CAS 205640-91-1

Orexina B (humana)

Descrição:

A orexina B, também conhecida como hipocretina-2, é um neuropeptídeo que desempenha um papel crucial na regulação da excitação, vigília e apetite em humanos. É produzida no hipotálamo e faz parte do sistema de orexina, que inclui orexina A e orexina B. A orexina B é caracterizada por sua sequência e estrutura específica de aminoácidos, que lhe permite se ligar aos receptores de orexina (OX1R e OX2R) no cérebro, influenciando vários processos fisiológicos. Este peptídeo está envolvido na modulação do equilíbrio energético e tem sido implicado em distúrbios do sono, particularmente a narcolepsia. A atividade biológica da orexina B é influenciada por sua estabilidade e interações com outros neuropeptídeos e neurotransmissores. O número CAS 205640-91-1 identifica de forma única este composto, facilitando seu reconhecimento na literatura científica e bancos de dados. No geral, a orexina B é um jogador significativo na neurobiologia, com potenciais implicações para intervenções terapêuticas em distúrbios relacionados ao sono e metabólicos.

Fórmula: C₁₂₃H₂₁₂N₄₄O₃₅S

Sinónimos:

• L-Methioninamide,L-arginyl-L-serylglycyl-L-prolyl-L-prolylglycyl-L-leucyl-L-glutaminylglycyl-L-arginyl-L-leucyl-L-glutaminyl-L-arginyl-L-leucyl-L-leucyl-L-glutaminyl-L-alanyl-L-serylglycyl-L-asparaginyl-L-histidyl-L-alanyl-L-alanylglycyl-L-isoleucyl-L-leu
• H-Arg-Ser-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Ala-Ser-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2
• Orexin B(human)
• Hypocretin-2 (huMan)
• L-Methioninamide, L-arginyl-L-serylglycyl-L-prolyl-L-prolylglycyl-L-leucyl-L-glutaminylglycyl-L-arginyl-L-leucyl-L-glutaminyl-L-arginyl-L-leucyl-L-leucyl-L-glutaminyl-L-alanyl-L-serylglycyl-L-asparaginyl-L-histidyl-L-alanyl-L-alanylglycyl-L-isoleucyl-L-leucyl-L-threonyl-
• Orexin B (human), ≥98% (HPLC)
• REF DUPL: Arg-Ser-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Ala-Ser-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2
• Orexin B (human) (trifluoroacetate salt)
• OREXIN B HUMAN ≥98%
• RSGPPGLQGRLQRLLQASGNHAAGILTM-NH2
• OREXIN B (HUMAN) USP/EP/BP
• HYPOCRETIN-2, HUMAN
• PubChem ID: 90479794
• OREXINS OREXIN B HUMAN
• Human orexin B
• ARG-SER-GLY-PRO-PRO-GLY-LEU-GLN-GLY-ARG-LEU-GLN-ARG-LEU-LEU-GLN-ALA-SER-GLY-ASN-HIS-ALA-ALA-GLY-ILE-LEU-THR-MET-NH2

Orexin B (human)

CAS: 205640-91-1

Like orexin A, orexin B (OXB) is a hypothalamic neuropeptide regulating the feeding behavior. Central administration of OXB to rats stimulated food consumption in a similar manner to orexin A, but the effect did not last as long as that of orexin A. The affinity of orexin B for the OX₁ receptor is significantly lower (IC₅₀ = 240 nM) than that of orexin A. Binding affinities for the OX₂ receptor are similar for orexin A and B (IC₅₀ = 38 nM and 36 nM, respectively, for displacement of radiolabeled orexin A bound to the receptor).

Fórmula: C₁₂₃H₂₁₂N₄₄O₃₅S

Pureza: 96.3%

Cor e Forma: White

Peso molecular: 2899.38

Ref: 01-4028263

Orexin B, human

CAS: 205640-91-1

Orexin B, human agonizes Orexin receptors (OX1 Ki=420 nM, OX2 Ki=36 nM), promotes feeding in rats, and is a neuropeptide.

Fórmula: C₁₂₃H₂₁₂N₄₄O₃₅S

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 2899.34

Ref: TM-TP1139

Orexin B (human)

CAS: 205640-91-1

Orexin B (human)

Ref: 54-BIBA1033

Orexin-B (Human)

CAS: 205640-91-1

Orexin B, also known as hypocretin-2, is a neuropeptide that is produced by a small group of neurons in the hypothalamus, a region of the brain that plays a critical role in regulating various physiological functions, including sleep, appetite, and energy balance.
Orexin B plays a role in promoting wakefulness and arousal and studies have shown that disruptions in the orexin system are associated with various sleep disorders, including narcolepsy and insomnia. In addition, orexin B has been shown to be involved in the regulation of appetite and energy metabolism, and is being explored as a potential target for the treatment of obesity and other metabolic disorders. Therefore, orexin B is an important neuropeptide and is an active area of research in neuroscience and medicine. This product is available as a 0.1mg vial

Fórmula: C₁₂₃H₂₁₂N₄₄O₃₅S

Pureza: Min. 95%

Peso molecular: 2,899.3 g/mol

Ref: 3D-POR-4348-S

Orexin B (human) trifluoroacetate salt

CAS: 205640-91-1

Orexin B (human) trifluoroacetate salt H-Arg-Ser-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Leu-Gln-Arg-Leu-Leu-Gln -Ala -Ser -Gly -Asn -His -Ala -Ala -Gly -Ile -Leu -Thr
Met –NH2 trifluoroacetate salt is an amino acid sequence that is found in the human body. It is a polypeptide that regulates arousal, wakefulness, and appetite. Orexin B (human) trifluoroacetate salt H Arg Ser Gly Pro Pro Gly Leu Gln Gly Arg Leu Gln Arg Leu Leu Gln Ala Ser Gly Asn His Ala Ala Gly Ile Leu Thr Met NH2 trifluoroacetate salt promotes apoptosis by binding to c

Fórmula: C₁₂₃H₂₁₂N₄₄O₃₅S

Pureza: Min. 95%

Peso molecular: 2,899.34 g/mol

Ref: 3D-FO109202