CAS 1779796-27-8

Fórmula: C22H28ClNO5

InChI: InChI=1S/C22H27NO5.ClH/c1-22(2,3)17-11-15(16-6-8-19-20(12-16)28-14-27-19)5-7-18(17)26-10-9-23(4)13-21(24)25;/h5-8,11-12H,9-10,13-14H2,1-4H3,(H,24,25);1H

Chave InChI: ZQVOAGQZHDAFRM-UHFFFAOYSA-N

SMILES: CC(C)(C)C1=C(C=CC(=C1)C2=CC3=C(C=C2)OCO3)OCCN(C)CC(=O)O.Cl

LY2365109 hydrochloride

CAS: 1779796-27-8

LY2365109 hydrochloride is a potent and selective GlyT1 inhibitor, with an IC50 of 15.8 nM for glycine uptake in cells over-expressing hGlyT1a.

Fórmula: C₂₂H₂₈ClNO₅

Pureza: 98.27%

Cor e Forma: White Solid

Peso molecular: 421.91

Ref: TM-T11908

LY2365109 (hydrochloride)

CAS: 1779796-27-8

Fórmula: C₂₂H₂₈ClNO₅

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 421.9144

Ref: IN-DA00ABSO

LY2365109 hydrochloride

CAS: 1779796-27-8

LY2365109 hydrochloride

Fórmula: C₂₂H₂₈ClNO₅

Pureza: ≥98%

Peso molecular: 421.91

Ref: 54-BUP09483

LY2365109 hydrochloride

CAS: 1779796-27-8

LY2365109 hydrochloride is a drug for the treatment of depression. It blocks glutamate uptake by the neurotransmitter transporter type, which leads to an increase in extracellular glutamate concentrations and consequently an increase in neuronal excitability, leading to an improvement in symptoms. LY2365109 hydrochloride has been shown to be effective against depression in a clinical response assay. This drug also has a role in the treatment of skin conditions and food composition. LY2365109 hydrochloride binds to the glutamate transporter and inhibits the uptake of this neurotransmitter by neurons. This binding leads to an increase in extracellular glutamate concentrations, which then lead to an increase in neuronal excitability and thereby alleviation of depressive symptoms.

Fórmula: C₂₂H₂₈ClNO₅

Pureza: Min. 95%

Peso molecular: 421.91 g/mol

Ref: 3D-EWC79627