
CAS 152551-75-2
:Fórmula:C19H27N5O4
InChI:InChI=1S/C19H27N5O4/c1-4-5-14(25)18(26)23-6-8-24(9-7-23)19-21-13-11-16(28-3)15(27-2)10-12(13)17(20)22-19/h10-11,14,25H,4-9H2,1-3H3,(H2,20,21,22)
Chave InChI:WHIHPZQGQNXDKE-UHFFFAOYSA-N
SMILES:CCCC(C(=O)N1CCN(CC1)C2=NC3=CC(=C(C=C3C(=N2)N)OC)OC)O
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Foram encontrados 6 produtos.
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Terazosin EP Impurity J
CAS:Fórmula:C19H27N5O4Cor e Forma:White To Off-White SolidPeso molecular:389.461-[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-hydroxy-1-pentanone
CAS:Produto ControladoImpurity Terazosin EP Impurity J
Applications 1-[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-hydroxy-1-pentanone (Terazosin EP Impurity J) is an impurity of Terazosin (T105000), an α-1-adrenergic blocker that is related to Prazosin (P702325).
References Blom, Y., et al.: J. Chromatograph., 653, 138 (1993);Fórmula:C19H27N5O4Cor e Forma:NeatPeso molecular:389.451-[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-hydroxy-1-pentanone-d8
CAS:Produto ControladoApplications Isotope labelled 1-[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-hydroxy-1-pentanone s an impurity of Terazosin (T105000), an α-1-adrenergic blocker that is related to Prazosin (P702325).
References Blom, Y., et al.: J. Chromatograph., 653, 138 (1993);Fórmula:C19D8H19N5O4Cor e Forma:NeatPeso molecular:397.4981-[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-hydroxy-1-pentanone
CAS:1-[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-hydroxy-1-pentanone (DMPP) is an analog of the antiarrhythmic drugs flecainide and propafenone. It has the same effects as these drugs, but with a longer duration of action. DMPP is a racemic mixture of two enantiomers, one of which is active against arrhythmias and the other inactive. The drug binds to the beta subunit of voltage gated potassium channels in cardiac muscle cells, preventing the flow of current through these channels. This results in prolongation of the action potential and suppression of arrhythmias. DMPP also inhibits cellulase activity and may be used as an agent for treatment of bacterial infections caused by methicillin resistant Staphylococcus aureus (MRSA).Fórmula:C19H27N5O4Pureza:Min. 95%Peso molecular:389.45 g/mol1-[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-hydroxy-1-pentanone
CAS:Fórmula:C19H27N5O4Cor e Forma:SolidPeso molecular:389.4488




