CAS 211914-51-1

Dabigatrano

Descrição:

Dabigatrano é um medicamento anticoagulante oral usado principalmente para a prevenção e tratamento de distúrbios tromboembólicos, como fibrilação atrial e trombose venosa profunda. Funciona como um inibidor direto da trombina, o que significa que inibe diretamente a atividade da trombina, uma enzima crucial para a formação de coágulos sanguíneos. A fórmula química de Dabigatrano é C19H21N7O5S, e apresenta uma estrutura única que inclui um grupo ácido carboxílico, um grupo amino e um moiety sulfonamida. Dabigatrano é caracterizado por sua alta biodisponibilidade e rápido início de ação, tornando-o eficaz para o manejo de distúrbios de coagulação. É tipicamente administrado como um pró-fármaco, Dabigatrano etexilato, que é convertido em sua forma ativa no corpo. A substância é conhecida por sua farmacocinética previsível, permitindo dosagem fixa sem a necessidade de monitoramento rotineiro dos níveis de anticoagulação, ao contrário dos anticoagulantes tradicionais, como a varfarina. No entanto, é essencial considerar os potenciais efeitos colaterais, incluindo riscos de sangramento, e usá-lo sob supervisão médica.

Fórmula: C₂₅H₂₅N₇O₃

InChI: InChI=1/C25H25N7O3/c1-31-20-10-7-17(25(35)32(13-11-23(33)34)21-4-2-3-12-28-21)14-19(20)30-22(31)15-29-18-8-5-16(6-9-18)24(26)27/h2-10,12,14,29H,11,13,15H2,1H3,(H3,26,27)(H,33,34)

Chave InChI: InChIKey=YBSJFWOBGCMAKL-UHFFFAOYSA-N

SMILES: CN1C=2C(=CC(C(N(CCC(O)=O)C3=CC=CC=N3)=O)=CC2)N=C1CNC4=CC=C(C(=N)N)C=C4

Sinónimos:

• 3-[[2-[[(4-Carbamimidoylphenyl)Amino]Methyl]-1-Methyl-Benzoimidazole-5-Carbonyl]-Pyridin-2-Yl-Amino]Propanoic Acid
• Bibr 953
• Bibr 953Zw
• Dabigatran
• N-(2-(4-(N-(Hexyloxycarbonyl)Amidino)Phenylaminomethyl)-1-Methyl-1H-Benzimidazol-5-Ylcarbonyl)-N-(2-Pyridyl)-Beta-Alanine Ethyl Ester
• N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanine
• beta-alanine, N-[[2-[[[4-(aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-
• β-Alanine, N-[[2-[[[4-(aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-
• N-[(2-{[(4-carbamimidoylphenyl)amino]methyl}-1-methyl-1H-ben...
• N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-beta-alanine
• Dabiga group
• BIBR953;BIBR 953;BIBR-953
• Dabigatran etexilate impurity1513
• 3-[[2-[[(4-carbaMiMidoylphenyl)aMino]Methyl]-1-Met
• BIBR 953 (Dabigatran, Pradaxa)
• Dabigatran(BIB-953
• Dabigatran Q: What is the CAS Number of
• BIB-953
• 3-(2-((4-carbamimidoylphenylamino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoic acid
• BIBR 953(Dabigatran)
• Dabigatran Etexilate Mesilate
• Dabigatran etexilate-1
• Dabigatran base
• 3-[[2-[[(4-carbaMiMidoylphenyl)aMino]Methyl]-1-Methyl-benzoiMidazole-5-carbonyl]-pyridin-2-yl-aMino]
• 3-[[2-[(4-carbamimidoylanilino)methyl]-1-methylbenzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoic
• Dabigatran3-(2-((4-carbamimidoylphenylamino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoic acid
• Dabigatran Ester Impurity B
• Dabigatran API
• BIBR 953;BIBR 953ZW;BIBR953;BIB-953
• Dabigatran Impurity U
• 3-[[2-[(4-carbamimidoylanilino)methyl]-1-methylbenzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoic acid
• 3-[[2-[(4-carbamimidoylanilino)methyl]-1-methylbenzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoic acid Dabigatran (BIBR 953)
• Dabigatran (Acid)
• ethyl 3-(2-(((4-(N'-((hexan-2-yloxy)carbonyl)carbamimidoyl)phenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate
• N-[[2-[[[4-(AMinoiMinoMethyl)phenyl]aMino]Methyl]-1-Methyl-1H-benzo[d]iMidazol-5-yl]carbonyl]-N-pyridin-2-yl-beta-alanine
• DabigatranQ: What is
• Dabigatran (BIBR 953)
• Dabigatran etexilate impurity189
• Dabigatran Impurity b
• N- (2-{ (4-carbaMiMidoylphenyl)aMino Methyl}-1-Met
• Dabigatran Q: What are the applications of
• Dabigatran Q: What is the storage condition of
• Dabigatran USP/EP/BP
• CS-1864
• N-[(2-{[(4-carbaMiMidoylphenyl)aMino]Methyl}-1-Methyl-1HbenziMidazol-

Dabigatran

CAS: 211914-51-1

Fórmula: C₂₅H₂₅N₇O₃

Pureza: >95.0%(HPLC)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 471.52

Ref: 3B-D5902

3-(2-(((4-Carbamimidoylphenyl)Amino)Methyl)-1-Methyl-N-(Pyridin-2-Yl)-1H-Benzo[D]Imidazole-5-Carboxamido)Propanoic Acid

CAS: 211914-51-1

3-(2-(((4-Carbamimidoylphenyl)Amino)Methyl)-1-Methyl-N-(Pyridin-2-Yl)-1H-Benzo[D]Imidazole-5-Carboxamido)Propanoic Acid

Fórmula: C₂₅H₂₅N₇O₃

Pureza: 98%

Peso molecular: 471.51

Ref: 54-OR1010625

N-Nitroso Dabigatran Etexilate-13C-d3

CAS: 211914-51-1

Fórmula: C₃₃₁₃CH₃₇D₃N₈O₆

Cor e Forma: White To Off-White Solid

Peso molecular: 660.75

Ref: 4Z-D-59138

Dabigatran-13C-d3

CAS: 211914-51-1

Fórmula: C₂₄₁₃CH₂₂D₃N₇O₃

Cor e Forma: White To Off-White Solid

Peso molecular: 475.53

Ref: 4Z-D-59109

Dabigatran

CAS: 211914-51-1

Dabigatran

Fórmula: C₂₅H₂₅N₇O₃

Pureza: ≥95%

Peso molecular: 471.51

Ref: 54-BUP05533

Dabigatran

CAS: 211914-51-1

Fórmula: C₂₅H₂₅N₇O₃

Cor e Forma: White To Off-White Solid

Peso molecular: 471.52

Ref: 4Z-D-591

Dabigatran (Standard)

CAS: 211914-51-1

Dabigatran (Standard) is a reference standard for research and analysis in studies involving Dabigatran. Dabigatran (BIBR 953ZW) is a THROMBIN inhibitor which acts by binding and blocking thrombogenic activity and the prevention of thrombus formation. It is used to reduce the risk of stroke and systemic EMBOLISM in patients with nonvalvular atrial fibrillation.

Fórmula: C₂₅H₂₅N₇O₃

Cor e Forma: Solid

Peso molecular: 471.5111

Ref: TM-TMSM-3464

Dabigatran

CAS: 211914-51-1

Fórmula: C₂₅H₂₅N₇O₃

Cor e Forma: Neat

Peso molecular: 471.51

Ref: 86-MM3522.02

Dabigatran

CAS: 211914-51-1

Fórmula: C₂₅H₂₅N₇O₃

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 471.5111

Ref: IN-DA00I41W

Dabigatran

CAS: 211914-51-1

Applications Nonpeptide, direct thrombin inhibitor. Antithrombotic.
References Hauel, N., et al.: J. Med. Chem., 45, 1757 (2002), Mungall, D., et al.: Curr. Opin. Invest. Drugs, 3, 095 (2002), Stangier, J., et al.: J. Clin. Pharmacol., 45, 555 (2005),

Fórmula: C₂₅H₂₅N₇O₃

Cor e Forma: Neat

Peso molecular: 471.51

Ref: TR-D100090

Dabigatran-d7 (>90%)

Produto Controlado

CAS: 211914-51-1

Applications Dabigatran-d7, is the labeled analogue of Dabigatran (D100090), Nonpeptide, direct thrombin inhibitor. Antithrombotic.
References Hauel, N., et al.: J. Med. Chem., 45, 1757 (2002), Mungall, D., et al.: Curr. Opin. Invest. Drugs, 3, 095 (2002), Stangier, J., et al.: J. Clin. Pharmacol., 45, 555 (2005),

Fórmula: C₂₅H₁₈D₇N₇O₃

Pureza: >90%

Cor e Forma: Neat

Peso molecular: 478.55

Ref: TR-D100093

Dabigatran

CAS: 211914-51-1

Dabigatran (BIBR 953ZW), a thrombin inhibitor, prevents thrombus formation, reducing stroke and embolism risk in nonvalvular atrial fibrillation patients.

Fórmula: C₂₅H₂₅N₇O₃

Pureza: 97.44% - 98.71%

Cor e Forma: Solid

Peso molecular: 471.5111

Ref: TM-T6295

Dabigatran

CAS: 211914-51-1

3-(2-(((4-Carbamimidoylphenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoic acid

Fórmula: C₂₅H₂₅N₇O₃

Pureza: 98%

Peso molecular: 471.51

Ref: IN-DG158683

Dabigatran

CAS: 211914-51-1

Fórmula: C₂₅H₂₅N₇O₃

Peso molecular: 471.51

Ref: ST-EA-CP-D5003

Dabigatran

CAS: 211914-51-1

Fórmula: C₂₅H₂₅N₇O₃

Peso molecular: 471.5

Ref: BE-RMCD001000

Dabigatran

CAS: 211914-51-1

Fórmula: C₂₅H₂₅N₇O₃

Peso molecular: 471.5

Ref: BE-MU-7354

DABIGATRAN

CAS: 211914-51-1

Pureza: 98%

Peso molecular: 471.5209961

Ref: 10-F799805

Dabigatran

CAS: 211914-51-1

Dabigatran is an oral prodrug that is converted to dabigatran etexilate by esterases in the blood. Dabigatran etexilate is an anticoagulant that inhibits thrombin formation and also prevents the conversion of fibrinogen to fibrin. The drug is used for the prevention of stroke or embolism in people with atrial fibrillation, as well as treatment and prevention of deep venous thrombosis and pulmonary embolism. Dabigatran etexilate has a long half-life of 15-20 hours, meaning that it can be administered once daily. There are two analytical methods for measuring dabigatran concentrations in plasma: one based on the activity of the drug's main metabolite (dabigatran etexilate) and another based on both dabigatran and its active metabolite (dabigatran etexil

Fórmula: C₂₅H₂₅N₇O₃

Pureza: Min. 95%

Cor e Forma: White Powder

Peso molecular: 471.51 g/mol

Ref: 3D-FD32710