CAS 16937-99-8

tert-Butiloxicarbonil-D-leucina

Descrição:

tert-Butiloxicarbonil-D-leucina, comumente abreviado como Boc-D-leucina, é um derivado do aminoácido leucina, caracterizado pela presença de um grupo protetor de tert-butiloxicarbonila (Boc). Este composto é tipicamente utilizado na síntese de peptídeos como um grupo protetor para a funcionalidade amino, o que ajuda a prevenir reações indesejadas durante o processo de síntese. O grupo Boc é conhecido por sua estabilidade em condições básicas e pode ser facilmente removido em condições ácidas, tornando-se uma escolha popular na síntese orgânica. tert-Butiloxicarbonil-D-leucina é um sólido branco a off-white, e sua estrutura molecular inclui uma cadeia lateral alifática ramificada, característica da leucina, que contribui para suas propriedades hidrofóbicas. O composto é solúvel em solventes orgânicos como diclorometano e dimetilformamida, mas tem solubilidade limitada em água. Suas aplicações se estendem além da síntese de peptídeos para incluir estudos em bioquímica e química medicinal, onde serve como um bloco de construção para vários compostos bioativos.

Fórmula: C₁₁H₂₁NO₄

InChI: InChI=1S/C11H21NO4/c1-7(2)6-8(9(13)14)12-10(15)16-11(3,4)5/h7-8H,6H2,1-5H3,(H,12,15)(H,13,14)/t8-/m1/s1

Chave InChI: InChIKey=MDXGYYOJGPFFJL-MRVPVSSYSA-N

SMILES: [C@@H](NC(OC(C)(C)C)=O)(CC(C)C)C(O)=O

Sinónimos:

• (2R)-2-[[(tert-Butoxy)carbonyl]amino]-4-methylpentanoic acid
• (2R)-4-Methyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoic acid
• (R)-2-(tert-Butoxycarbonylamino)-4-methylpentanoic acid
• (R)-2-[[tert-Butoxycarbonyl)amino]-4-methylpentanoicacid
• (R)-N-(t-Butoxycarbonyl)leucine
• <span class="text-smallcaps">D</span>-Boc leucine
• <span class="text-smallcaps">D</span>-Leucine, N-[(1,1-dimethylethoxy)carbonyl]-
• Boc-D-Leu-OH hydrate
• Boc-D-Leu-OH.H2O
• Boc-D-Leu-Oh
• Boc-D-Leucine
• L-Leucine-5,5,5-D3, N-T-Boc Deriv.H20
• Leucine, N-carboxy-, N-tert-butyl ester, <span class="text-smallcaps">D</span>-
• N-(Tert-Butoxycarbonyl)-D-Leucine
• N-(tert-Butoxycarbonyl)-<span class="text-smallcaps">D</span>-leucine
• N-(tert-butoxycarbonyl)-D-leucine hydrate
• N-Alpha-T-Boc-D-Leucine
• N-Boc-<span class="text-smallcaps">D</span>-leucine
• N-Boc-D-Leu-OH monohydrate
• N-T-Boc-D-Leucine
• N-Tert-Butoxycarbonyl-D-Leucine 1-Hydrate
• N-[(1,1-Dimethylethoxy)carbonyl]-<span class="text-smallcaps">D</span>-leucine
• tert-Butoxycarbonyl-<span class="text-smallcaps">D</span>-leucine
• Leucine, N-carboxy-, N-tert-butyl ester, D-
• N-[(1,1-Dimethylethoxy)carbonyl]-D-leucine
• D-Leucine, N-[(1,1-dimethylethoxy)carbonyl]-

N-Boc-D-leucine hydrate, 98+%

CAS: 16937-99-8

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₁₁H₂₃NO₅

Pureza: 98+%

Cor e Forma: Crystals or powder or crystalline powder, White

Peso molecular: 249.31

Ref: 02-L09124

Boc-D-Leu-OH · H₂O

CAS: 16937-99-8

Bachem ID: 4002976.

Fórmula: C₁₁H₂₁NO₄·H₂O

Pureza: > 99%

Cor e Forma: White

Peso molecular: 249.31

Ref: 01-4002976

Boc-D-Leu-OH

CAS: 16937-99-8

Fórmula: C₁₁H₂₁NO₄xH₂O

Peso molecular: 231.29

Ref: 7W-GM6632

Boc-D-leucine

CAS: 16937-99-8

Boc-D-leucine

Fórmula: C₁₁H₂₁NO₄

Pureza: >98%

Peso molecular: 231.28874

Ref: 54-OR452082

BOC-D-Leucine monohydrate

CAS: 16937-99-8

Fórmula: C₁₁H₂₃NO₅

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 249.3040

Ref: IN-DA00IKJ0

N-Boc-D-leucine

Produto Controlado

CAS: 16937-99-8

Applications N-Boc-D-leucine is an N-Boc-protected form of D-Leucine (L330150). D-Leucine is an unnatural isomer of L-Leucine (L330110) that acts as an auto-inhibitor of lactic streptococci in culture. D-Leucine causes analgesia in humans and also exhibits inhibitory activity in bacterial cell cultures.
References Chuan, Y., et al.: Chin. J. Anim. Vet. Sci., 4, 003 (1985); Fox, S., et al.: J. Biol. Chem., 155, 465 (1944); Gillillad, S. & Speck, M.: J. Dairy Sci., 51, 1573 (1968); Schoenheimer, R., et al.: J. Biol. Chem., 130, 703 (1939); Seltzer, S., et al.: Pain, 11, 141 (1981)

Fórmula: C₁₁H₂₁NO₄

Cor e Forma: Neat

Peso molecular: 231.29

Ref: TR-B656800

Boc-D-Leu-OH

CAS: 16937-99-8

Boc-D-Leu-OH

Fórmula: C₁₁H₂₁NO₄

Pureza: 95%

Peso molecular: 231.29

Ref: IN-DG294155

Boc-D-Leu-OH • H2O

CAS: 16937-99-8

Boc-D-Leu-OH • H2O is an intramolecular hydrogen. It has a helical structure and forms hydrogen bonds with other molecules. Boc-D-Leu-OH • H2O is a cyclic peptide with a hydrophobic side chain and a hydrophilic head group. The peptide has been shown to have antimicrobial activity in the biliary and intestinal tract, as well as chronic pain relief properties. Boc-D-Leu-OH • H2O was found to be effective in animal studies for neuropathic pain, which may be due to its amide structure. A silico analysis revealed that the drug substance had a high binding affinity for the mu opioid receptor and could potentially be used to treat chronic pain caused by inflammation.

Fórmula: C₁₁H₂₁NO₄•H₂O

Pureza: Min. 95%

Peso molecular: 249.31 g/mol

Ref: 3D-BDL-2603

Boc-D-Leu-OH

CAS: 16937-99-8

M03296 - Boc-D-Leu-OH

Fórmula: C₁₁H₂₁NO₄

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 231.292

Ref: 10-M03296

BOC-D-Leucine extrapure, 98%

CAS: 16937-99-8

Fórmula: C₁₁H₂₁NO₄

Pureza: min. 98%

Cor e Forma: White, Crystalline powder

Peso molecular: 231.30

Ref: SR-22237

Boc-D-Leu-OH

CAS: 16937-99-8

Boc-D-Leu-OH is a cyclic peptide that has been shown to have antibacterial activity. It is a monomer with a hydroxy group and a cavity. Boc-D-Leu-OH was found to be able to transport hydrophobic compounds across membranes, which may be due to its hydrophobic nature. Boc-D-Leu-OH also induces apoptosis in cells, which can lead to cancer. This compound has been optimized by structural modifications and residue substitutions, which have led to improved properties such as enhanced stability and increased antimicrobial activity.

Fórmula: C₁₁H₂₁NO₄

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 231.29 g/mol

Ref: 3D-RAA93799