CAS 18449-41-7

ácido madasiático

Descrição:

ácido madasiático, com o número CAS 18449-41-7, é um composto triterpenoide de ocorrência natural, derivado principalmente de espécies de plantas do gênero *Madasiaticus*. Este composto é caracterizado por sua complexa estrutura molecular, que tipicamente inclui múltiplos anéis e grupos funcionais, contribuindo para sua atividade biológica. ácido madasiático exibe várias propriedades farmacológicas, incluindo efeitos anti-inflamatórios, antioxidantes e potenciais efeitos anticancerígenos, tornando-o de interesse na química medicinal e na pesquisa de produtos naturais. É frequentemente estudado por seu papel na medicina tradicional e suas potenciais aplicações terapêuticas. O composto é geralmente solúvel em solventes orgânicos, e sua estabilidade pode ser influenciada por fatores ambientais como pH e temperatura. A pesquisa sobre ácido madasiático continua a explorar seus mecanismos de ação e possíveis usos em produtos farmacêuticos, destacando a importância dos produtos naturais na descoberta e desenvolvimento de medicamentos.

Fórmula: C₃₀H₄₈O₆

InChI: InChI=1/C30H48O6/c1-16-9-10-30(25(35)36)12-11-28(5)18(22(30)17(16)2)7-8-21-26(3)13-20(33)24(34)27(4,15-31)23(26)19(32)14-29(21,28)6/h7,16-17,19-24,31-34H,8-15H2,1-6H3,(H,35,36)/t16-,17+,19-,20-,21?,22+,23?,24+,26-,27+,28-,29-,30+/m1/s1

Chave InChI: InChIKey=PRAUVHZJPXOEIF-AOLYGAPISA-N

SMILES: C[C@@]12[C@@]3([C@](C)([C@@]4(C)C(=CC3)[C@]5([C@@](C(O)=O)(CC4)CC[C@@H](C)[C@@H]5C)[H])C[C@@H](O)[C@]1([C@@](CO)(C)[C@@H](O)[C@H](O)C2)[H])[H]

Sinónimos:

• (1S,2R,4aS,6aR,6aS,6bR,8R,8aR,9R,10R,11R,12aR,14bS)-8,10,11-Trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid
• (2Alpha,3Beta,5Xi,6Beta,9Xi)-2,3,6,23-Tetrahydroxyurs-12-En-28-Oic Acid
• (2Alpha,3Beta,6Beta)-2,3,6,23-Tetrahydroxyurs-12-En-28-Oic Acid
• (2α,3β,4α,6β)-2,3,6,23-Tetrahydroxyurs-12-en-28-oic acid
• 2,3,6,23-Tetrahydroxyurs-12-En-28-Oic Acid
• 2α,3β,6β,23-Tetrahydroxy-urs-12-en-28-oic acid
• 6β-Hydroxyasiatic acid
• Brahmic acid
• Cid 12073158
• Madecassic acid
• Nsc 88135
• Urs-12-en-28-oic acid, 2,3,6,23-tetrahydroxy-, (2alpha,3beta,4alpha,6beta)-
• Urs-12-en-28-oic acid, 2,3,6,23-tetrahydroxy-, (2α,3β,4α,6β)-
• Urs-12-en-28-oic acid, 2α,3β,6β,23-tetrahydroxy-
• Hydroxy asiaticoside
• 6-Hydroxyasiatic acid
• 6BETA-HYDROXYASIATIC ACID
• Madecassic acid, froM Centella asiatica
• Madecassic Acid (97%)
• (1S,2R,4aS,6aS,6bR,8R,9R,10R,11R,12aR)-8,10,11-trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid
• (2alpha,3beta,4alpha,6beta)-2,3,6,23-tetrahydroxy-urs-12-en-28-oic acid
• (1S,2R,4aS,6aS,6aS,6bR,8R,8aR,9R,10R,11R,12aR,14bR)-8,10,11-trihydroxy -9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,1 1,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid
• Madecassic acid, 98%, from Centella asiatica (L.) Urb.
• MADECASSIC ACID(P)
• Urs-12-en-28-oic acid, 2,3,6,23-tetrahydroxy-, (2.alpha.,3.beta.,4.alpha.,6.beta.)-
• Brahmic acid 18449-41-7
• 2α,3β,6β,23-Tetrahydroxyurs-12-en-28-oic acid

Urs-​12-​en-​28-​oic acid, 2,​3,​6,​23-​tetrahydroxy-​, (2α,​3β,​4α,​6β)​-

CAS: 18449-41-7

Fórmula: C₃₀H₄₈O₆

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 504.6985

Ref: IN-DA00I1H4

Madecassic acid

CAS: 18449-41-7

Madecassic acid

Pureza: ≥98%

Peso molecular: 504.7g/mol

Ref: 54-BUP10594

Madecassic acid

CAS: 18449-41-7

Fórmula: C₁₄H₁₁ClN₂O

Pureza: ≥ 98.0%

Cor e Forma: White to light pink solid

Peso molecular: 258.70

Ref: 7W-GP1826

Madecassic Acid

CAS: 18449-41-7

Fórmula: C₃₀H₄₈O₆

Peso molecular: 504.71

Ref: 4Z-M-276002

Madecassic acid

CAS: 18449-41-7

Fórmula: C₃₀H₄₈O₆

Pureza: 95%~99%

Peso molecular: 504.708

Ref: BP-BP0910

Madecassic acid

CAS: 18449-41-7

Madecassic acid (L-fucopyranose) is extracted from the whole herb of Centella asiatica.

Fórmula: C₃₀H₄₈O₆

Pureza: 98.80% - 99.69%

Cor e Forma: Solid

Peso molecular: 504.70

Ref: TM-T2758

Madecassic acid

CAS: 18449-41-7

Carboxylic acid with alcohol function

Fórmula: C₃₀H₄₈O₆

Pureza: ≥ 90.0 % (HPLC)

Cor e Forma: Powder

Peso molecular: 504.71

Ref: 5G-80229

Madecassic Acid

Produto Controlado

CAS: 18449-41-7

Applications Madecassic Acid is a terpenoid with an ursane skeleton isolated from Centella asiatica. Madecassic Acid displays anti-inflammatory properties as a result of iNOS, COX-2, TNF-alpha, IL-1beta, and IL-6 inhibition via the downregulation of NF-kappaB activation in RAW 264.7 macrophage cells. Madecassic Acid is found in cosmetic products due to its skin-protective activities.
References Wonh, J.H. et al.: Planta Med., 76, 251 (2010); Kwon, M.C. et al.: J. Biotechnol., 157, 100 (2012); Loiseau, A. et al.: Cosm. Toil., 115, 63 (2000);

Fórmula: C₃₀H₄₈O₆

Pureza: 97%

Cor e Forma: Neat

Peso molecular: 504.70

Ref: TR-M107500

Madecassic acid

Produto Controlado

CAS: 18449-41-7

Madecassic acid is a triterpenoid compound, which is a natural chemical constituent of Centella asiatica, commonly known as Gotu Kola. This source is a perennial herbaceous plant belonging to the Apiaceae family, widely distributed in tropical and subtropical countries. Madecassic acid acts primarily through its anti-inflammatory and antioxidant mechanisms. It modulates inflammatory responses by inhibiting the activation of NF-κB signaling pathways and reducing the production of pro-inflammatory cytokines. Additionally, it contributes to cellular protection by scavenging reactive oxygen species.

Fórmula: C₃₀H₄₈O₆

Pureza: Min. 95%

Peso molecular: 504.7 g/mol

Ref: 3D-FM73960