CAS 1551460-43-5

Fórmula: C31H29ClF2N4O4

InChI: InChI=1S/C31H29ClF2N4O4/c1-17-4-3-5-26(38-13-11-19(15-27(38)39)28-23(33)9-8-22(32)29(28)34)25-14-18(10-12-35-25)21-7-6-20(36-31(41)42-2)16-24(21)37-30(17)40/h6-10,12,14-17,26H,3-5,11,13H2,1-2H3,(H,36,41)(H,37,40)/t17-,26-/m1/s1

Chave InChI: AXXYATYQRMPQSN-WGDIFIGCSA-N

SMILES: C[C@@H]1CCC[C@H](C2=NC=CC(=C2)C3=C(C=C(C=C3)NC(=O)OC)NC1=O)N4CCC(=CC4=O)C5=C(C=CC(=C5F)Cl)F

FXIa-IN-6

CAS: 1551460-43-5

FXIa-IN-6: Potent, selective FXIa inhibitor (Ki=0.3 nM); strong PK with high oral bioavailability, low clearance preclinically.

Fórmula: C₃₁H₂₉ClF₂N₄O₄

Cor e Forma: Solid

Peso molecular: 595.04

Ref: TM-T39035