CAS 1575596-29-0

Fórmula: C36H40FN9O3

InChI: InChI=1S/C36H40FN9O3/c1-36(2,45-15-13-43(14-16-45)26-21-48-22-26)18-24(19-38)35(47)44-12-6-7-25(20-44)46-34-31(33(39)40-23-41-34)32(42-46)29-11-10-28(17-30(29)37)49-27-8-4-3-5-9-27/h3-5,8-11,17-18,23,25-26H,6-7,12-16,20-22H2,1-2H3,(H2,39,40,41)/b24-18-/t25-/m1/s1

Chave InChI: LCFFREMLXLZNHE-IURUZKCNSA-N

SMILES: CC(C)(/C=C(/C#N)\C(=O)N1CCC[C@H](C1)N2C3=NC=NC(=C3C(=N2)C4=C(C=C(C=C4)OC5=CC=CC=C5)F)N)N6CCN(CC6)C7COC7

Rilzabrutinib

CAS: 1575596-29-0

Rilzabrutinib (PRN1008) is a reversible covalent, selective and oral active inhibitor of Bruton’s Tyrosine Kinase (BTK)(IC50 of 1.3 nM).

Fórmula: C₃₆H₄₀FN₉O₃

Pureza: 98.28% - 99.76%

Cor e Forma: White Solid

Peso molecular: 665.7597

Ref: TM-T12542

Rilzabrutinib

CAS: 1575596-29-0

Rilzabrutinib

Fórmula: C₃₆H₄₀FN₉O₃

Pureza: 99.5%

Peso molecular: 665.76

Ref: 54-BUP08990

Rilzabrutinib

CAS: 1575596-29-0

(R,E)-2-(3-(4-Amino-3-(2-fluoro-4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carbonyl)-4-methyl-4-(4-(oxetan-3-yl)piperazin-1-yl)pent-2-enenitrile

Fórmula: C₃₆H₄₀FN₉O₃

Pureza: 99.0%

Peso molecular: 665.76

Ref: IN-DG00812358

Rilzabrutinib

CAS: 1575596-29-0

Fórmula: C₃₆H₄₀FN₉O₃

Peso molecular: 665.77

Ref: 4Z-R-193001

PRN1008

CAS: 1575596-29-0

PRN1008 is a small molecule that acts as an inhibitor of methyltransferases. It is a powerful, irreversible inhibitor of the enzyme and has shown to be efficacious in treating infectious diseases such as tuberculosis and malaria. PRN1008 has also been shown to be effective in treating autoimmune diseases, cancer, and inflammatory diseases. The drug is currently undergoing clinical trials for its effects on hematopoietic cells and activity index.

Fórmula: C₃₆H₄₀FN₉O₃

Pureza: (Lc-Ms) Min. 98 Area-%

Cor e Forma: Powder

Peso molecular: 665.76 g/mol

Ref: 3D-FP167893