CAS 1469284-79-4

Fórmula: C23H30ClN7O4S

InChI: InChI=1S/C22H26ClN7O.CH4O3S/c23-16-12-24-30(14-16)22(7-8-22)21-25-17-5-6-18(26-19(17)27-21)29-11-3-4-15(13-29)20(31)28-9-1-2-10-28;1-5(2,3)4/h5-6,12,14-15H,1-4,7-11,13H2,(H,25,26,27);1H3,(H,2,3,4)/t15-;/m1./s1

Chave InChI: ZSTFDNQQOJUJFL-XFULWGLBSA-N

SMILES: CS(=O)(=O)O.C1CCN(C1)C(=O)[C@@H]2CCCN(C2)C3=NC4=C(C=C3)NC(=N4)C5(CC5)N6C=C(C=N6)Cl

PF-06424439 methanesulfonate

CAS: 1469284-79-4

PF-06424439 methanesulfonate: oral, potent, selective DGAT2 inhibitor (IC50=14 nM), noncompetitive, slowly reversible.

Fórmula: C₂₃H₃₀ClN₇O₄S

Pureza: 99.77% - 99.9%

Cor e Forma: Solid

Peso molecular: 536.05

Ref: TM-T12425

(R)-(1-(2-(1-(4-Chloro-1H-pyrazol-1-yl)cyclopropyl)-1H-imidazo[4,5-b]pyridin-5-yl)piperidin-3-yl)(pyrrolidin-1-yl)methanone methanesulfonate

CAS: 1469284-79-4

Fórmula: C₂₃H₃₀ClN₇O₄S

Pureza: 99%

Peso molecular: 536.0468

Ref: IN-DA01ENIJ

PF-06424439 methanesulfonate

CAS: 1469284-79-4

PF-06424439 methanesulfonate

Fórmula: C₂₃H₃₀ClN₇O₄S

Pureza: ≥98%

Peso molecular: 536.05

Ref: 54-BUP08556

PF-06424439 methanesulfonate

CAS: 1469284-79-4

(R)-(1-(2-(1-(4-Chloro-1H-pyrazol-1-yl)cyclopropyl)-1H-imidazo[4,5-b]pyridin-5-yl)piperidin-3-yl)(pyrrolidin-1-yl)methanone methanesulfonate

Fórmula: C₂₃H₃₀ClN₇O₄S

Pureza: 99%

Peso molecular: 536.05

Ref: IN-DG01135008

PF 06424439

CAS: 1469284-79-4

PF 06424439 is a drug discovery tool for the study of ion channels. It is an antagonist of the nicotinic acetylcholine receptor (nAChR) and a partial agonist of the serotonin receptor 5-HT2B. PF 06424439 has been shown to block the activation of potassium channels in rat hippocampus, and it inhibits the proliferation of prostate cancer cells by blocking voltage-gated calcium channels. PF 06424439 binds to protein receptors in a ligand-receptor binding interaction, which can be used as a research tool in cell biology.

Fórmula: C₂₂H₂₆ClN₇O·CH₄O₃S

Pureza: Min. 95%

Peso molecular: 536.05 g/mol

Ref: 3D-UIC28479