CAS 2190490-31-2
:Fórmula:C19H16ClFN4O3
InChI:InChI=1S/C19H16ClFN4O3/c1-28-16-8-14-11(7-15(16)25-17(26)4-5-18(25)27)19(23-9-22-14)24-10-2-3-13(21)12(20)6-10/h2-3,6-9,17,26H,4-5H2,1H3,(H,22,23,24)
Chave InChI:YYROAISCXBYHNT-UHFFFAOYSA-N
SMILES:COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)N4C(CCC4=O)O
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Pureza (%)
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100
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0
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50
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90
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95
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100
Foram encontrados 7 produtos.
1-(4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)-5-hydroxypyrrolidin-2-one (Dacomitinib Impurity)
CAS:1-(4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)-5-hydroxypyrrolidin-2-one (Dacomitinib Impurity)Fórmula:C19H16ClFN4O3Pureza:98%Peso molecular:402.811-(4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)-5-hydroxypyrrolidin-2-one (Dacomitinib Impurity)
CAS:Fórmula:C19H16ClFN4O3Pureza:98%Peso molecular:402.8067Dacomitinib impurity 3
CAS:Dacomitinib impurity 3 is a contaminant found in Dacomitinib.Fórmula:C19H16ClFN4O3Peso molecular:402.811-(4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)-5-hydroxypyrrolidin-2-one (Dacomitinib Impurity)
CAS:Pureza:98%Peso molecular:402.81Des-(4-(1-piperidinyl)-2-Butenamide) Dacomitinib-5-hydroxypyrrolidin-2-one
CAS:Produto ControladoApplications Des-(4-(1-piperidinyl)-2-Butenamide) Dacomitinib-5-hydroxypyrrolidin-2-one is a derivative of Dacomitinib (D101575), which is an Erb-inhibitor, or an inhibitor of the members of the epidermal growth factor receptor family. Used as an ant-cancer agent due to observation of over-expressed epidermal growth factor receptor in nearly all cases of squamous cell carcinoma in the head and neck.
References Williams, J. et al.: PLoS., 9, e98557 (2014); Peters, S. et al.: Canc. Treatment Rev., 40, 917 (2014);Fórmula:C19H16ClFN4O3Cor e Forma:NeatPeso molecular:402.807
