CAS 1627856-64-7

Fórmula: C22H21F4N3O4

InChI: InChI=1S/C22H21F4N3O4/c1-4-32-16-9-19(30)27-11-14(16)12-5-6-13(15(23)7-12)8-20(31)28-18-10-17(33-29-18)21(2,3)22(24,25)26/h5-7,9-11H,4,8H2,1-3H3,(H,27,30)(H,28,29,31)

Chave InChI: IDXKJSSOUXWLDB-UHFFFAOYSA-N

SMILES: CCOC1=CC(=O)NC=C1C2=CC(=C(C=C2)CC(=O)NC3=NOC(=C3)C(C)(C)C(F)(F)F)F

GSK3179106

CAS: 1627856-64-7

GSK3179106

Fórmula: C₂₂H₂₁F₄N₃O₄

Pureza: ≥98%

Peso molecular: 467.41

Ref: 54-BUP09107

2-(4-(4-Ethoxy-6-Oxo-1,6-Dihydropyridin-3-Yl)-2-Fluorophenyl)-N-(5-(1,1,1-Trifluoro-2-Methylpropan-2-Yl)Isoxazol-3-Yl)Acetamide

CAS: 1627856-64-7

2-(4-(4-Ethoxy-6-Oxo-1,6-Dihydropyridin-3-Yl)-2-Fluorophenyl)-N-(5-(1,1,1-Trifluoro-2-Methylpropan-2-Yl)Isoxazol-3-Yl)Acetamide

Fórmula: C₂₂H₂₁F₄N₃O₄

Pureza: 99%

Peso molecular: 467.41

Ref: 54-PC108424

GSK3179106

CAS: 1627856-64-7

Fórmula: C₂₂H₂₁F₄N₃O₄

Pureza: 99%

Peso molecular: 467.4135

Ref: IN-DA01EO4W

GSK3179106

CAS: 1627856-64-7

2-(4-(4-Ethoxy-6-oxo-1,6-dihydropyridin-3-yl)-2-fluorophenyl)-N-(5-(1,1,1-trifluoro-2-methylpropan-2-yl)isoxazol-3-yl)acetamide

Fórmula: C₂₂H₂₁F₄N₃O₄

Pureza: 99%

Peso molecular: 467.41

Ref: IN-DG00818920

GSK3179106

CAS: 1627856-64-7

GSK3179106 is RET kinase inhibitor with an IC50 of 0.4 nM

Fórmula: C₂₂H₂₁F₄N₃O₄

Pureza: 99.8% - 99.90%

Cor e Forma: Solid

Peso molecular: 467.4135

Ref: TM-T5491

2-(4-(4-ETHOXY-6-OXO-1,6-DIHYDROPYRIDIN-3-YL)-2-FLUOROPHENYL)-N-(5-(1,1,1-TRIFLUORO-2-METHYLPROPAN-2-YL)ISOXAZOL-3-YL)ACETAMIDE

CAS: 1627856-64-7

Pureza: 99%

Peso molecular: 467.42099

Ref: 10-F833520

GSK3179106

CAS: 1627856-64-7

GSK3179106 is a potent and selective inhibitor of the enzyme GSK3. It has been shown to have effects on acetylcholine levels, which may be due to its ability to modulate choline uptake. GSK3179106 has also been shown to inhibit cancerous growth by blocking the activation of the EGFR mutant in ganglion cells. This drug binds with high affinity to the receptor for acetylcholine at the neuromuscular junction and blocks neuronal function.

Fórmula: C₂₂H₂₁F₄N₃O₄

Pureza: Min. 95%

Peso molecular: 467.41 g/mol

Ref: 3D-CQC85664