CAS 1858276-04-6

Fórmula: C25H28ClN5O5S2

InChI: InChI=1S/C25H28ClN5O5S2/c1-13-18(23-19-7-16(26)3-2-14(19)4-5-29-23)9-22(37-13)24(33)20-10-28-12-30-25(20)31-17-6-15(21(32)8-17)11-36-38(27,34)35/h2-3,7,9-10,12,15,17,21,23,29,32H,4-6,8,11H2,1H3,(H2,27,34,35)(H,28,30,31)/t15-,17-,21+,23+/m1/s1

Chave InChI: LXRZVMYMQHNYJB-UNXOBOICSA-N

SMILES: CC1=C(C=C(S1)C(=O)C2=CN=CN=C2N[C@@H]3C[C@@H]([C@H](C3)O)COS(=O)(=O)N)[C@H]4C5=C(CCN4)C=CC(=C5)Cl

Subasumstat

CAS: 1858276-04-6

Subasumstat

Fórmula: C₂₅H₂₈ClN₅O₅S₂

Pureza: ≥95%

Cor e Forma: Solid

Peso molecular: 578.1

Ref: 54-BUP04789

Subasumstat

CAS: 1858276-04-6

((1R,2S,4R)-4-((5-(4-((R)-7-Chloro-1,2,3,4-tetrahydroisoquinolin-1-yl)-5-methylthiophene-2-carbonyl)pyrimidin-4-yl)amino)-2-hydroxycyclopentyl)methyl sulfamate

Fórmula: C₂₅H₂₈ClN₅O₅S₂

Pureza: 98%

Peso molecular: 578.1

Ref: IN-DG01093970

Subasumstat

CAS: 1858276-04-6

Subasumstat (TAK-981) is a selective the SUMOylation enzymatic cascade inhibitor, has potential immune-activating and antineoplastic activities.

Fórmula: C₂₅H₂₈ClN₅O₅S₂

Pureza: 97.05% - 98.22%

Cor e Forma: Yellow Solid

Peso molecular: 578.103

Ref: TM-T8428

TAK-981

Produto Controlado

CAS: 1858276-04-6

Fórmula: C₂₅H₂₈ClN₅O₅S₂

Cor e Forma: Neat

Peso molecular: 578.103

Ref: TR-C351340

TAK-981

CAS: 1858276-04-6

TAK-981 is a monoclonal antibody that binds to the lysine residues on the surface of tumor cells. It has been shown to have immunomodulatory effects and induce an antitumor response in vivo. TAK-981 has been shown to increase ATP levels, which may be due to its ability to inhibit the activity of CDK2 and CDK4, thereby preventing cell growth. The monoclonal antibody also inhibits transcriptional regulation by binding to DNA at specific locations and inhibiting RNA polymerase II, which prevents transcription of DNA into RNA. This drug also has pharmacokinetic properties that are effective in mice and humans with cancer.

Fórmula: C₂₅H₂₈ClN₅O₅S₂

Pureza: Min. 95%

Peso molecular: 578.1 g/mol

Ref: 3D-IZC27604