CAS 17692-51-2

metergolina

Descrição:

metergolina é um composto químico classificado como um antagonista do receptor de serotonina, direcionando-se principalmente ao subtipo de receptor 5-HT2. É conhecido por suas potenciais aplicações no campo da neurociência e psicofarmacologia, particularmente no estudo de transtornos de humor e condições psicóticas. metergolina exibe uma estrutura complexa que inclui um grupo indol, que é característico de muitos compostos relacionados à serotonina. A substância é tipicamente administrada em ambientes de pesquisa, e seu perfil farmacológico sugere que pode influenciar vários sistemas de neurotransmissores, potencialmente afetando o humor e a percepção. metergolina foi investigado por seus efeitos em vias de serotonina centrais e periféricas, contribuindo para seu interesse em contextos terapêuticos. No entanto, como muitos compostos nesta categoria, também pode apresentar efeitos colaterais e requer consideração cuidadosa em termos de dosagem e administração. Assim como qualquer agente farmacológico, a pesquisa contínua é essencial para entender completamente seus mecanismos de ação e potenciais benefícios terapêuticos.

Fórmula: C₂₅H₂₉N₃O₂

InChI: InChI=1/C25H29N3O2/c1-27-14-18(13-26-25(29)30-16-17-7-4-3-5-8-17)11-21-20-9-6-10-22-24(20)19(12-23(21)27)15-28(22)2/h3-10,15,18,21,23H,11-14,16H2,1-2H3,(H,26,29)/p+1/t18-,21+,23+/m0/s1

Chave InChI: InChIKey=WZHJKEUHNJHDLS-QTGUNEKASA-N

SMILES: CN1C2=C3C([C@@]4([C@@](CC3=C1)(N(C)C[C@H](CNC(OCC5=CC=CC=C5)=O)C4)[H])[H])=CC=C2

Sinónimos:

• (((8-beta)-1,6-Dimethylergolin-8-yl)methyl)carbamic acid phenylmethyl ester
• (+)-N-(Carboxy)-1-methyl-9,10-dihydrolysergamine benzyl ester
• (+)-N-Carboxy-1-methyl-9,10-dihydrolysergamide benzyl ester
• 1,6-Dimethyl-8-beta-carbobenzyloxaminomethyl-10-alpha-ergoline
• 1-Methyl-8-beta-carbobenzyloxyaminomethyl-10-alpha-ergoline
• 1-Methyl-N-carbobenzyloxydihydro-D-lysergamin
• 8β-Carbobenzyloxyaminomethyl-1,6-dimethyl-10α-ergoline
• <span class="text-smallcaps">D</span>-8β-[(Carbobenzoxyamino)methyl]-1,6-dimethyl-10α-ergoline
• <span class="text-smallcaps">D</span>-8β-[(Carboxyamino)methyl]-1,6-dimethylergoline I benzyl ester
• <span class="text-smallcaps">D</span>-N-Carbobenzoxydihydro-1-methyllysergamine I
• <span class="text-smallcaps">D</span>-N-Carboxydihydro-1-methyllysergamine I benzyl ester
• <span class="text-smallcaps">D</span>-[(4,6,6a,7,8,9,10,10a-Octahydro-4,7-dimethyl-10aα-indolo[4,3-fg]quinolin-9β-yl)methyl]carbamic acid benzyl ester
• Ahr 3009
• Benzyl 1,6-dimethylergolin-8beta-ylmethylcarbamat
• Benzyl {[(5Xi,10Beta)-1,6-Dimethylergolin-8-Yl]Methyl}Carbamate
• Benzyl {[(8Beta)-1,6-Dimethylergolin-6-Ium-8-Yl]Methyl}Carbamate
• Benzyl {[(8Beta)-1,6-Dimethylergolin-8-Yl]Methyl}Carbamate
• Carbamic acid, (((8-beta)-1,6-dimethylergolin-8-yl)methyl)-, benzyl ester
• Carbamic acid, (((8-beta)-1,6-dimethylergolin-8-yl)methyl)-, phenylmethyl ester (9CI)
• Carbamic acid, (((8beta)-1,6-dimethylergolin-8-yl)methyl)-, phenylmethyl ester
• Carbamic acid, ((1,6-dimethylergolin-8-beta-yl)methyl)-, benzyl ester
• Carbamic acid, N-[[(8β)-1,6-dimethylergolin-8-yl]methyl]-, phenylmethyl ester
• Carbamic acid, [(1,6-dimethylergolin-8β-yl)methyl]-, benzyl ester
• Carbamic acid, [[(8β)-1,6-dimethylergolin-8-yl]methyl]-, phenylmethyl ester
• Contralac
• D-8-beta-((Carbobenzoxyamino)methyl)-1,6-dimethyl-10-alpha-ergoline
• D-8-beta-((Carboxyamino)methyl)-1,6-dimethylergoline I benzyl ester
• D-N-Carbobenzoxydihydro-1-methyllysergamine I
• D-N-Carboxydihydro-1-methyllysergamine I benzyl ester
• Ergoline, carbamic acid deriv.
• Fi 6337
• Indolo[4,3-fg]quinoline, carbamic acid deriv.
• Liserdol
• Lysergamine, N-carboxy-9,10-dihydro-1-methyl-, benzyl ester
• Lysergamine, N-carboxy-9,10-dihydro-1-methyl-, benzyl ester (7CI)
• MCE
• Metergolin
• Metergolina
• Metergolina [DCIT]
• Metergolina [Spanish]
• Metergoline [INN:BAN]
• Metergolinum
• Metergolinum [INN-Latin]
• Metergolinum [Latin]
• Methergoline
• Substance 355/255
• Unii-1501393Ly5
• Metergoline
• [((8BETA)-1,6-DIMETHYLERGOLIN-8-YL)METHYL]CARBAMIC ACID PHENYLMETHYL ESTER
• (((8-beta)-1,6-dimethylergolin-8-yl)methyl)-carbamicaciphenylmethylest
• d-n-carbobenzoxydihydro-1-methyllysergaminei
• ((1,6-dimethylergolin-8-beta-yl)methyl)-carbamicacibenzylester
• d-n-carboxydihydro-1-methyllysergamineibenzylester
• ahr3009
• N-CBZ-[(8BETA)-1,6-DIMETHYLERGOLIN-8-YL]METHYLAMINE
• (((8-beta)-1,6-dimethylergolin-8-yl)methyl)-carbamicacibenzylester
• METERGOLINE PHENYLMETHYL ESTER

Metergoline

CAS: 17692-51-2

Fórmula: C₂₅H₂₉N₃O₂

Pureza: 99%

Cor e Forma: Solid

Peso molecular: 403.5167

Ref: IN-DA0078UU

Metergoline

CAS: 17692-51-2

Metergoline

Pureza: ≥98%

Peso molecular: 403.52g/mol

Ref: 54-BUP16416

Metergoline

CAS: 17692-51-2

Fórmula: C₂₅H₂₉N₃O₂

Peso molecular: 403.52

Ref: 7W-GP3682

Metergoline

CAS: 17692-51-2

Metergoline (Methergoline) is a dopamine agonist and serotonin antagonist.

Fórmula: C₂₅H₂₉N₃O₂

Pureza: 99.83% - 99.97%

Cor e Forma: Solid

Peso molecular: 403.52

Ref: TM-T4008

Metergoline

CAS: 17692-51-2

Applications Metergoline is an antagonist at 5-HT1, 5-HT2, and 5-HT7 serotonin receptors. Metergoline is an analgesic; antipyretic.
References Aulakh, et al.: J. Pharmacol. Exp. Ther., 263, 588 (1992), Miller, et al.: Eur. J. Pharmacol., 227, 99 (1992),

Fórmula: C₂₅H₂₉N₃O₂

Cor e Forma: Off White Powder

Peso molecular: 403.5167

Ref: TR-M226270

[(8b)-1,6-Dimethylergolin-8-yl)methyl]carbamic acid phenylmethyl ester

CAS: 17692-51-2

Ergolines are a class of drugs that bind to serotonin receptors. The ergoline derivative [(8b)-1,6-dimethylergolin-8-yl)methyl]carbamic acid phenylmethyl ester (DMPE) is a potent and selective 5-hydroxytryptamine (5-HT) receptor antagonist. DMPE has been shown to have the ability to increase serum prolactin levels in rats and antagonize the effects of metergoline in monkeys. It also reduces blood pressure in animals by blocking the vasoconstrictor effect of 5-HT on vascular smooth muscle cells.

Fórmula: C₂₅H₂₉N₃O₂

Pureza: Min. 95%

Cor e Forma: White Powder

Peso molecular: 403.52 g/mol

Ref: 3D-FM12444