CAS 166108-71-0

Ácido 8-(9-fluorenilmetoxicarbonilamino)-3,6-dioxaoctanoico

Descrição:

Ácido 8-(9-fluorenilmetoxicarbonilamino)-3,6-dioxaoctanoico, comumente referido como Fmoc-D-OAA, é um composto sintético utilizado principalmente na síntese de peptídeos e como grupo protetor para aminoácidos. Esta substância apresenta uma estrutura de ácido dioxaoctanoico, que contribui para sua solubilidade e estabilidade em vários solventes. A presença do grupo fluorenilmetoxicarbonilo (Fmoc) permite a proteção seletiva do grupo amino, facilitando a montagem passo a passo de peptídeos. Fmoc-D-OAA é caracterizado por sua capacidade de sofrer desproteção em condições básicas suaves, tornando-o vantajoso na síntese de peptídeos em fase sólida. Além disso, o composto exibe boa compatibilidade com vários reagentes de acoplamento e pode ser utilizado na síntese de peptídeos bioativos. Sua estrutura inclui regiões hidrofílicas e hidrofóbicas, que podem influenciar sua interação com sistemas biológicos. No geral, Fmoc-D-OAA é uma ferramenta valiosa no campo da química orgânica e bioquímica, particularmente no desenvolvimento de terapias baseadas em peptídeos.

Fórmula: C₂₁H₂₃NO₆

InChI: InChI=1/C21H23NO6/c23-20(24)14-27-12-11-26-10-9-22-21(25)28-13-19-17-7-3-1-5-15(17)16-6-2-4-8-18(16)19/h1-8,19H,9-14H2,(H,22,25)(H,23,24)

Chave InChI: InChIKey=XQPYRJIMPDBGRW-UHFFFAOYSA-N

SMILES: C(OC(NCCOCCOCC(O)=O)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2

Sinónimos:

• (2-[2-(9H-Fluoren-9-Ylmethoxycarbonylamino)-Ethoxy]-Ethoxy)-Acetic Acid
• 1-(9H-Fluoren-9-Yl)-3-Oxo-2,7,10-Trioxa-4-Azadodecan-12-Oic Acid
• 1-(9H-Fuoren-9-Yl)-3-Oxo-2,7,10-Trioxa-4-Azadodecan-12-Oic Acid
• 12-(9H-Fluoren-9-yl)-10-oxo-3,6,11-trioxa-9-azadodecanoic acid
• 2,7,10-Trioxa-4-azadodecan-12-oic acid, 1-(9H-fluoren-9-yl)-3-oxo-
• 2-[2-[2-(9H-Fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]acetic acid
• 2-[2-[2-([[(9H-Fluoren-9-yl)methoxy]carbonyl]amino)ethoxy]ethoxy]acetic acid
• 3,6,11-Trioxa-9-azadodecanoic acid, 12-(9H-fluoren-9-yl)-10-oxo-
• 8-(9-Fluorenylmethoxycarbonyl-Amino)-3,6-Dioxa-Octanoic Acid
• 8-(9-Fluorenylmethoxycarbonylamino)-3,6-dioxaoctanoic acid
• 8-(Fmoc-Amino)-3,6-Dioxa-Octanoic Acid
• 8-(Fmoc-amino)-3,6-dioxaoctanoic acid
• 8-Fluorenylmethoxycarbonylamino-3,6-Dioxaoctanoic Acid
• 9-Fluorenylmethoxycarbonyl-8-Amino-3,6-Dioxaoctanoic Acid
• Fmoc-Aeea-Oh
• Fmoc-Aeeac-Oh
• Fmoc-NH-PEG₂-CH₂COOH
• Fmoc-aeea
• Rarechem Em Wb 0032
• (2-[2-(Fmoc-Amino)-Ethoxy]-Ethoxy)-Acetic Acid
• FMOC-[2-(2-AMINO-ETHOXY)-ETHOXY]-ACETIC ACID
• FMOC-8-AMINO-3,6-DIOXAOCTANOIC ACID
• FMOC-O2OC-OH
• 8-(9-Fluorenylmethyloxycarbonyl-amino)-3,6-dioxaoctanoicacid,{2-[2-(Fmoc-amino)ethoxy]ethoxy}aceticacid,1-(9H-Fuoren
• FMOC-MINI-PEG(TM)
• 8-(9-FLUOROENYLMETHYLOXYCARBONYL-AMINO)-3,6-DIOXAOCTANOIC ACID
• 8-(9-Fluorenylmethyloxycarbonyl-amino)-3,6-dioxaoctanoic acid, {2-[2-(Fmoc-amino)ethoxy]ethoxy}acetic acid, 1-(9H-Fuoren-9-yl)-3-oxo-2,7,10-trioxa-4-azadodecan-12-oic acid, Fmoc-Ado, Fmoc-AEEA
• 8-(9-FLUORENYLMETHYLOXYCARBONYL-AMINO)-3,6-DIOXAOCTANOIC ACID

8-[(9H-Fluoren-9-ylmethoxy)carbonylamino]-3,6-dioxa-n-octanoic Acid

CAS: 166108-71-0

Fórmula: C₂₁H₂₃NO₆

Pureza: >97.0%(HPLC)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 385.42

Ref: 3B-F0719

(2-[2-(Fmoc-amino)ethoxy]ethoxy)acetic acid, 95%

CAS: 166108-71-0

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₂₁H₂₃NO₆

Pureza: 95%

Peso molecular: 385.42

Ref: 02-H63641

Fmoc-AEEAc-OH

CAS: 166108-71-0

Hydrophilic heterobifunctional spacer useful to attach chromophores. Building block for the synthesis of spacers of defined length.

Fórmula: C₂₁H₂₃NO₆

Pureza: 99.9%

Cor e Forma: White

Peso molecular: 385.42

Ref: 01-4037914

Fmoc-8-amino-3,6-dioxaoctanoic acid

CAS: 166108-71-0

Fmoc-8-amino-3,6-dioxaoctanoic acid (Fmoc-NH-PEG2-CH2COOH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Fórmula: C₂₁H₂₃NO₆

Pureza: 99.61%

Cor e Forma: White Crystal

Peso molecular: 385.41

Ref: TM-T15304

{2[2-(Fmoc-amino)ethoxy]ethoxy}acetic acid

CAS: 166108-71-0

{2[2-(Fmoc-amino)ethoxy]ethoxy}acetic acid

Fórmula: C₂₁H₂₃NO₆

Pureza: 98%

Cor e Forma: White Solid-Powder

Peso molecular: 385.41041

Ref: 54-OR0969

3,6,11-Trioxa-9-azadodecanoic acid, 12-(9H-fluoren-9-yl)-10-oxo-

CAS: 166108-71-0

Fórmula: C₂₁H₂₃NO₆

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 385.4104

Ref: IN-DA001WHY

Fmoc-8-amino-3,6-dioxaoctanoic acid

CAS: 166108-71-0

Fmoc-8-amino-3,6-dioxaoctanoic acid

Fórmula: C₂₁H₂₃NO₆

Pureza: ≥98%

Cor e Forma: Solid

Peso molecular: 385.41

Ref: 54-BUP19698

Fmoc-AEEA-OH

CAS: 166108-71-0

1-(9H-Fluoren-9-yl)-3-oxo-2,7,10-trioxa-4-azadodecan-12-oic acid

Fórmula: C₂₁H₂₃NO₆

Pureza: 98%

Peso molecular: 385.41

Ref: IN-DG130882

Fmoc-mini-PEG Fmoc-8-Amino-3,6-Dioxaoctanoic Acid

CAS: 166108-71-0

Fmoc-mini-PEG Fmoc-8-Amino-3,6-Dioxaoctanoic Acid is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), these types of compounds are more versatile as they have two different anchor points. Fmoc-mini-PEG Fmoc-8-Amino-3,6-Dioxaoctanoic Acid is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules, and nanoparticles. It is enzyme-cleavable via β-glucuronidase, releasing the drug or payload in enzyme-rich environments.

Fórmula: C₂₁H₂₃NO₆

Pureza: Min. 95%

Peso molecular: 385.42 g/mol

Ref: 3D-FXX-5521-PI

Fmoc-AEEA

CAS: 166108-71-0

This PEGylated Fmoc linker is used for controlled conjugation of biomolecules. The cleavage occurs under chemical or enzymatic conditions.

Fórmula: C₂₁H₂₃NO₆

Pureza: Min. 97.5 Area-%

Cor e Forma: Powder

Peso molecular: 385.41 g/mol

Ref: 3D-FF35496

Fmoc-Amino-3,6 dioxaoctanoic acid

CAS: 166108-71-0

Fórmula: C₂₁H₂₃NO₆

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 385.416

Ref: 10-F050302

8-(Fmoc-amino)-3,6-dioxaoctanoic Acid

Produto Controlado

CAS: 166108-71-0

Applications 8-(Fmoc-amino)-3,6-dioxaoctanoic Acid is a hydrophilic, heterobifunctional spacer.
References Koskinen, A., et al.: Bioorg. Med. Chem. Lett., 5, 573 (1995)

Fórmula: C₂₁H₂₃NO₆

Cor e Forma: Neat

Peso molecular: 385.41

Ref: TR-F603515