CAS 1782573-78-7

Fórmula: C19H17Cl3N4O2

InChI: InChI=1S/C19H15ClN4O2.2ClH/c1-10-11(4-3-6-22-10)19(25)24-17-16-13(8-14(20)18(17)26-2)12-5-7-21-9-15(12)23-16;;/h3-9,23H,1-2H3,(H,24,25);2*1H

Chave InChI: AWKOVWFBTRXQLW-UHFFFAOYSA-N

SMILES: CC1=C(C=CC=N1)C(=O)NC2=C3C(=CC(=C2OC)Cl)C4=C(N3)C=NC=C4.Cl.Cl

N-(6-Chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-2-methylnicotinamide dihydrochloride

CAS: 1782573-78-7

N-(6-Chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-2-methylnicotinamide dihydrochloride

Fórmula: C₁₉H₁₇Cl₃N₄O₂

Pureza: >95%

Peso molecular: 439.72

Ref: 54-OR1111458

ML 120B dihydrochloride

CAS: 1782573-78-7

ML 120B dihydrochloride is an ATP-competitive IKKβ inhibitor (IC50 60 nM) reducing multiple myeloma cell growth.

Fórmula: C₁₉H₁₇Cl₃N₄O₂

Cor e Forma: White Solid

Peso molecular: 439.72

Ref: TM-T39199

N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-2-methylnicotinamide dihydrochloride

CAS: 1782573-78-7

Fórmula: C₁₉H₁₇Cl₃N₄O₂

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 439.7229

Ref: IN-DA01LQSC

Ml 120b dihydrochloride

CAS: 1782573-78-7

Ml 120b dihydrochloride (Ml120b) is a small molecule drug that can be used to treat non-alcoholic steatohepatitis. Ml120b inhibits the nuclear factor kappa B (NF-κB) pathway by binding and inhibiting the IκB kinase, which is an enzyme involved in NF-κB activation. Ml120b also has other effects on the liver, such as modulating enzymes involved in lipid metabolism and inflammatory damage. Non-alcoholic fatty liver disease (NAFLD) is characterized by fat accumulation in hepatocytes, inflammation and damage to the liver cells. NAFLD can lead to nonalcoholic steatohepatitis, a more serious form of the disease with inflammation and damage to the liver cells. Diagnostic methods for NAFLD include ultrasound, CT scan and MRI, but these are expensive and not always accurate. As a result, tissue biopsies may be used to diagnose

Fórmula: C₁₉H₁₇Cl₃N₄O₂

Pureza: Min. 95%

Peso molecular: 439.7 g/mol

Ref: 3D-HWC57378