CAS 165806-63-3

Fórmula: C19H20FN3O

InChI: InChI=1S/C19H20FN3O/c1-2-24-13-3-12-23-14-22-18(15-4-6-17(20)7-5-15)19(23)16-8-10-21-11-9-16/h4-11,14H,2-3,12-13H2,1H3

Chave InChI: HSHCBSSOMDJQKJ-UHFFFAOYSA-N

SMILES: CCOCCCN1C=NC(=C1C2=CC=NC=C2)C3=CC=C(C=C3)F

TNF-α-IN-26

CAS: 165806-63-3

TNF-α-IN-26 (Compound 18) is a TNF-α inhibitor, exhibiting an IC50 of 0.10 μM for the CSBP ligand. It suppresses LPS-stimulated TNF production in mouse models and is applicable in research on inflammatory diseases.

Fórmula: C₁₉H₂₀FN₃O

Peso molecular: 325.38

Ref: TM-T212524