CAS 149263-94-5

6'-metil-2-piridinil-2-(acetilamino)-2-desoxi-1-tio-B-D-glucopiranosídeo

Descrição:

6'-metil-2-piridinil-2-(acetilamino)-2-desoxi-1-tio-B-D-glucopiranosídeo, com o número CAS 149263-94-5, é um composto químico que pertence à classe dos glicosídeos, especificamente um tio-glicosídeo. Este composto apresenta um anel de piridina, que contribui para suas propriedades aromáticas, e um grupo tiol que substitui o oxigênio típico na ligação glicosídica, aumentando sua reatividade e potencial atividade biológica. A presença de um grupo acetilamino indica que pode participar de várias interações bioquímicas, potencialmente influenciando sua solubilidade e estabilidade. O grupo metila no anel de piridina pode afetar as propriedades eletrônicas do composto e a hindrance estérica, o que pode desempenhar um papel em sua interação com alvos biológicos. No geral, as características estruturais únicas deste composto sugerem aplicações potenciais em química medicinal, particularmente no desenvolvimento de terapias ou como uma sonda bioquímica, embora atividades biológicas específicas exijam investigação adicional.

Fórmula: C14H20N2O5S

InChI: InChI=1S/C14H20N2O5S/c1-7-4-3-5-10(15-7)22-14-11(16-8(2)18)13(20)12(19)9(6-17)21-14/h3-5,9,11-14,17,19-20H,6H2,1-2H3,(H,16,18)/t9-,11-,12-,13-,14+/m1/s1

Chave InChI: XUKXHOMZOIYNLR-FZGMBXNASA-N

SMILES: CC1=NC(=CC=C1)S[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)NC(=O)C

Sinónimos:

• Mpt-Nag
• 6-methyl-2-pyridinyl-2-(acetylamino)-2-deoxy-1-thio-β-D-glucopyranoside
• 6-Methyl-2-pyridinyl 2-(acetylamino)-2-deoxy-1-thio-beta-D-glucopyranoside

6-Methyl-2-pyridinyl 2-(acetylamino)-2-deoxy-1-thio-β-D-glucopyranoside

CAS: 149263-94-5

6-Methyl-2-pyridinyl 2-(acetylamino)-2-deoxy-1-thio-β-D-glucopyranoside

Fórmula: C₁₄H₂₀N₂O₅S

Pureza: ≥95%

Peso molecular: 328.38

Ref: 54-OR1129828

6-Methyl-2-pyridinyl 2-acetamido-2-deoxy-b-D-thioglucopyranoside

CAS: 149263-94-5

Ref: 7W-GC6100

6-Methyl-2-pyridyl 2-acetamido-2-deoxy-b-D-thioglucopyranoside

CAS: 149263-94-5

6-Methyl-2-pyridyl 2-acetamido-2-deoxy-b-D-thioglucopyranoside is a thioglycoside derivative featuring an N-acetyl-D-glucosamine moiety connected via a beta-thioglycosidic linkage to a 6-methyl-2-pyridyl aglycone. The thioether bond confers resistance to enzymatic hydrolysis by glycosidases while maintaining recognition by sugar-binding proteins. This thioglycoside is used as a stable substrate analog in glycosidase inhibition studies and as a probe for lectin-carbohydrate interaction mapping.

Fórmula: C₁₄H₂₀N₂O₅S

Peso molecular: 328.384

Ref: TM-TXB-00173

6-Methyl-2-pyridinyl 2-(acetylamino)-2-deoxy-1-thio-β-D-glucopyranoside

CAS: 149263-94-5

Fórmula: C₁₄H₂₀N₂O₅S

Pureza: 95%

Peso molecular: 328.3840

Ref: IN-DA001LIH

6-Methyl-2-pyridyl 2-acetamido-2-deoxy-b-D-thioglucopyranoside

CAS: 149263-94-5

The 6-Methyl-2-pyridyl 2-acetamido-2-deoxy-b-D-thioglucopyranoside is a chloride salt that has been used in the laboratory to develop an analytical method for the determination of glucose in urine samples. The bioavailability of 6MP is low and it is excreted by renal filtration, so this compound has been used as a marker for renal transplantation. Glomerular filtration rate (GFR) is reduced in diabetic patients, leading to a decrease in the amount of 6MP excreted. This drug can be administered orally or intravenously and has shown efficacy at low dose levels. Low doses have also been associated with decreased detection sensitivity due to its low level of excretion, which makes it an ideal candidate for use as a biomarker for chronic kidney disease. A chronic kidney disease animal model was used to study the effects on GFR and creatinine clearance rates

Pureza: Min. 95%

Cor e Forma: White Powder

Peso molecular: 328.39 g/mol

Ref: 3D-EM10847