CAS 171596-29-5

Tadalafila

Descrição:

Tadalafila é um inibidor da fosfodiesterase tipo 5 (PDE5) utilizado principalmente para o tratamento da disfunção erétil e da hipertensão arterial pulmonar. É caracterizado pela sua capacidade de aumentar o fluxo sanguíneo ao relaxar os vasos sanguíneos no pênis, facilitando uma ereção em resposta à estimulação sexual. Tadalafila tem uma longa meia-vida, permitindo efeitos prolongados, que podem durar até 36 horas, ganhando o apelido de "a pílula do fim de semana". A estrutura química de Tadalafila inclui uma estrutura bicíclica com um anel de pirimidina, contribuindo para suas propriedades farmacológicas. É tipicamente administrado por via oral e está disponível em várias dosagens. Tadalafila é geralmente bem tolerado, mas pode causar efeitos colaterais como dores de cabeça, rubor e dispepsia. É importante notar que Tadalafila não deve ser usado em conjunto com nitratos devido ao risco de hipotensão severa. No geral, Tadalafila representa um avanço significativo no manejo da disfunção erétil e condições relacionadas, proporcionando aos pacientes uma opção terapêutica confiável.

Fórmula: C₂₂H₁₉N₃O₄

InChI: InChI=1S/C22H19N3O4/c1-24-10-19(26)25-16(22(24)27)9-14-13-4-2-3-5-15(13)23-20(14)21(25)12-6-7-17-18(8-12)29-11-28-17/h2-8,16,21,23H,9-11H2,1H3/t16-,21-/m1/s1

Chave InChI: InChIKey=WOXKDUGGOYFFRN-IIBYNOLFSA-N

SMILES: O=C1N2[C@@H](C3=C(C=4C(N3)=CC=CC4)C[C@@]2(C(=O)N(C)C1)[H])C=5C=C6C(=CC5)OCO6

Sinónimos:

• (6R,12Ar)-6-(1,3-Benzodioxol-5-Yl)-2,3,6,7,12,12A-Hexahydro-2-Methyl-Pyrazino[1',2':1,6]Pyrido[3,4-B]Indole-1,4-Dione
• (6R,12aR)-2,3,6,7,12,12a-hexahydro-2-methyl-6-(3,4-methylenedioxyphenyl)pyrazino[1′,2′:1,6]pyrido[3,4-b]indole-1,4-dione
• (6R,12aR)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methylpyrazino[1′,2′:1,6]pyrido[3,4-b]indole-1,4-dione
• (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2-methyl-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione
• (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2-methyl-3,4,6,6a,7,11b,12,12a-octahydropyrazino[1',2':1,6]pyrido[3,4-b]indol-1(2H)-one
• Adcirca
• Cialis
• Gf 196960
• Ic-351
• Icos 351
• Lifta
• Pentadafil
• Pyrazino[1′,2′:1,6]pyrido[3,4-b]indole-1,4-dione, 6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-, (6R,12aR)-
• Pyrazino[1′,2′:1,6]pyrido[3,4-b]indole-1,4-dione, 6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-, (6R-trans)-
• Tadalafil Lilly
• Tadanafil
• Tadfil
• Tadora
• Talmanco
• Tardenafil
• Tildenafil
• Uk 336017

Tadalafil

CAS: 171596-29-5

Fórmula: C₂₂H₁₉N₃O₄

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 389.41

Ref: 3B-T4029

TADALAFIL CRS

CAS: 171596-29-5

TADALAFIL CRS

Fórmula: C₂₂H₁₉N₃O₄

Peso molecular: 389.404

Ref: 41-Y0001417

Tadalafil

CAS: 171596-29-5

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Fórmula: C₂₂H₁₉N₃O₄

Cor e Forma: White Off-White Powder

Peso molecular: 389.13756

Ref: 45-1642879

Tadalafil

CAS: 171596-29-5

Tadalafil (IC-351) is a carboline-based compound with vasodilatory activity.

Fórmula: C₂₂H₁₉N₃O₄

Pureza: 97.03%

Cor e Forma: Off-White Cyrstalline Solid

Peso molecular: 389.40

Ref: TM-T1398

Tadalafil

CAS: 171596-29-5

Fórmula: C₂₂H₁₉N₃O₄

Pureza: ≥ 98%

Cor e Forma: White to light-yellow powder

Peso molecular: 389.40

Ref: 7W-GP0380

Tadalafil

CAS: 171596-29-5

Fórmula: C₂₂H₁₉N₃O₄

Cor e Forma: White To Off-White Solid

Peso molecular: 389.41

Ref: 4Z-T-103

Cialis

CAS: 171596-29-5

Cialis

Fórmula: C₂₂H₁₉N₃O₄

Pureza: 99%

Cor e Forma: Solid

Peso molecular: 389.4

Ref: 54-OR1026996

Tadalafil

CAS: 171596-29-5

Tadalafil

Fórmula: C₂₂H₁₉N₃O₄

Pureza: ≥95%

Peso molecular: 389.4

Ref: 54-BUP17162

Tadalafil

CAS: 171596-29-5

Fórmula: C₂₂H₁₉N₃O₄

Cor e Forma: Neat

Peso molecular: 389.40

Ref: 04-C17133000

Tadalafil 1.0 mg/ml in Acetonitrile

CAS: 171596-29-5

Cor e Forma: Single Solution

Ref: 61-AMP0806.00-11

Tadalafil

CAS: 171596-29-5

Cor e Forma: Neat

Ref: 86-MM0806.00

Tadalafil

CAS: 171596-29-5

Fórmula: C₂₂H₁₉N₃O₄

Peso molecular: 389.41

Ref: ST-EA-CP-T31000

Tadalafil

Produto Controlado

CAS: 171596-29-5

Stability Unstable in Methanol
Applications Tadalafil is used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor.
References Carrier, S., et al.: Can. J. Urol., 10(1), 12 (2003); Doggrell, S.A., et al.: Expert Opin. Pharmacother., 6, 75 (2005); Forgue, S.T., et al.: Br. J. Clin. Pharmacol., 61, 280 (2005);

Fórmula: C₂₂H₁₉N₃O₄

Cor e Forma: Neat

Peso molecular: 389.4

Ref: TR-T004500

Tadalafil - Bio-X ™

CAS: 171596-29-5

Tadalafil is a phosphodiesterase (PDE) inhibitor used to treat erectile dysfunction. It works by inhibiting the enzyme PDE, which is responsible for breaking down cGMP, a molecule that relaxes smooth muscle cells in the penis and allows for increased blood flow. Tadalafil has an ability to also act as a channel inhibitor and nerve growth factor inhibitor. Additionally, it is said to aid with pulmonary arterial hypertension by relaxing the blood vessels in the lungs to allow blood to flow more easily.

Fórmula: C₂₂H₁₉N₃O₄

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 389.4 g/mol

Ref: 3D-BT164435

Tadalafil

CAS: 171596-29-5

Tadalafil is a phosphodiesterase type 5 inhibitor that is used to treat erectile dysfunction by increasing blood flow to the penis. It is an oral drug that blocks the enzyme phosphodiesterase type 5 (PDE5) and increases the levels of cyclic guanosine monophosphate (cGMP) in smooth muscle cells, leading to vasodilation and increased blood flow. Tadalafil has been shown to be effective in men with pulmonary hypertension and primary pulmonary hypertension. Tadalafil also has a side-effect profile similar to other PDE5 inhibitors, including headache, dizziness, nausea, nasal congestion or runny nose, indigestion, diarrhea or constipation, back pain and muscle pain. This drug also interacts with drugs that can cause serious adverse effects if taken with PDE5 inhibitors. Tadalafil is not active against bacteria; therefore it cannot be used for the treatment of bacterial infections such as tuberculosis.

Fórmula: C₂₂H₁₉N₃O₄

Pureza: (Hplc) Min. 98%

Cor e Forma: White Powder

Peso molecular: 389.4 g/mol

Ref: 3D-FB02802

Tadalafil

CAS: 171596-29-5

Ref: BE-BePure-25739

Tadalafil in Methanol

CAS: 171596-29-5

Methanol

Ref: BE-BePure-25739YM-1000

Tadalafil-13C2,d3

Produto Controlado

CAS: 171596-29-5

Applications Tadalafil-13C2,d3 is labelled Tadalafil (T004500) which is used for the treatment of erectile dysfunction. It is a phosphodiesterase 5 inhibitor.
References Carrier, S., et al.: Can. J. Urol., 10(1), 12 (2003), Doggrell, S.A., et al.: Expert Opin. Pharmacother., 6, 75 (2005), Forgue, S.T., et al.: Br. J. Clin. Pharmacol., 61, 280 (2005)

Fórmula: C₂₀₁₃C₂H₁₆D₃N₃O₄

Cor e Forma: Neat

Peso molecular: 394.41

Ref: TR-T004502

2-Triethylmethyl Tadalafil

Produto Controlado

CAS: 171596-29-5

Fórmula: C₂₇H₂₉N₃O₄

Cor e Forma: Neat

Peso molecular: 459.537

Ref: TR-T776663