CAS 188645-44-5

Fórmula: C33H32N2O2

InChI: InChI=1S/C33H32N2O2/c1-32(2)16-17-33(3,4)26-19-28-27(18-25(26)32)34-29(21-10-12-22(13-11-21)31(36)37)24-15-14-20-8-6-7-9-23(20)30(24)35(28)5/h6-15,18-19H,16-17H2,1-5H3,(H,36,37)

Chave InChI: WJVKVKNDLOYKSA-UHFFFAOYSA-N

SMILES: CC1(CCC(C2=CC3=C(C=C21)N=C(C4=C(N3C)C5=CC=CC=C5C=C4)C6=CC=C(C=C6)C(=O)O)(C)C)C

LE-540

CAS: 188645-44-5

LE-540 is a selective retinoic acid receptor β (RARβ) antagonist with a Ki value of 0.22 μM. It shows potential for use in cancer research, particularly in studies focusing on breast and lung cancer.

Fórmula: C₃₃H₃₂N₂O₂

Peso molecular: 488.63

Ref: TM-T213143