CAS 2101821-86-5

Fórmula: C18H18N8

InChI: InChI=1S/C18H18N8/c1-26-10-15(24-25-26)21-18-22-16-13(8-9-19-16)17(23-18)20-14-7-6-11-4-2-3-5-12(11)14/h2-5,8-10,14H,6-7H2,1H3,(H3,19,20,21,22,23)/t14-/m0/s1

Chave InChI: ZQSBNCTWGKRISE-AWEZNQCLSA-N

SMILES: CN1C=C(N=N1)NC2=NC3=C(C=CN3)C(=N2)N[C@H]4CCC5=CC=CC=C45

LRRK2-IN-17

CAS: 2101821-86-5

LRRK2-IN-17 is an orally active LRRK2 inhibitor with IC50 values of 3.5 nM for WT and 3.3 nM for G2019S, and it also inhibits RET kinase with an IC50 of 59 nM. LRRK2-IN-17 is utilized in research related to cancer and Parkinson's disease (PD).

Fórmula: C₁₈H₁₈N₈

Cor e Forma: Solid

Peso molecular: 346.39

Ref: TM-T207158