CAS 17692-51-2
:metergolina
Descrição:
metergolina é um composto químico classificado como um antagonista do receptor de serotonina, direcionando-se principalmente ao subtipo de receptor 5-HT2. É conhecido por suas potenciais aplicações no campo da neurociência e psicofarmacologia, particularmente no estudo de transtornos de humor e condições psicóticas. metergolina exibe uma estrutura complexa que inclui um grupo indol, que é característico de muitos compostos relacionados à serotonina. A substância é tipicamente administrada em ambientes de pesquisa, e seu perfil farmacológico sugere que pode influenciar vários sistemas de neurotransmissores, potencialmente afetando o humor e a percepção. metergolina foi investigado por seus efeitos em vias de serotonina centrais e periféricas, contribuindo para seu interesse em contextos terapêuticos. No entanto, como muitos compostos nesta categoria, também pode apresentar efeitos colaterais e requer consideração cuidadosa em termos de dosagem e administração. Assim como qualquer agente farmacológico, a pesquisa contínua é essencial para entender completamente seus mecanismos de ação e potenciais benefícios terapêuticos.
Fórmula:C25H29N3O2
InChI:InChI=1/C25H29N3O2/c1-27-14-18(13-26-25(29)30-16-17-7-4-3-5-8-17)11-21-20-9-6-10-22-24(20)19(12-23(21)27)15-28(22)2/h3-10,15,18,21,23H,11-14,16H2,1-2H3,(H,26,29)/p+1/t18-,21+,23+/m0/s1
Chave InChI:InChIKey=WZHJKEUHNJHDLS-QTGUNEKASA-N
SMILES:CN1C2=C3C([C@@]4([C@@](CC3=C1)(N(C)C[C@H](CNC(OCC5=CC=CC=C5)=O)C4)[H])[H])=CC=C2
Sinónimos:- (((8-beta)-1,6-Dimethylergolin-8-yl)methyl)carbamic acid phenylmethyl ester
- (+)-N-(Carboxy)-1-methyl-9,10-dihydrolysergamine benzyl ester
- (+)-N-Carboxy-1-methyl-9,10-dihydrolysergamide benzyl ester
- 1,6-Dimethyl-8-beta-carbobenzyloxaminomethyl-10-alpha-ergoline
- 1-Methyl-8-beta-carbobenzyloxyaminomethyl-10-alpha-ergoline
- 1-Methyl-N-carbobenzyloxydihydro-D-lysergamin
- 8β-Carbobenzyloxyaminomethyl-1,6-dimethyl-10α-ergoline
- <span class="text-smallcaps">D</span>-8β-[(Carbobenzoxyamino)methyl]-1,6-dimethyl-10α-ergoline
- <span class="text-smallcaps">D</span>-8β-[(Carboxyamino)methyl]-1,6-dimethylergoline I benzyl ester
- <span class="text-smallcaps">D</span>-N-Carbobenzoxydihydro-1-methyllysergamine I
- <span class="text-smallcaps">D</span>-N-Carboxydihydro-1-methyllysergamine I benzyl ester
- <span class="text-smallcaps">D</span>-[(4,6,6a,7,8,9,10,10a-Octahydro-4,7-dimethyl-10aα-indolo[4,3-fg]quinolin-9β-yl)methyl]carbamic acid benzyl ester
- Ahr 3009
- Benzyl 1,6-dimethylergolin-8beta-ylmethylcarbamat
- Benzyl {[(5Xi,10Beta)-1,6-Dimethylergolin-8-Yl]Methyl}Carbamate
- Benzyl {[(8Beta)-1,6-Dimethylergolin-6-Ium-8-Yl]Methyl}Carbamate
- Benzyl {[(8Beta)-1,6-Dimethylergolin-8-Yl]Methyl}Carbamate
- Carbamic acid, (((8-beta)-1,6-dimethylergolin-8-yl)methyl)-, benzyl ester
- Carbamic acid, (((8-beta)-1,6-dimethylergolin-8-yl)methyl)-, phenylmethyl ester (9CI)
- Carbamic acid, (((8beta)-1,6-dimethylergolin-8-yl)methyl)-, phenylmethyl ester
- Carbamic acid, ((1,6-dimethylergolin-8-beta-yl)methyl)-, benzyl ester
- Carbamic acid, N-[[(8β)-1,6-dimethylergolin-8-yl]methyl]-, phenylmethyl ester
- Carbamic acid, [(1,6-dimethylergolin-8β-yl)methyl]-, benzyl ester
- Carbamic acid, [[(8β)-1,6-dimethylergolin-8-yl]methyl]-, phenylmethyl ester
- Contralac
- D-8-beta-((Carbobenzoxyamino)methyl)-1,6-dimethyl-10-alpha-ergoline
- D-8-beta-((Carboxyamino)methyl)-1,6-dimethylergoline I benzyl ester
- D-N-Carbobenzoxydihydro-1-methyllysergamine I
- D-N-Carboxydihydro-1-methyllysergamine I benzyl ester
- Ergoline, carbamic acid deriv.
- Fi 6337
- Indolo[4,3-fg]quinoline, carbamic acid deriv.
- Liserdol
- Lysergamine, N-carboxy-9,10-dihydro-1-methyl-, benzyl ester
- Lysergamine, N-carboxy-9,10-dihydro-1-methyl-, benzyl ester (7CI)
- MCE
- Metergolin
- Metergolina
- Metergolina [DCIT]
- Metergolina [Spanish]
- Metergoline [INN:BAN]
- Metergolinum
- Metergolinum [INN-Latin]
- Metergolinum [Latin]
- Methergoline
- Substance 355/255
- Unii-1501393Ly5
- Metergoline
- [((8BETA)-1,6-DIMETHYLERGOLIN-8-YL)METHYL]CARBAMIC ACID PHENYLMETHYL ESTER
- (((8-beta)-1,6-dimethylergolin-8-yl)methyl)-carbamicaciphenylmethylest
- d-n-carbobenzoxydihydro-1-methyllysergaminei
- ((1,6-dimethylergolin-8-beta-yl)methyl)-carbamicacibenzylester
- d-n-carboxydihydro-1-methyllysergamineibenzylester
- ahr3009
- N-CBZ-[(8BETA)-1,6-DIMETHYLERGOLIN-8-YL]METHYLAMINE
- (((8-beta)-1,6-dimethylergolin-8-yl)methyl)-carbamicacibenzylester
- METERGOLINE PHENYLMETHYL ESTER
- Ver mais sinónimos
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Foram encontrados 8 produtos.
Metergoline
CAS:Metergoline (Methergoline) is a dopamine agonist and serotonin antagonist.Fórmula:C25H29N3O2Pureza:99.83% - 99.97%Cor e Forma:SolidPeso molecular:403.52Metergoline
CAS:Applications Metergoline is an antagonist at 5-HT1, 5-HT2, and 5-HT7 serotonin receptors. Metergoline is an analgesic; antipyretic.
References Aulakh, et al.: J. Pharmacol. Exp. Ther., 263, 588 (1992), Miller, et al.: Eur. J. Pharmacol., 227, 99 (1992),Fórmula:C25H29N3O2Cor e Forma:NeatPeso molecular:403.5167[(8b)-1,6-Dimethylergolin-8-yl)methyl]carbamic acid phenylmethyl ester
CAS:Ergolines are a class of drugs that bind to serotonin receptors. The ergoline derivative [(8b)-1,6-dimethylergolin-8-yl)methyl]carbamic acid phenylmethyl ester (DMPE) is a potent and selective 5-hydroxytryptamine (5-HT) receptor antagonist. DMPE has been shown to have the ability to increase serum prolactin levels in rats and antagonize the effects of metergoline in monkeys. It also reduces blood pressure in animals by blocking the vasoconstrictor effect of 5-HT on vascular smooth muscle cells.Fórmula:C25H29N3O2Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:403.52 g/mol
![[(8b)-1,6-Dimethylergolin-8-yl)methyl]carbamic acid phenylmethyl ester](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb%2FFM12444.jpg&w=3840&q=75)
