CAS 1883730-99-1

LMP517

Fórmula: C₂₂H₁₉FN₂O₅

InChI: InChI=1S/C22H19FN2O5/c23-12-2-3-13-16(8-12)22(28)25(6-1-4-24-5-7-26)20-14-9-17-18(30-11-29-17)10-15(14)21(27)19(13)20/h2-3,8-10,24,26H,1,4-7,11H2

Chave InChI: YFHMWOJCGJARKT-UHFFFAOYSA-N

SMILES: C1OC2=C(O1)C=C3C(=C2)C4=C(C3=O)C5=C(C=C(C=C5)F)C(=O)N4CCCNCCO

Sinónimos:

• LMP517

LMP517

CAS: 1883730-99-1

LMP517 (NSC 781517), an indenoisoquinoline, is a potent dual TOP1 and TOP2 inhibitor that shows better antitumor activity than its parent compound LMP744 against H82 (Small Cell Lung Cancer) xenografts, inducing TOP1 cleavage complexes (TOP1ccs) and TOP2ccs [1].

Fórmula: C₂₂H₁₉FN₂O₅

Cor e Forma: Solid

Peso molecular: 410.4

Ref: TM-T86817