CAS 2058-46-0

Cloridrato de oxitetraciclina

Descrição:

Cloridrato de oxitetraciclina é um antibiótico de amplo espectro pertencente à classe das tetraciclinas, utilizado principalmente no tratamento de várias infecções bacterianas. É caracterizado pela sua capacidade de inibir a síntese de proteínas nas bactérias, ligando-se à subunidade ribossômica 30S, impedindo assim o crescimento e a reprodução de microrganismos suscetíveis. Este composto é tipicamente apresentado como um pó cristalino amarelo a marrom-amarelado, que é solúvel em água e ligeiramente solúvel em álcool. Sua fórmula molecular é C22H24N2O9·HCl, e possui um peso molecular que reflete sua estrutura complexa, que inclui múltiplos grupos funcionais hidroxila e cetona. Cloridrato de oxitetraciclina é eficaz contra uma ampla gama de bactérias gram-positivas e gram-negativas, bem como alguns protozoários. É comumente utilizado na medicina humana e veterinária, e seu uso está associado a potenciais efeitos colaterais, incluindo distúrbios gastrointestinais e fotossensibilidade. Devido ao risco de resistência a antibióticos, seu uso deve ser cuidadosamente monitorado e guiado por testes de suscetibilidade.

Fórmula: C₂₂H₂₄N₂O₉·ClH

InChI: InChI=1S/C22H24N2O9.ClH/c1-21(32)7-5-4-6-8(25)9(7)15(26)10-12(21)17(28)13-14(24(2)3)16(27)11(20(23)31)19(30)22(13,33)18(10)29;/h4-6,12-14,17,25,27-29,32-33H,1-3H3,(H2,23,31);1H/t12-,13-,14+,17+,21-,22+;/m1./s1

Chave InChI: InChIKey=UBDNTYUBJLXUNN-IFLJXUKPSA-N

SMILES: O[C@@]12[C@@]([C@@H](O)[C@]3(C(=C1O)C(=O)C=4C([C@@]3(C)O)=CC=CC4O)[H])([C@H](N(C)C)C(O)=C(C(N)=O)C2=O)[H].Cl

Sinónimos:

• (2Z,4S,4aR,5S,5aR,6S,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,6,10,11,12a-pentahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione hydrochloride
• (3E,11S)-3-[amino(hydroxy)methylidene]-4a,6,7,11,12-pentahydroxy-N,N,11-trimethyl-2,4,5-trioxo-1,2,3,4,4a,5,11,11a,12,12a-decahydrotetracen-1-aminium chloride
• (4S,4aR,5S,5aR,6S,12aS)-4-(dimethylamino)-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride (1:1)
• (4S-(4Alpha,4Aalpha,5Alpha,5Aalpha,6Beta,12Aalpha))-4-(Dimethylamino)-1,4,4A,5,5A,6,11,12A-Octahydro-3,5,6,10,12,12A-Hexahydroxy-6-Methyl-1,11-Dioxo-2-Naphthacenecarboxamide Monohydrochloride
• 1-Dimethylamino-1,4,6,11,12,13,14,18-octahydro-2,5,7,11,12,14-hexahydroxy-4,6-dioxo-11-methylnaphthacene-3-carbonamide hydrochloride
• 10,12,12A-Hexahydroxy-6-Methyl-1,11-Dioxo-Monohydrochloride
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-, hydrochloride (1:1), (4S,4aR,5S,5aR,6S,12aS)-
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-, monohydrochloride
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, (4S,4aR,5S,5aR,6S,12aS)-
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, [4S-(4α,4aα,5α,5aα,6β,12aα)]-
• 5-Hydroxytetracycline Hydrochloride
• 5-Hydroxytetracycline monohydrochloride
• Alamycin
• Aquacycline
• Biocyl
• Duphacycline
• Engemycin
• Gynamousse
• Liquamycin Injectable
• Maxicyklin
• Mepatar
• Occrycetin
• Otc Hcl
• Oxlopar
• Oxy WS
• Oxy-Dumocyclin
• Oxybiocycline
• Oxybiotic
• Oxycyclin
• Oxyject
• Oxylag
• Oxypan
• Oxytertracycline HCL
• Oxytet
• Oxytetracid
• Oxytetracycline Hydrochloride
• Oxytetrin
• Teramycin
• Terraject
• Terramycin 343
• Terramycin hydrochloride
• Tetra-Tabilinen
• Tetramel
• Tetran hydrochloride
• Toxinal
• Vetilmicin

Oxytetracycline Hydrochloride

CAS: 2058-46-0, 6153-64-6, 79-57-2

Fórmula: C₂₂H₂₄N₂O₉·HCl

Pureza: >95.0%(T)(HPLC)

Cor e Forma: Light orange to Yellow to Green powder to crystal

Peso molecular: 496.90

Ref: 3B-O0475

Oxytetracycline hydrochloride

CAS: 2058-46-0

Impairs mitochondrial protein synthesis

Fórmula: C₂₂H₂₅ClN₂O₉

Cor e Forma: Yellow, Powder or crystals or crystalline powder

Peso molecular: 496.90

Ref: 02-J62489

Oxytetracycline Hydrochloride

CAS: 2058-46-0

Cor e Forma: Neat

Ref: 61-FOR0554.00

Oxytetracycline hydrochloride

CAS: 2058-46-0

Oxytetracycline hydrochloride

Cor e Forma: Yellow

Ref: 47-275

OXYTETRACYCLINE HYDROCHLORIDE CRS

CAS: 2058-46-0

OXYTETRACYCLINE HYDROCHLORIDE CRS

Fórmula: C₂₂H₂₆Cl₂N₂O₉

Cor e Forma: Crystalline Powder. Yellow. Powder.

Peso molecular: 533.3558

Ref: 41-O0500000

Oxytetracycline Hydrochloride

CAS: 2058-46-0

Lactams, nesoi

Fórmula: C₂₂H₂₄N₂O₉·HCl

Cor e Forma: Yellow Powder

Peso molecular: 460.14818

Ref: 45-1491015

Oxytetracycline hydrochloride

CAS: 2058-46-0

Fórmula: C₂₂H₂₅ClN₂O₉

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 496.8949

Ref: IN-DA0035YD

Oxytetracycline hydrochloride

CAS: 2058-46-0

Oxytetracycline hydrochloride

Pureza: 97%

Peso molecular: 496.89g/mol

Ref: 54-BIO0140

Oxytetracycline HCl

CAS: 2058-46-0

Fórmula: C₂₂H₂₄N₂O₉·HCl

Cor e Forma: White To Off-White Solid

Peso molecular: 460.44 36.46

Ref: 4Z-O-164

Oxytetracycline Hydrochloride

CAS: 2058-46-0

Oxytetracycline Hydrochloride

Pureza: ≥95%

Peso molecular: 496.89g/mol

Ref: 54-BUP17079

Oxytetracycline hydrochloride

CAS: 2058-46-0

Fórmula: C₂₂H₂₄N₂O₉·HCl

Pureza: 95.0 - 102.0 % (anhydrous basis)

Cor e Forma: Yellow crystalline powder

Peso molecular: 496.90

Ref: 7W-GA3147

PharmaVetResiMix 5 Tetracyclines-v10 10 µg/mL in Methanol

Produto Controlado

CAS: 101342-45-4, 14206-58-7, 179471-95-5, 2058-46-0, 23313-80-6, 24390-14-5, 41411-66-9, 64-72-2, 64-73-3, 64-75-5

Cor e Forma: Mixture

Ref: 04-A30000035ME

Oxytetracycline hydrochloride

Produto Controlado

CAS: 2058-46-0

Fórmula: C₂₂H₂₄N₂O₉·ClH

Cor e Forma: Neat

Peso molecular: 496.89

Ref: 04-C15820000

Oxytetracycline Hydrochloride

Produto Controlado

CAS: 2058-46-0

Fórmula: C₂₂H₂₄N₂O₉·ClH

Cor e Forma: Neat

Peso molecular: 496.89

Ref: 86-MM0554.00

Oxytetracycline hydrochloride 100 µg/mL in Acetonitrile

CAS: 2058-46-0

Fórmula: C₂₂H₂₄N₂O₉·ClH

Cor e Forma: Single Solution

Peso molecular: 496.89

Ref: 04-A15820000AL-100

Oxytetracycline-13C-d3 HCl

CAS: 2058-46-0

Fórmula: C₂₁₁₃CH₂₁D₃N₂O₉·HCl

Peso molecular: 464.45 36.46

Ref: 4Z-O-1613

Oxytetracycline Hydrochloride

CAS: 2058-46-0

Dalimycin (Oxytetracycline Hydrochloride), from Streptomyces rimosus, blocks tRNA binding, hindering protein synthesis.

Fórmula: C₂₂H₂₅ClN₂O₉

Pureza: 99.86%

Cor e Forma: Yellow Crystalline Solid

Peso molecular: 496.89

Ref: TM-T21430

Oxytetracycline Hydrochloride

CAS: 2058-46-0

Stability Hygroscopic
Applications Antibiotic substance isolated from the elaboration products of the actinomycete, Streptomyces rimosus, grown on a suitable medium. Antibacterial.
References Finlay, et al.: Science, 111, 85 (1950), Weiss, et al.: Antibiot. Chemother., 7, 374 (1957), Kruse, H., et al.: Microb. Drug. Resist., 5, 135, (1999), van den Bogaard, A., et al.: J. Antimicrob. Chemother., 45, 663 (2000), Nwosu, V., et al.: Res. Microbiol., 152, 421 (2001),

Fórmula: C₂₂H₂₄N₂O₉·ClH

Cor e Forma: Yellow

Peso molecular: 496.89

Ref: TR-O877500

Oxytetracycline-¹³CD₃ Hydrochloride (>85%)

Produto Controlado

CAS: 2058-46-0

Fórmula: CC₂₁D₃H₂₁N₂O₉·HCl

Pureza: >85%

Cor e Forma: Neat

Peso molecular: 500.906

Ref: TR-O877611

Oxytetracycline hydrochloride

CAS: 2058-46-0

A broad-spectrum antibiotic of tetracycline class which inhibits protein synthesis by targeting the 30S ribosome subunit. It has been used in human medicine as well as in veterinary medicine and agriculture.

Fórmula: C₂₂H₂₄N₂O₉•HCl

Pureza: Min. 95%

Cor e Forma: Yellow Powder

Peso molecular: 496.89 g/mol

Ref: 3D-FO29661