CAS 149598-70-9

Fórmula: C23H30O5

InChI: InChI=1S/C23H30O5/c1-13-5-6-18-21(2,3)19(27)7-8-22(18,4)23(13)10-15-17(26)9-14(11-24)16(12-25)20(15)28-23/h9,11-13,18-19,26-27H,5-8,10H2,1-4H3/t13-,18+,19-,22+,23-/m1/s1

Chave InChI: WIGGVNIABVHHCS-QJAXDWLUSA-N

SMILES: C[C@@H]1CC[C@@H]2[C@@]([C@@]13CC4=C(C=C(C(=C4O3)C=O)C=O)O)(CC[C@H](C2(C)C)O)C

Mer-NF5003F

CAS: 149598-70-9

Mer-NF5003F (Stachybotrydial; F 1839M) is a sesquiterpene isolated from Stachybotrys, effective in inhibiting avian myeloblastosis virus (AMV) protease with an IC₅₀ of 7.8 μM. It also inhibits sialyltransferases ST6N, ST3O, and ST3N with IC₅₀ values of 0.61, 6.7, and 10 μg/mL, respectively, and fucosyltransferase with an IC₅₀ of 11.3 μg/mL. Additionally, Mer-NF5003F exhibits in vitro activity against herpes simplex virus HSV-1 (IC₅₀=4.32 μg/mL) and multi-drug-resistant Plasmodium falciparum K1 strain (IC₅₀=0.85 μg/mL).

Fórmula: C₂₃H₃₀O₅

Cor e Forma: Solid

Peso molecular: 386.4813

Ref: TM-T208688