CAS 21462-39-5: Cloridrato de clindamicina

Descrição: Cloridrato de clindamicina é um antibiótico pertencente à classe das lincosamidas, utilizado principalmente para tratar várias infecções bacterianas, particularmente aquelas causadas por bactérias anaeróbias e certos protozoários. É eficaz contra infecções de pele, infecções do trato respiratório e alguns tipos de infecções ósseas. A substância aparece como um pó cristalino branco a off-white, que é solúvel em água e metanol, mas tem solubilidade limitada em solventes orgânicos. Sua fórmula química é C18H20ClN2O2S, e tem um peso molecular de aproximadamente 343,88 g/mol. Cloridrato de clindamicina atua inibindo a síntese de proteínas bacterianas, impedindo assim o crescimento e a reprodução das bactérias. Geralmente é administrado por via oral ou intravenosa, dependendo da gravidade da infecção. Os efeitos colaterais podem incluir distúrbios gastrointestinais, como diarreia, e em casos raros, pode levar à diarreia associada ao Clostridium difficile. Devido ao seu mecanismo de ação e espectro de atividade, a clindamicina é uma opção valiosa no tratamento de infecções onde a penicilina é ineficaz ou contraindicada.

Fórmula: C₁₈H₃₃ClN₂O₅S·ClH

InChI: InChI=1S/C18H33ClN2O5S.ClH/c1-5-6-10-7-11(21(3)8-10)17(25)20-12(9(2)19)16-14(23)13(22)15(24)18(26-16)27-4;/h9-16,18,22-24H,5-8H2,1-4H3,(H,20,25);1H/t9-,10+,11-,12+,13-,14+,15+,16+,18+;/m0./s1

Chave InChI: InChIKey=AUODDLQVRAJAJM-XJQDNNTCSA-N

SMILES: Cl.O=C(NC(C(Cl)C)C1OC(SC)C(O)C(O)C1O)C2N(C)CC(CCC)C2

Sinónimos:

• (2R,4S)-N-[2-chloro-1-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methylsulfanyl-tetrahydropyran-2-yl]propyl]-1-methyl-4-propyl-pyrrolidine-2-carboxamide hydrochloride
• 7(S)-Chloro-7-deoxylincomycin hydrochloride
• 7-Chloro-7-deoxylincomycin hydrochloride
• <span class="text-smallcaps">L</smallcap>-threo-α-<smallcap>D</smallcap>-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-4-propyl-<smallcap>L</span>-2-pyrrolidinecarboxamido)-1-thio-, monohydrochloride, trans- α-
• <span class="text-smallcaps">L</smallcap>-threo-α-<smallcap>D</span>-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-, monohydrochloride, (2S-trans)-
• <span class="text-smallcaps">L</smallcap>-threo-α-<smallcap>D</span>-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-, hydrochloride (1:1)
• <span class="text-smallcaps">L</smallcap>-threo-α-<smallcap>D</span>-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-, monohydrochloride
• Antirobe vet.
• Cleocin hydrochloride
• ClidamycinHydrochloride
• Clinacin
• Clindamycin HCl
• Clindavet
• Clindimycin hydrochloride
• Clindomycin hydrochloride
• Dalacina
• methyl 7-chloro-6,7,8-trideoxy-6-({[(2R)-1-methyl-4-propylpyrrolidinium-2-yl]carbonyl}amino)-1-thio-beta-L-erythro-octopyranoside chloride
• methyl 7-chloro-6,7,8-trideoxy-6-{[(4R)-1-methyl-4-propyl-L-prolyl]amino}-1-thio-L-threo-alpha-D-galacto-octopyranoside hydrochloride (1:1)
• L-threo-α-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-, monohydrochloride, (2S-trans)-
• Clindamycin hydrochloride
• L-threo-α-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-, hydrochloride (1:1)
• L-threo-α-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-, monohydrochloride
• L-threo-α-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-, monohydrochloride, trans- α-

Clindamycin Hydrochloride Monohydrate

CAS: 18323-44-9 21462-39-558207-19-5

• Fórmula: C₁₈H₃₃ClN₂O₅S·HCl·H₂O
• Pureza: >98.0%(T)(HPLC)
• Cor e Forma: White to Almost white powder to crystal
• Peso molecular: 479.46

Clindamycin hydrochloride RS

CAS: 21462-39-5

Clindamycin hydrochloride CRS

CAS: 21462-39-5

• Fórmula: C₁₈H₃₄Cl₂N₂O₅S
• Cor e Forma: Crystalline Powder. White. Powder.
• Peso molecular: 461.444

Clindamycin Hydrochloride

CAS: 21462-39-5

• Fórmula: C₁₈H₃₄Cl₂N₂O₅S
• Pureza: 95%
• Cor e Forma: Solid
• Peso molecular: 461.444

Clindamycin hydrochloride

CAS: 21462-39-5

• Fórmula: C₁₈H₃₃ClN₂O₅S·ClH
• Pureza: 94% (q-nmr) (calculated (Typical Value in Batch COA)
• Cor e Forma: white powder
• Peso molecular: 461.44g/mol

Clindamycin HCl (Clindamycin Phosphate EP Impurity E HCl)

CAS: 21462-39-5

• Fórmula: C₁₈H₃₃ClN₂O₅S·HCl
• Cor e Forma: White To Off-White Solid
• Peso molecular: 424.99 36.46

Clindamycin hydrochloride

CAS: 21462-39-5

• Fórmula: C₁₈H₃₃ClN₂O₅S·HCl·xH₂O
• Pureza: ≥ 800μg/mg (C18H33ClN2O5S, as is)
• Cor e Forma: White to off-white powder
• Peso molecular: 461.44 (anhydrous)

Clindamycin hydrochloride, 97%

CAS: 21462-39-5

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Fórmula: C₁₈H₃₄Cl₂N₂O₅S
• Pureza: 97%
• Cor e Forma: Crystalline powder, White to almost white
• Peso molecular: 461.44

Clindamycin Hydrochloride

CAS: 21462-39-5

• Fórmula: C₁₈H₃₃ClN₂O₅S·ClH
• Cor e Forma: Neat
• Peso molecular: 461.44

Clindamycin 1000 µg/mL in Acetonitrile

CAS: 21462-39-5

• Fórmula: C₁₈H₃₃ClN₂O₅S·ClH
• Cor e Forma: Single Solution
• Peso molecular: 461.44

Clindamycin hydrochloride

CAS: 21462-39-5

• Fórmula: C₁₈H₃₃ClN₂O₅S·ClH
• Cor e Forma: Neat
• Peso molecular: 461.44

Clindamycin hydrochloride

CAS: 21462-39-5

Clindamycin hydrochloride (Clinimycin HCl) inhibits protein synthesis by acting on the 50S ribosomal. Clindamycin is …

• Fórmula: C₁₈H₃₃ClN₂O₅S·HCl
• Pureza: 99.80%
• Cor e Forma: White Crystalline Powder
• Peso molecular: 461.44

Clindamycin Hydrochloride

CAS: 21462-39-5

Impurity Clindamycin Phosphate EP Impurity E Stability Hygroscopic Applications Clindamycin Hydrochloride (Clindamycin Phosphate EP Impurity …

• Fórmula: C₁₈H₃₃ClN₂O₅S·ClH
• Cor e Forma: White To Off-White
• Peso molecular: 461.44

Clindamycin hydrochloride

CAS: 21462-39-5

Inhibitor of protein synthesis; lincosamide class

• Fórmula: C₁₈H₃₄Cl₂N₂O₅S
• Cor e Forma: White Powder
• Peso molecular: 461.44 g/mol

Clindamycin hydrochloride - 94%

CAS: 21462-39-5

Purity min. 94%; Inhibitor of protein synthesis; lincosamide class

• Fórmula: C₁₈H₃₃ClN₂O₅S·HCl
• Cor e Forma: Powder
• Peso molecular: 461.44 g/mol

Cis-Clindamycin Hydrochloride

CAS: 21462-39-5

• Fórmula: C₁₈H₃₃ClN₂O₅S·ClH
• Cor e Forma: Neat
• Peso molecular: 460.15655