CAS 18449-41-7
:ácido madasiático
Descrição:
ácido madasiático, com o número CAS 18449-41-7, é um composto triterpenoide de ocorrência natural, derivado principalmente de espécies de plantas do gênero *Madasiaticus*. Este composto é caracterizado por sua complexa estrutura molecular, que tipicamente inclui múltiplos anéis e grupos funcionais, contribuindo para sua atividade biológica. ácido madasiático exibe várias propriedades farmacológicas, incluindo efeitos anti-inflamatórios, antioxidantes e potenciais efeitos anticancerígenos, tornando-o de interesse na química medicinal e na pesquisa de produtos naturais. É frequentemente estudado por seu papel na medicina tradicional e suas potenciais aplicações terapêuticas. O composto é geralmente solúvel em solventes orgânicos, e sua estabilidade pode ser influenciada por fatores ambientais como pH e temperatura. A pesquisa sobre ácido madasiático continua a explorar seus mecanismos de ação e possíveis usos em produtos farmacêuticos, destacando a importância dos produtos naturais na descoberta e desenvolvimento de medicamentos.
Fórmula:C30H48O6
InChI:InChI=1/C30H48O6/c1-16-9-10-30(25(35)36)12-11-28(5)18(22(30)17(16)2)7-8-21-26(3)13-20(33)24(34)27(4,15-31)23(26)19(32)14-29(21,28)6/h7,16-17,19-24,31-34H,8-15H2,1-6H3,(H,35,36)/t16-,17+,19-,20-,21?,22+,23?,24+,26-,27+,28-,29-,30+/m1/s1
Chave InChI:InChIKey=PRAUVHZJPXOEIF-AOLYGAPISA-N
SMILES:C[C@@]12[C@@]3([C@](C)([C@@]4(C)C(=CC3)[C@]5([C@@](C(O)=O)(CC4)CC[C@@H](C)[C@@H]5C)[H])C[C@@H](O)[C@]1([C@@](CO)(C)[C@@H](O)[C@H](O)C2)[H])[H]
Sinónimos:- (1S,2R,4aS,6aR,6aS,6bR,8R,8aR,9R,10R,11R,12aR,14bS)-8,10,11-Trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid
- (2Alpha,3Beta,5Xi,6Beta,9Xi)-2,3,6,23-Tetrahydroxyurs-12-En-28-Oic Acid
- (2Alpha,3Beta,6Beta)-2,3,6,23-Tetrahydroxyurs-12-En-28-Oic Acid
- (2α,3β,4α,6β)-2,3,6,23-Tetrahydroxyurs-12-en-28-oic acid
- 2,3,6,23-Tetrahydroxyurs-12-En-28-Oic Acid
- 2α,3β,6β,23-Tetrahydroxy-urs-12-en-28-oic acid
- 6β-Hydroxyasiatic acid
- Brahmic acid
- Cid 12073158
- Madecassic acid
- Nsc 88135
- Urs-12-en-28-oic acid, 2,3,6,23-tetrahydroxy-, (2alpha,3beta,4alpha,6beta)-
- Urs-12-en-28-oic acid, 2,3,6,23-tetrahydroxy-, (2α,3β,4α,6β)-
- Urs-12-en-28-oic acid, 2α,3β,6β,23-tetrahydroxy-
- Hydroxy asiaticoside
- 6-Hydroxyasiatic acid
- 6BETA-HYDROXYASIATIC ACID
- Madecassic acid, froM Centella asiatica
- Madecassic Acid (97%)
- (1S,2R,4aS,6aS,6bR,8R,9R,10R,11R,12aR)-8,10,11-trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid
- (2alpha,3beta,4alpha,6beta)-2,3,6,23-tetrahydroxy-urs-12-en-28-oic acid
- (1S,2R,4aS,6aS,6aS,6bR,8R,8aR,9R,10R,11R,12aR,14bR)-8,10,11-trihydroxy -9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,1 1,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid
- Madecassic acid, 98%, from Centella asiatica (L.) Urb.
- MADECASSIC ACID(P)
- Urs-12-en-28-oic acid, 2,3,6,23-tetrahydroxy-, (2.alpha.,3.beta.,4.alpha.,6.beta.)-
- Brahmic acid 18449-41-7
- 2α,3β,6β,23-Tetrahydroxyurs-12-en-28-oic acid
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(1S,2R,4aS,6aS,6bR,8R,8aR,9R,10R,11R,12aR,12bR,14bS)-8,10,11-Trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid
CAS:(1S,2R,4aS,6aS,6bR,8R,8aR,9R,10R,11R,12aR,12bR,14bS)-8,10,11-Trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acidPureza:98%Peso molecular:504.7080078Madecassic acid
CAS:Fórmula:C14H11ClN2OPureza:≥ 98.0%Cor e Forma:White to light pink solidPeso molecular:258.70Madecassic acid (Standard)
CAS:Madecassic acid (Standard) is a reference standard for research and analysis in studies involving Madecassic acid. Madecassic acid (L-fucopyranose) is extracted from the whole herb of Centella asiatica.Fórmula:C30H48O6Peso molecular:504.70Urs-12-en-28-oic acid, 2,3,6,23-tetrahydroxy-, (2α,3β,4α,6β)-
CAS:Fórmula:C30H48O6Pureza:98%Cor e Forma:SolidPeso molecular:504.6985Madecassic Acid
CAS:Produto ControladoApplications Madecassic Acid is a terpenoid with an ursane skeleton isolated from Centella asiatica. Madecassic Acid displays anti-inflammatory properties as a result of iNOS, COX-2, TNF-alpha, IL-1beta, and IL-6 inhibition via the downregulation of NF-kappaB activation in RAW 264.7 macrophage cells. Madecassic Acid is found in cosmetic products due to its skin-protective activities.
References Wonh, J.H. et al.: Planta Med., 76, 251 (2010); Kwon, M.C. et al.: J. Biotechnol., 157, 100 (2012); Loiseau, A. et al.: Cosm. Toil., 115, 63 (2000);Fórmula:C30H48O6Pureza:97%Cor e Forma:NeatPeso molecular:504.7(1S,2R,4aS,6aS,6bR,8R,8aR,9R,10R,11R,12aR,12bR,14bS)-8,10,11-Trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid
CAS:(1S,2R,4aS,6aS,6bR,8R,8aR,9R,10R,11R,12aR,12bR,14bS)-8,10,11-Trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acidFórmula:C30H48O6Pureza:98%Peso molecular:504.7Madecassic acid
CAS:Madecassic acid (L-fucopyranose) is extracted from the whole herb of Centella asiatica.Fórmula:C30H48O6Pureza:98.80% - 99.69%Cor e Forma:SolidPeso molecular:504.70Madecassic acid
CAS:Carboxylic acid with alcohol functionFórmula:C30H48O6Pureza:≥ 90.0 % (HPLC)Cor e Forma:PowderPeso molecular:504.71Madecassic acid
CAS:Produto ControladoMadecassic acid is a triterpenoid compound, which is a natural chemical constituent of Centella asiatica, commonly known as Gotu Kola. This source is a perennial herbaceous plant belonging to the Apiaceae family, widely distributed in tropical and subtropical countries. Madecassic acid acts primarily through its anti-inflammatory and antioxidant mechanisms. It modulates inflammatory responses by inhibiting the activation of NF-κB signaling pathways and reducing the production of pro-inflammatory cytokines. Additionally, it contributes to cellular protection by scavenging reactive oxygen species.
Fórmula:C30H48O6Pureza:Min. 95%Peso molecular:504.7 g/mol
