por sua estrutura única, que inclui um anel de piridina substituído por um átomo de cloro e dois grupos trifluorometanosulfonamida. Este composto é tipicamente um sólido à temperatura ambiente e é conhecido por sua alta estabilidade térmica e solubilidade em solventes orgânicos polares. A presença de grupos trifluorometanosulfonamida confere uma forte acidez e o torna um potente eletrófilo, que pode ser utilizado em várias reações químicas, incluindo substituições nucleofílicas e como reagente em síntese orgânica. Além disso, o substituinte de cloro no anel de piridina pode influenciar a reatividade do composto e sua interação com outras espécies químicas. Devido às suas propriedades, este composto pode encontrar aplicações em farmacêuticos, agroquímicos e ciência dos materiais, particularmente no desenvolvimento de líquidos iônicos e como catalisador em transformações orgânicas. Precauções de segurança devem ser observadas ao manusear este composto, pois pode representar riscos à saúde.

Fórmula: C₇H₃ClF₆N₂O₄S₂

InChI: InChI=1S/C7H3ClF6N2O4S2/c8-4-1-2-5(15-3-4)16(21(17,18)6(9,10)11)22(19,20)7(12,13)14/h1-3H

Chave InChI: InChIKey=TUFGVZMNGTYAQD-UHFFFAOYSA-N

SMILES: N(S(C(F)(F)F)(=O)=O)(S(C(F)(F)F)(=O)=O)C1=CC=C(Cl)C=N1

Sinónimos:

• 1-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine
• 2-[N,N-Bis(Trifluoromethanesulfonyl)Amino]-5-Chloropyridine
• 2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine
• 2-[N,N-Bis(trifluoromethanesulphonyl)amino]-5-chloropyridine
• 2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine
• Bistrifluoromethylsulfonylaminochloropyridine
• Comins
• Comins' reagent
• Methanesulfonamide, N-(5-chloro-2-pyridinyl)-1,1,1-trifluoro-N-[(trifluoromethyl)sulfonyl]-
• N,N-Bis(trifluoromethylsulfonyl)-5-chloro-2-pyridinamine
• N,N-Bis(trifluoromethylsulfonyl)-5-chloro-2-pyridylamine
• N-(5-Chloro-2-pyridinyl)-1,1,1-trifluoro-N-[(trifluoromethyl)sulfonyl]methanesulfonamide
• N-(5-Chloro-2-pyridyl)-N-(trifluoromethanesulfonyl)trifluoromethanesulfonamide
• N-(5-Chloro-2-pyridyl)bis(trifluoromethanesulfonimide)
• N-(5-Chloro-2-pyridyl)triflimide
• N-(5-chloropyridin-2-yl)-1,1,1-trifluoro-N-[(trifluoromethyl)sulfonyl]methanesulfonamide
• NSC 683533
• N-(5-CHLORO-2-PYRIDYL)BIS(TRILFUOROMETHANESULFONIMIDE)
• 2-[N,N-bis(trifluoromethylsulphony)amino]-5-chloropyridine
• n-(5-chloro-2-pyridyl)bis(trifluoromethanesulfonyl)imide
• 2-N,N-Bis(trifluoromethanesulfonyl)aminoü-5-chloropyridine, 99%
• N-(5-chloro-2-pyridyl)bis(trifluromethanesulfonimide
• 2-[N,N-Bis(trifluoromethanesulfonyl)amino]-5-chloropyridine [Triflating Reagent]
• Comins Reagent, N,N-Bis(trifluoromethylsulfonyl)-5-chloro-2-pyridylamine, 2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine

2-[N,N-Bis(trifluoromethanesulfonyl)amino]-5-chloropyridine [Triflating Reagent]

CAS: 145100-51-2

Fórmula: C₇H₃ClF₆N₂O₄S₂

Pureza: >96.0%(GC)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 392.67

Ref: 3B-B1865

2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine, 99%

CAS: 145100-51-2

2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine provides good yields of vinyl triflates from the corresponding ketone enolates or dienolates. It is used in the total synthesis of (-)-porantheridine and the trans decahydroquinoline alkaloid (+)-219A. It is also used as a reactant for Suzuk

Fórmula: C₇H₃ClF₆N₂O₄S₂

Pureza: 99%

Cor e Forma: White to pale yellow or cream, Crystalline powder

Peso molecular: 392.67

Ref: 02-L16929

Methanesulfonamide, N-(5-chloro-2-pyridinyl)-1,1,1-trifluoro-N-[(trifluoromethyl)sulfonyl]-

CAS: 145100-51-2

Fórmula: C₇H₃ClF₆N₂O₄S₂

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 392.6831

Ref: IN-DA001KJZ

2-{Bis[(trifluoromethyl)sulphonyl]amino}-5-chloropyridine

CAS: 145100-51-2

2-{Bis[(trifluoromethyl)sulphonyl]amino}-5-chloropyridine

Fórmula: C₇H₃ClF₆N₂O₄S₂

Pureza: ≥95%

Cor e Forma: Off-white Solid

Peso molecular: 392.68313

Ref: 54-PC3128

N-(5-Chloro-2-pyridyl)bis(trifluoromethanesulfonimide)

CAS: 145100-51-2

Fórmula: C₇H₃ClF₆N₂O₄S₂

Pureza: ≥ 98.0%

Cor e Forma: White to orange or brown powder or solid

Peso molecular: 392.68

Ref: 7W-GX3787

Comin's reagent

CAS: 145100-51-2

Comin's reagent is a sulfonation agent that reacts with an enolate and forms a sulfonic acid. The reaction can be used to synthesize chiral compounds. Comin's reagent is selective for the (R) configuration of acetylcholine and can be used to synthesize α-amino acids from chiral alcohols and esters. Comin's reagent is also used in the synthesis of neurotrophic or growth factor compounds, which are proteins that promote cell growth or differentiation. These functional groups are found in natural products such as nicotinic acetylcholine, thallusin, and growth factor.

Fórmula: C₇H₃ClF₆N₂O₄S₂

Pureza: Min. 95%

Cor e Forma: White Powder

Peso molecular: 392.68 g/mol

Ref: 3D-FC10786

2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine

CAS: 145100-51-2

2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine

Fórmula: C₇H₃ClF₆N₂O₄S₂

Pureza: 98%

Peso molecular: 392.68

Ref: IN-DG4062

2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine

CAS: 145100-51-2

Fórmula: C₇H₃ClF₆N₂O₄S₂

Pureza: 95%

Cor e Forma: Solid, Chunks or Crystalline Powder

Peso molecular: 392.67

Ref: 10-F009051

2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine

Produto Controlado

CAS: 145100-51-2

Stability Moisture Sensitive, Unstable in DMSO Solution
Applications 2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine also known as Comins’ Reagent is used as a triflyl compouind in the synthesis of vinyl triflates from metallo enolates.
References Comins, D., et al.: Tetrahedron Lett., 33, 6299 (1992);

Fórmula: C₇H₃ClF₆N₂O₄S₂

Cor e Forma: Neat

Peso molecular: 392.68

Ref: TR-B585565