CAS 17406-45-0

Tomatina

Descrição:

Tomatina é um composto de glicoalcaloide encontrado principalmente em tomates e em certos outros membros da família Solanaceae. É caracterizado por seu sabor amargo e é conhecido por seus potenciais benefícios à saúde, incluindo propriedades antifúngicas e antimicrobianas. Tomatina possui uma estrutura molecular complexa, apresentando uma espinha dorsal esteroidal com um grupo de açúcar, o que contribui para sua solubilidade e atividade biológica. O composto exibe uma variedade de efeitos biológicos, incluindo a capacidade de inibir o crescimento de certos patógenos e possivelmente modular os níveis de colesterol. Embora Tomatina seja geralmente considerado seguro nas quantidades normalmente consumidas em tomates, pode ser tóxico em altas concentrações, particularmente em tomates não maduros. Sua presença em tomates gerou interesse em seu papel nos mecanismos de defesa das plantas e em possíveis aplicações na preservação de alimentos e suplementos de saúde. No geral, Tomatina representa uma área intrigante de estudo dentro da fitoquímica e nutrição, destacando as complexas interações entre compostos vegetais e a saúde humana.

Fórmula: C₅₀H₈₃NO₂₁

InChI: InChI=1S/C50H83NO21/c1-20-7-12-50(51-15-20)21(2)32-28(72-50)14-26-24-6-5-22-13-23(8-10-48(22,3)25(24)9-11-49(26,32)4)65-45-40(63)37(60)41(31(18-54)68-45)69-47-43(71-46-39(62)36(59)34(57)29(16-52)66-46)42(35(58)30(17-53)67-47)70-44-38(61)33(56)27(55)19-64-44/h20-47,51-63H,5-19H2,1-4H3/t20-,21-,22-,23-,24+,25-,26-,27+,28-,29+,30+,31+,32-,33-,34+,35+,36-,37+,38+,39+,40+,41-,42-,43+,44-,45+,46-,47-,48-,49-,50-/m0/s1

Chave InChI: InChIKey=REJLGAUYTKNVJM-SGXCCWNXSA-N

SMILES: C[C@@]12[C@@]3([C@](C[C@]1([C@]4([C@](CC2)([C@]5(C)[C@@](CC4)(C[C@@H](O[C@@H]6O[C@H](CO)[C@H](O[C@H]7[C@H](O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@@H](O[C@H]9[C@H](O)[C@@H](O)[C@H](O)CO9)[C@H](O)[C@@H](CO)O7)[C@H](O)[C@H]6O)CC5)[H])[H])[H])[H])(O[C@]%10([C@H]3C)CC[C@H](C)CN%10)[H])[H]

Sinónimos:

• (3beta,5alpha,22beta,25S)-Spirosolan-3-yl O-beta-D-glucopyranosyl-(1-2)-O-(beta-D-xylopyranosyl)-(1-3))-O-(beta-D-glucopyranosyl-(1-4)-beta-D-Galactopyranoside
• (3beta,5alpha,25S)-spirosolan-3-yl beta-D-glucopyranosyl-(1->2)-[beta-D-xylopyranosyl-(1->3)]-beta-D-glucopyranosyl-(1->4)-beta-D-galactopyranoside
• (3β,5α,22β,25S)-Spirosolan-3-yl O-β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-(1→2)-O-[β-<smallcap>D</smallcap>-xylopyranosyl-(1→3)]-O-β-<smallcap>D</smallcap>-glucopyranosyl-(1→4)-β-<smallcap>D</span>-galactopyranoside
• A''-Tomatidine
• Ai3-17141
• Brn 0078250
• Hsdb 3558
• Lycopersicin
• Nsc 234440
• Nsc 9223
• Spiro[8H-naphth[2′,1′:4,5]indeno[2,1-b]furan-8,2′-piperidine], β-<span class="text-smallcaps">D</span>-galactopyranoside deriv.
• Spirosolane, β-<span class="text-smallcaps">D</span>-galactopyranoside deriv.
• Tomatidine, glycoside
• Tomatin
• alpha-Tomatine
• beta-D-Galactopyranoside, (3beta,5alpha,22beta,25S)-spirosolan-3-yl O-beta-D-glucopyranosyl-(1-2)-O-(beta-D-xylopyranosyl-(1-3))-O-beta-D-glucopyranosyl-(1-4)-
• α-Tomatine
• β-<span class="text-smallcaps">D</smallcap>-Galactopyranoside, (3β,5α,22β,25S)-spirosolan-3-yl O-β-<smallcap>D</smallcap>-glucopyranosyl-(1→2)-O-[β-<smallcap>D</smallcap>-xylopyranosyl-(1→3)]-O-β-<smallcap>D</span>-glucopyranosyl-(1→4)-
• Spirosolane, β-D-galactopyranoside deriv.
• 4-27-00-01954 (Beilstein Handbook Reference)
• β-D-Galactopyranoside, (3β,5α,22β,25S)-spirosolan-3-yl O-β-D-glucopyranosyl-(1→2)-O-[β-D-xylopyranosyl-(1→3)]-O-β-D-glucopyranosyl-(1→4)-
• Tomatine

Tomatine from Tomato

CAS: 17406-45-0

Fórmula: C₅₀H₈₃NO₂₁

Pureza: >80.0%(HPLC)

Cor e Forma: White to Yellow to Orange powder to crystal

Peso molecular: 1,034.20

Ref: 3B-T3636

Tomatine

CAS: 17406-45-0

Fórmula: C₅₀H₈₃NO₂₁

Pureza: ≥ 95.0%

Cor e Forma: Off-white to light yellow powder

Peso molecular: 1034.18

Ref: 7W-GC5426

Tomatine

CAS: 17406-45-0

Fórmula: C₅₀H₈₃NO₂₁

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 1034.1881

Ref: IN-DA001ZFB

Tomatine

CAS: 17406-45-0

Tomatine analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Fórmula: C₅₀H₈₃NO₂₁

Pureza: (HPLC) ≥95%

Cor e Forma: Powder

Peso molecular: 1034.21

Ref: 11-0602

Tomatine

CAS: 17406-45-0

Fórmula: C₅₀H₈₃NO₂₁

Pureza: 95%~99%

Peso molecular: 1034.2

Ref: BP-BP1726

Tomatine (85%)

CAS: 17406-45-0

Fórmula: C₅₀H₈₃NO₂₁

Pureza: 85%

Cor e Forma: Neat

Peso molecular: 1034.19

Ref: TR-T538510

Tomatine

CAS: 17406-45-0

(2S,3R,4S,5S,6R)-2-(((2S,3R,4S,5R,6R)-2-(((2R,3R,4R,5R,6R)-4,5-Dihydroxy-2-(hydroxymethyl)-6-(((2aS,4S,5'S,6aS,6bS,8aS,8bR,9S,10S,11aS,12aS,12bR)-5',6a,8a,9-tetramethyloctadecahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2'-piperidin]-4-yl)oxy)tetra

Fórmula: C₅₀H₈₃NO₂₁

Pureza: 98%

Peso molecular: 1034.19

Ref: IN-DG154387

Tomatine

CAS: 17406-45-0

Tomatine (lycopersicin) is an antiproliferatve agent of breast adenocarcinoma cells.

Fórmula: C₅₀H₈₃NO₂₁

Pureza: 98.42% - 99.93%

Cor e Forma: Solid

Peso molecular: 1034.1881

Ref: TM-T3786

Tomatine

CAS: 17406-45-0

Natural alkaloid

Fórmula: C₅₀H₈₃NO₂₁

Pureza: ≥ 95.0 % (HPLC)

Cor e Forma: Powder

Peso molecular: 1034.21

Ref: 5G-89905

Tomatine

CAS: 17406-45-0

Tomatine is a glycoalkaloid, which is a secondary metabolite found in tomato plants (Solanum lycopersicum). It is primarily synthesized in the leaves and stems, serving as a natural defense mechanism against pathogens. The mode of action of tomatine involves disrupting the cell membranes of microbes, leading to leakage of cellular components and eventual cell death. This disruption is due to its ability to form complexes with sterols, which are vital components of microbial membranes.

Fórmula: C₅₀H₈₃NO₂₁

Pureza: Min. 75 Area-%

Cor e Forma: White Powder

Peso molecular: 1,034.19 g/mol

Ref: 3D-OT07656

Tomatine

CAS: 17406-45-0

Fórmula: C₅₀H₈₃NO₂₁

Peso molecular: 1034.2

Ref: BE-RMT13446

Tomatine (Standard)

CAS: 17406-45-0

Tomatine (Standard) is a reference standard. Tomatine upregulates AIF and inhibits 20S proteasome activity, inducing neurotoxicity.

Fórmula: C₅₀H₈₃NO₂₁

Peso molecular: 1034.1881

Ref: TM-TMSM-1509