CAS 1799788-94-5

Fórmula: C24H23F4N5O4

InChI: InChI=1S/C24H23F4N5O4/c1-32-12-19(31-13-32)15-9-17(22(29)35)23(30-10-15)36-20-6-7-33(11-18(20)25)21(34)8-14-2-4-16(5-3-14)37-24(26,27)28/h2-5,9-10,12-13,18,20H,6-8,11H2,1H3,(H2,29,35)/t18-,20+/m1/s1

Chave InChI: XJIIVPVOGYFVME-QUCCMNQESA-N

SMILES: CN1C=C(N=C1)C2=CC(=C(N=C2)O[C@H]3CCN(C[C@H]3F)C(=O)CC4=CC=C(C=C4)OC(F)(F)F)C(=O)N

2-[[(3R,4S)-3-Fluoro-1-[2-[4-(trifluoromethoxy)phenyl]acetyl]-4-piperidinyl]oxy]-5-(1-methyl-1H-imidazol-4-yl)-3-pyridinecarboxamide

CAS: 1799788-94-5

2-[[(3R,4S)-3-Fluoro-1-[2-[4-(trifluoromethoxy)phenyl]acetyl]-4-piperidinyl]oxy]-5-(1-methyl-1H-imidazol-4-yl)-3-pyridinecarboxamide

Fórmula: C₂₄H₂₃F₄N₅O₄

Pureza: 99.41%

Peso molecular: 521.46

Ref: 54-PC1030321

2-[[(3R,4S)-3-Fluoro-1-[2-[4-(trifluoromethoxy)phenyl]acetyl]-4-piperidinyl]oxy]-5-(1-methyl-1H-imidazol-4-yl)-3-pyridinecarboxamide

CAS: 1799788-94-5

Pureza: 99.41%

Ref: IN-DA01V4ML

Trk-IN-4

CAS: 1799788-94-5

Trk-IN-4 (PF-6683324) is a potent pan-Trk inhibitor and antinociceptive. It is also a selective type II PTK6 inhibitor antitumor.

Fórmula: C₂₄H₂₃F₄N₅O₄

Pureza: 98.13%

Cor e Forma: White Solid

Peso molecular: 521.4641

Ref: TM-T17169

Trk-in-4

CAS: 1799788-94-5

Trk-in-4 is a small molecule inhibitor, which is synthetically derived to target Trk kinases. These kinases, part of the receptor tyrosine kinase family, are critically involved in neurotrophin signaling pathways, impacting cell differentiation, growth, and survival. Trk-in-4 functions by selectively binding to the ATP-binding site of Trk receptors, thereby blocking downstream signaling cascades.

Fórmula: C₂₄H₂₃F₄N₅O₄

Pureza: Min. 95%

Peso molecular: 521.5 g/mol

Ref: 3D-ZWC78894