CAS 15622-65-8

Cloridrato de molindona

Descrição:

Cloridrato de molindona é um medicamento antipsicótico utilizado principalmente no tratamento da esquizofrenia. Pertence à classe de compostos conhecidos como derivados do indol e exibe um mecanismo de ação único, funcionando principalmente como um antagonista dos receptores de dopamina. Este composto é caracterizado por sua capacidade de modular a atividade dos neurotransmissores no cérebro, o que ajuda a aliviar os sintomas associados a distúrbios psicóticos. Cloridrato de molindona é tipicamente administrado em sua forma de sal hidroclorídrico, melhorando sua solubilidade e biodisponibilidade. A substância é conhecida por seus efeitos sedativos relativamente baixos em comparação com outros antipsicóticos, tornando-se uma opção preferida para alguns pacientes. Além disso, possui um perfil de efeitos colaterais favorável, embora ainda possa causar sintomas extrapiramidais e outros efeitos adversos. A estrutura química inclui um anel de piperidina, contribuindo para suas propriedades farmacológicas. Assim como qualquer medicamento, é essencial que os pacientes sejam monitorados quanto à eficácia e aos efeitos colaterais durante o tratamento.

Fórmula: C₁₆H₂₅ClN₂O₂

InChI: InChI=1/C16H24N2O2.ClH/c1-3-13-11(2)17-14-5-4-12(16(19)15(13)14)10-18-6-8-20-9-7-18;/h12,17H,3-10H2,1-2H3;1H

Chave InChI: InChIKey=GQWNECFJGBQMBO-UHFFFAOYSA-N

SMILES: C(C)C=1C2=C(NC1C)CCC(CN3CCOCC3)C2=O.Cl

Sinónimos:

• 3-Ethyl-2-methyl-5-(morpholinomethyl)-6,7-dihydro-1H-indol-4(5H)-one hydrochloride
• 3-Ethyl-2-methyl-5-[(morpholin-4-yl)methyl]-4,5,6,7-tetrahydro-1H-indol-4-one hydrochloride
• 3-Ethyl-6,7-Dihydro-2-Methyl-5-(Morpholinomethyl)-Indol-4(5H)-Onmonohydroc
• 3-Ethyl-6,7-Dihydro-2-Methyl-5-Morpholinomethylindol-4(5H)-Onehydrochloride
• 3-Ethyl-6,7-Dihydro-2-Methyl-5-Morpholinomethylindole-4(5H)-Onehydrochloride
• 4-[(3-ethyl-2-methyl-4-oxo-4,5,6,7-tetrahydro-1H-indol-5-yl)methyl]morpholin-4-ium chloride
• 4H-Indol-4-one, 3-ethyl-1,5,6,7-tetrahydro-2-methyl-5-(4-morpholinylmethyl)-, hydrochloride (1:1)
• 4H-Indol-4-one, 3-ethyl-1,5,6,7-tetrahydro-2-methyl-5-(4-morpholinylmethyl)-, monohydrochloride
• En 1733A
• Indol-4(5H)-one, 3-ethyl-6,7-dihydro-2-methyl-5-(morpholinomethyl)-, monohydrochloride
• Lidone
• Lindone
• Moban
• Molindone hydrochloride
• MOLINDONE HCL USP/EP/BP
• MolindoneHydrochloride&gt
• MOBAN;EN-1733A
• MOLINDONE HYDROCHLORIDE (500 MG)
• 3-Ethyl-1,5,6,7-tetrahydro-2-methyl-5-(4-morpholinylmethyl)-4H-indol-4-one, hydrochloride (1:1)(For export only)
• Molindone Hydrochloride (1445459)
• 3-Ethyl-1,5,6,7-tetrahydro-2-methyl-5-(4-morpholinylmethyl)-4H-indol-4-one, hydrochloride (1:1)
• Molindone Hydrochlorid
• 3-Ethyl-6,7-dihydro-2-methyl-5-(morpholinomethyl)-1H-indol-4(5H)-one Hydrochloride

Molindone Hydrochloride

CAS: 15622-65-8

Fórmula: C₁₆H₂₄N₂O₂·HCl

Pureza: >98.0%(HPLC)(T)

Cor e Forma: White to Yellow to Orange powder to crystal

Peso molecular: 312.84

Ref: 3B-M2252

Molindone Hydrochloride

CAS: 15622-65-8

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Fórmula: C₁₆H₂₄N₂O₂·HCl

Cor e Forma: White Off-White Powder

Peso molecular: 276.18378

Ref: 45-1445459

Molindone hydrochloride

CAS: 15622-65-8

Molindone hydrochloride (EN-1733A) is an indole derivative effective in schizophrenia and other psychoses by blocking the effects of dopamine in the brain.

Fórmula: C₁₆H₂₅ClN₂O₂

Pureza: 99% - 99.99%

Cor e Forma: Solid

Peso molecular: 312.835

Ref: TM-T0716

Molindone hydrochloride

CAS: 15622-65-8

Molindone hydrochloride

Fórmula: C₁₆H₂₄N₂O₂·HCl

Pureza: 99.5%

Peso molecular: 312.84

Ref: 54-BUP13668

Molindone hydrochloride

CAS: 15622-65-8

Molindone hydrochloride

Fórmula: C₁₆H₂₅ClN₂O₂

Pureza: 0.98

Peso molecular: 312.83

Ref: 54-OR1026824

Molindone HCl

CAS: 15622-65-8

Fórmula: C₁₆H₂₄N₂O₂·HCl

Cor e Forma: Off-White Solid

Peso molecular: 276.38 36.46

Ref: 4Z-M-155001

Molindone hydrochloride

CAS: 15622-65-8

Fórmula: C₁₆H₂₄N₂O₂·HCl

Pureza: ≥ 98.0%

Cor e Forma: White to off-white solid

Peso molecular: 312.83

Ref: 7W-GP8140

Molindone.HCl, 1mg/ml in Methanol (as free base)

CAS: 15622-65-8

Fórmula: C₁₆H₂₄N₂O₂·ClH

Cor e Forma: Colourless

Peso molecular: 312.83

Ref: LP-MOL-1886-HC-1LM

Molindone.HCl

CAS: 15622-65-8

Fórmula: C₁₆H₂₄N₂O₂·ClH

Cor e Forma: Neat

Peso molecular: 312.83

Ref: LP-MOL-1886-HC

Molindone Hydrochloride

Produto Controlado

CAS: 15622-65-8

Applications D2 Dopamine receptor antagonist. MAO inhibitor. Antipsychotic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Sugerman, H., et al.: Clin. Pharmacol. Ther., 8, 261 (1967), Claghorn, et al.: Curr. Ther. Res., 11, 524 (1969), Goldenthal, E.I., et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971),

Fórmula: C₁₆H₂₄N₂O₂·ClH

Cor e Forma: Neat

Peso molecular: 312.83

Ref: TR-M487500

3-Ethyl-2-methyl-5-(morpholinomethyl)-6,7-dihydro-1H-indol-4(5H)-one hydrochloride

CAS: 15622-65-8

3-Ethyl-2-methyl-5-(morpholinomethyl)-6,7-dihydro-1H-indol-4(5H)-one hydrochloride

Fórmula: C₁₆H₂₅ClN₂O₂

Pureza: 99%

Peso molecular: 312.83

Ref: IN-DG140247

Molindone hydrochloride

CAS: 15622-65-8

Fórmula: C₁₆H₂₅ClN₂O₂

Pureza: >98.0%(HPLC)(T)

Peso molecular: 312.84

Ref: 10-F494213

Molindone hydrochloride

CAS: 15622-65-8

Molindone is a neuroleptic agent that has been shown to be effective in the treatment of schizophrenia. It also has antipsychotic properties and may treat other mental disorders. Molindone is a potent dopamine antagonist, which is thought to explain its therapeutic effects in these conditions. The drug is well absorbed orally and crosses the blood-brain barrier easily, making it suitable for oral administration. Molindone has been shown to have toxic effects in animal studies, including a decrease in serum prolactin levels, an increase in liver weights, and an increase in the number of animals that died during toxicity studies. These side-effect profiles are similar to those seen with haloperidol (a phenothiazine antipsychotic), which suggests that molindone may be used as an alternative to haloperidol when treating psychosis or other mental disorders.

Fórmula: C₁₆H₂₄N₂O₂•HCl

Pureza: Min. 95%

Cor e Forma: White To Light (Or Pale) Yellow To Light (Or Pale) Red Solid

Peso molecular: 312.83 g/mol

Ref: 3D-FM55422

Molindone hydrochloride

CAS: 15622-65-8

Fórmula: C₁₆H₂₅ClN₂O₂

Peso molecular: 312.83

Ref: BE-RMCM232001

Molindone Hydrochloride

CAS: 15622-65-8

Fórmula: C₁₆H₂₄N₂O₂HCl

Peso molecular: 276.4 : 36.46

Ref: ST-EA-CP-M43006

4H-Indol-4-one, 3-ethyl-1,5,6,7-tetrahydro-2-methyl-5-(4-morpholinylmethyl)-, hydrochloride (1:1)

CAS: 15622-65-8

Fórmula: C₁₆H₂₅ClN₂O₂

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 312.8349

Ref: IN-DA001OM4