CAS 2041073-22-5

GNF4877

CAS: 2041073-22-5

(R)-1-(3-(3-Amino-6-(2-fluoro-5-isopropoxyphenyl)pyrazine-2-carboxamido)pyridin-4-yl)piperidine-3-carboxylic acid

Fórmula: C₂₅H₂₇FN₆O₄

Pureza: 99%

Peso molecular: 494.52

Ref: IN-DG01095077

GNF4877

CAS: 2041073-22-5

Fórmula: C₂₅H₂₇FN₆O₄

Pureza: 99%

Peso molecular: 494.5181

Ref: IN-DA01N18O

GNF4877

CAS: 2041073-22-5

GNF4877

Fórmula: C₂₅H₂₇FN₆O₄

Pureza: ≥98%

Peso molecular: 494.52

Ref: 54-BUP05325

GNF4877

CAS: 2041073-22-5

GNF4877 inhibits DYRK1A/GSK3β (IC50: 6/16 nM), blocks NFATc export, and boosts β-cell growth.

Fórmula: C₂₅H₂₇FN₆O₄

Pureza: 98.68% - 99.40%

Cor e Forma: Solid

Peso molecular: 494.52

Ref: TM-T11447

GNF4877

CAS: 2041073-22-5

GNF4877 is an oral medication that has been shown to enhance the ability of insulin-producing cells, called β-cells, to produce and release insulin in response to glucose levels. This drug selectively inhibits the kinase activity of a growth factor receptor called "growth factor receptor β" (GRβ), which is found on the surface of cells. The inhibition of GRβ leads to increased production of a protein called "effector protein 1" (E1P1) in pancreatic β-cells. Increased E1P1 enhances glucose uptake and stimulates the production and release of insulin by β-cells, which can be used as an alternative treatment for diabetes mellitus type 2.

Fórmula: C₂₅H₂₇FN₆O₄

Pureza: Min. 95%

Peso molecular: 494.5 g/mol

Ref: 3D-RGD07322