CAS 1918143-53-9

Fórmula: C28H21F4NO7

InChI: InChI=1S/C28H21F4NO7/c29-26(30)37-17-6-7-18-19(13-21(38-22(18)12-17)14-1-3-15(4-2-14)24(34)35)33-25(36)27(9-10-27)16-5-8-20-23(11-16)40-28(31,32)39-20/h1-8,11-12,19,21,26H,9-10,13H2,(H,33,36)(H,34,35)/t19-,21-/m1/s1

Chave InChI: QVDYQHXNAQHIKH-TZIWHRDSSA-N

SMILES: C1CC1(C2=CC3=C(C=C2)OC(O3)(F)F)C(=O)N[C@@H]4C[C@@H](OC5=C4C=CC(=C5)OC(F)F)C6=CC=C(C=C6)C(=O)O

4-((2R,4R)-4-(1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)cyclopropane-1-carboxamido)-7-(difluoromethoxy)chroman-2-yl)benzoic acid

CAS: 1918143-53-9

4-((2R,4R)-4-(1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)cyclopropane-1-carboxamido)-7-(difluoromethoxy)chroman-2-yl)benzoic acid

Fórmula: C₂₈H₂₁F₄NO₇

Pureza: 98%

Peso molecular: 559.47

Ref: 54-PC1006486

Galicaftor (ABBV-2222)

CAS: 1918143-53-9

Pureza: 98%

Ref: IN-DA01WTBT

Galicaftor

CAS: 1918143-53-9

4-((2R,4R)-4-(1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)cyclopropane-1-carboxamido)-7-(difluoromethoxy)chroman-2-yl)benzoic acid

Fórmula: C₂₈H₂₁F₄NO₇

Pureza: 98%

Peso molecular: 559.46

Ref: IN-DG01170477

Galicaftor

CAS: 1918143-53-9

Galicaftor is a potent and selective inhibitor of the CFTR protein, which regulates the flow of ions across cell membranes. It binds to the CFTR protein by blocking its chloride channel. This inhibition results in increased fluid secretion in the airways, which may be helpful for patients with cystic fibrosis. Galicaftor also has been shown to inhibit other ion channels including nicotinic acetylcholine receptors and glutamate receptors. Galicaftor is an antibody that can be used as a research tool or diagnostic reagent for cell biology and immunology research, as well as to detect the presence of specific proteins in cells or tissues.

Fórmula: C₂₈H₂₁F₄NO₇

Pureza: Min. 95%

Peso molecular: 559.5 g/mol

Ref: 3D-TBD14353

Galicaftor

CAS: 1918143-53-9

ABBV-2222 is a CFTR corrector which is studied for the treatment of cystic fibrosis (CF).

Fórmula: C₂₈H₂₁F₄NO₇

Pureza: 98.84%

Cor e Forma: Yellow Solid

Peso molecular: 559.4625

Ref: TM-T22252