CAS 21462-39-5

Cloridrato de clindamicina

Descrição:

Cloridrato de clindamicina é um antibiótico pertencente à classe das lincosamidas, utilizado principalmente para tratar várias infecções bacterianas, particularmente aquelas causadas por bactérias anaeróbias e certos protozoários. É eficaz contra infecções de pele, infecções do trato respiratório e alguns tipos de infecções ósseas. A substância aparece como um pó cristalino branco a off-white, que é solúvel em água e metanol, mas tem solubilidade limitada em solventes orgânicos. Sua fórmula química é C18H20ClN2O2S, e tem um peso molecular de aproximadamente 343,88 g/mol. Cloridrato de clindamicina atua inibindo a síntese de proteínas bacterianas, impedindo assim o crescimento e a reprodução das bactérias. Geralmente é administrado por via oral ou intravenosa, dependendo da gravidade da infecção. Os efeitos colaterais podem incluir distúrbios gastrointestinais, como diarreia, e em casos raros, pode levar à diarreia associada ao Clostridium difficile. Devido ao seu mecanismo de ação e espectro de atividade, a clindamicina é uma opção valiosa no tratamento de infecções onde a penicilina é ineficaz ou contraindicada.

Fórmula: C₁₈H₃₄Cl₂N₂O₅S

InChI: InChI=1/C18H33ClN2O5S.ClH/c1-5-6-10-7-11(21(3)8-10)17(25)20-12(9(2)19)16-14(23)13(22)15(24)18(26-16)27-4;/h9-16,18,22-24H,5-8H2,1-4H3,(H,20,25);1H/t9?,10-,11+,12?,13+,14-,15-,16-,18-;/m0./s1

Chave InChI: InChIKey=AUODDLQVRAJAJM-XJQDNNTCSA-N

SMILES: [C@@H](NC(=O)[C@@H]1C[C@@H](CCC)CN1C)([C@H](C)Cl)[C@]2(O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O)[H].Cl

Sinónimos:

• (2R,4S)-N-[2-chloro-1-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methylsulfanyl-tetrahydropyran-2-yl]propyl]-1-methyl-4-propyl-pyrrolidine-2-carboxamide hydrochloride
• 7(S)-Chloro-7-deoxylincomycin hydrochloride
• 7-Chloro-7-deoxylincomycin hydrochloride
• <span class="text-smallcaps">L</smallcap>-threo-α-<smallcap>D</smallcap>-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-4-propyl-<smallcap>L</span>-2-pyrrolidinecarboxamido)-1-thio-, monohydrochloride, trans- α-
• <span class="text-smallcaps">L</smallcap>-threo-α-<smallcap>D</span>-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-, monohydrochloride, (2S-trans)-
• <span class="text-smallcaps">L</smallcap>-threo-α-<smallcap>D</span>-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-, hydrochloride (1:1)
• <span class="text-smallcaps">L</smallcap>-threo-α-<smallcap>D</span>-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-, monohydrochloride
• Antirobe vet.
• Cleocin hydrochloride
• ClidamycinHydrochloride
• Clinacin
• Clindamycin HCl
• Clindavet
• Clindimycin hydrochloride
• Clindomycin hydrochloride
• Dalacina
• methyl 7-chloro-6,7,8-trideoxy-6-({[(2R)-1-methyl-4-propylpyrrolidinium-2-yl]carbonyl}amino)-1-thio-beta-L-erythro-octopyranoside chloride
• methyl 7-chloro-6,7,8-trideoxy-6-{[(4R)-1-methyl-4-propyl-L-prolyl]amino}-1-thio-L-threo-alpha-D-galacto-octopyranoside hydrochloride (1:1)
• L-threo-α-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-, monohydrochloride, (2S-trans)-
• Clindamycin hydrochloride
• L-threo-α-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-, hydrochloride (1:1)
• L-threo-α-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-, monohydrochloride
• L-threo-α-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-, monohydrochloride, trans- α-
• (7S)-7-CHLORO-7-DEOXYLINCOMYCIN HYDROCHLORIDE
• clindomycinhydrochloride
• Lujiemycin
• CLINDAMYCINHYDROCHLORIDE,CRYSTAL
• L-threo-.alpha.-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(2S,4R)-1-methyl-4-propyl-2-pyrrolidinylcarbonylamino-1-thio-, monohydrochloride
• clindimycinhydrochloride
• Clindaymcin Hydrochloride BP98,USP25,EP97
• 7(S)-CHLORO-7-DEOXYLINCOMYCIN HCL
• 7-chloro-7-deoxylincomycinhydrochloride
• monohydrochloride,(2s-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio
• CLEOCIN
• (2S-TRANS)-METHYL 7-CHLORO-6,7,8-TRIDEOXY-6[[(1-METHYL-4-PROPYL-2-PYRROLIDINYL)CARBONYL]AMINO]-1-THIO-L-THREO-ALPHA-D-GALACTO-OCTOPYRANOSIDE
• 7(S)-CHLORO-7-DEOXYLINCOMYCIN
• CLINDAMYCIN HC

Clindamycin Hydrochloride Monohydrate

CAS: 18323-44-9, 21462-39-5, 58207-19-5

Fórmula: C₁₈H₃₃ClN₂O₅S·HCl·H₂O

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 479.46

Ref: 3B-C2256

Clindamycin Hydrochloride

CAS: 21462-39-5

Cor e Forma: Neat

Ref: 61-FOR0259.00

CLINDAMYCIN HYDROCHLORIDE RS

CAS: 21462-39-5

CLINDAMYCIN HYDROCHLORIDE RS

Ref: 41-ICRS46473

CLINDAMYCIN HYDROCHLORIDE CRS

CAS: 21462-39-5

CLINDAMYCIN HYDROCHLORIDE CRS

Fórmula: C₁₈H₃₄Cl₂N₂O₅S

Cor e Forma: Crystalline Powder. White. Powder.

Peso molecular: 461.444

Ref: 41-C2250000

(7S)-7-Chloro-7-deoxylincomycin hydrochloride

CAS: 21462-39-5

Fórmula: C₁₈H₃₄Cl₂N₂O₅S

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 461.4440

Ref: IN-DA003P0L

Clindamycin HCl (Clindamycin Phosphate EP Impurity E HCl)

CAS: 21462-39-5

Fórmula: C₁₈H₃₃ClN₂O₅S·HCl

Cor e Forma: White To Off-White Solid

Peso molecular: 424.99 36.46

Ref: 4Z-C-5071

Clindamycin hydrochloride

CAS: 21462-39-5

Fórmula: C₁₈H₃₃ClN₂O₅S·HCl·xH₂O

Pureza: ≥ 800μg/mg (C18H33ClN2O5S, as is)

Cor e Forma: White to off-white powder

Peso molecular: 461.44 (anhydrous)

Ref: 7W-GA5034

Clindamycin hydrochloride

CAS: 21462-39-5

Clindamycin hydrochloride

Pureza: ≥98%

Peso molecular: 461.44g/mol

Ref: 54-BUP14814

Clindamycin hydrochloride

CAS: 21462-39-5

Clindamycin hydrochloride

Fórmula: C₁₈H₃₃ClN₂O₅S·ClH

Pureza: 94% (q-nmr) (calculated (Typical Value in Batch COA)

Cor e Forma: white powder

Peso molecular: 461.44395g/mol

Ref: 54-BIC0117

Clindamycin Hydrochloride

CAS: 21462-39-5

Cor e Forma: Neat

Ref: 86-MM0259.00

Clindamycin 1000 µg/mL in Acetonitrile

Produto Controlado

CAS: 21462-39-5

Fórmula: C₁₈H₃₃ClN₂O₅S·ClH

Cor e Forma: Single Solution

Peso molecular: 461.44

Ref: 04-A11670090AL-1000

Clindamycin hydrochloride

Produto Controlado

CAS: 21462-39-5

Fórmula: C₁₈H₃₃ClN₂O₅S·ClH

Cor e Forma: Neat

Peso molecular: 461.44

Ref: 04-C11670100

Clindamycin hydrochloride

CAS: 21462-39-5

Clindamycin hydrochloride (Clinimycin HCl) inhibits protein synthesis by acting on the 50S ribosomal. Clindamycin is a chlorinated broad-spectrum antibiotic.

Fórmula: C₁₈H₃₃ClN₂O₅S·HCl

Pureza: 99.80%

Cor e Forma: White Crystalline Powder

Peso molecular: 461.44

Ref: TM-T6448

Clindamycin Hydrochloride

CAS: 21462-39-5

Fórmula: C₁₈H₃₃ClN₂O₅SHCl

Peso molecular: 425.0 : 36.5

Ref: ST-EA-CP-C26021

Clindamycin Hydrochloride

CAS: 21462-39-5

Impurity Clindamycin Phosphate EP Impurity E
Stability Hygroscopic
Applications Clindamycin Hydrochloride (Clindamycin Phosphate EP Impurity E) is a semi-synthetic antibiotic prepared from Lincomycin. Antibacterial.
References Birkenmeyer, R.D., et al.: J. Med. Chem., 13, 616 (1970); Oesterling, et al.: J. Pharm. Sci., 59, 63 (1970); Gray, J.E., et al.: Toxicol. Appl. Pharmacol., 21, 516 (1972); Brown, L.W., et al.: Anal. Profiles Drug Subs., 10, 75 (1981);

Fórmula: C₁₈H₃₃ClN₂O₅S·ClH

Cor e Forma: White To Off-White

Peso molecular: 461.44

Ref: TR-C580000

Clindamycin hydrochloride

CAS: 21462-39-5

Inhibitor of protein synthesis; lincosamide class

Fórmula: C₁₈H₃₄Cl₂N₂O₅S

Cor e Forma: White Powder

Peso molecular: 461.44 g/mol

Ref: 3D-AC07735

Clindamycin hydrochloride - 94%

CAS: 21462-39-5

Clindamycin hydrochloride - 94% is an antibiotic that belongs to the lincosamide class of antibiotics, derived from the bacterium Streptomyces lincolnensis. This compound functions predominantly as a bacterial protein synthesis inhibitor, exerting its effects by binding to the 50S subunit of the bacterial ribosome. This binding action disrupts the process of peptide chain elongation, thereby impeding the growth and proliferation of susceptible bacteria.

Fórmula: C₁₈H₃₃ClN₂O₅S·HCl

Cor e Forma: Powder

Peso molecular: 461.44 g/mol

Ref: 3D-AC178993

Clindamycin (hydrochloride)

CAS: 21462-39-5

Pureza: 98%

Peso molecular: 460.16

Ref: 10-F554440

Cis-Clindamycin Hydrochloride

Produto Controlado

CAS: 21462-39-5

Fórmula: C₁₈H₃₃ClN₂O₅S·ClH

Cor e Forma: Neat

Peso molecular: 460.15655

Ref: TR-C580080